血朗Ｒ膜衣錠２５０公絲（匹洛布克）

国家: 台湾

语言: 中文

来源: 衛生福利部食品藥物管理署 (Ministry of Health and Welfare, Food And Drug Administration)

有效成分:

PROBUCOL

可用日期:

永信藥品工業股份有限公司 台中市大甲區頂店里中山路一段1191號 (56065601)

ATC代码:

C10AX02

药物剂型:

膜衣錠

组成:

PROBUCOL (2406001000) 250MG

每包单位数:

玻璃瓶裝

类:

製　劑

处方类型:

須由醫師處方使用

厂商:

永信藥品工業股份有限公司台中幼獅廠 台中市大甲區日南里工九路２７號 TW

治疗领域:

probucol

疗效迹象:

高膽固醇血症

產品總結:

有效日期: 2028/08/05; 英文品名: HELLON FILM COATED TABLETS 250MG (PROBUCOL)

授权日期:

1986-08-05

资料单张

®
Probucol
Probucol
.........................................................
250 mg
Potato Starch
Microcrystalline Cellulose
Sodium Starch Glycolate
Magnesium Stearate
Polyethylene Glycol 6000
Hydroxypropyl
Methyl Cellulose
Dimethylpolysiloxane
Probucol
Probucol
Low-Density
Lipoprotein (LDL)
LDL-
High-Density Lipoprotein (HDL)
High-Density
HDL
LDL
LDL-
HDL-
Very
Low-Density
Lipoprotein
(VLDL)
Probucol
LDL
Probucol
Desmostreol
7-Dehydrocholesterol
Probucol
Probucol
Probucol
500mg/
Probucol
116
23.6±17.2 mcg/mL (±S.D.)
78.3 mcg/mL
Probucol
40
21.5±16.5
mcg/mL
(±S.D.)
62.0
mcg/mL
12
19.0 mcg/mL
6
60%
6
80%
1984
12
"
"-NIHCDCP
LDL-
Probucol
HDL-
Probucol
Probucol
Probucol
(Type IIa
Type IIb
)
LDL-
Probucol
LDL-
(Type IIb)
LDL
VLDL
Probucol
LDL-
HDL-
LDL
LDL-
HET-002
029077
HELLON
(Probucol)
LDL-
[(0.16×
)HDL
]
400mg/dL
LDL-
HDL-
Probucol
HDL-
1000 mg
500 mg 1
250 mg
2
PROBUCOL
LDL-
HDL-
PROBUCOL
PROBUCOL
LDL-
HDL-
LDL-
-
B
50
PROBUCOL
6
PROBUCOL
PROBUCOL
PROBUCOL
QT
PROBUCOL
QT
QT
PROBUCOL
PROBUCOL
1.
PROBUCOL
2.
ECG
QT
QT
15%
40
50
60
70
80
86
92
100
109
120
133
VALUES CALCULATED FROM BURCH GE. WINSOR T.A PRIMER
OF ELECTROCARDIOGRAPHY.
PHILADELPHIA, PA: LEA AND FEBIGER; 1958; P.272(TABLE 6)
3.
PROBUCOL
ECG
Film Coated Tablets
250mg
250
PROBUCOL
ISOPROTERENOL
PROBUCOL
10
60
60
EPINEPHRINE
PROBUCOL
LRC-CPPT
SEQUESTRANT (CHOLESTRAMINE)
LDL-
7
CHD
7%
CHOLESTRAMINE
8.6%
CHD
24%
INNONFATAL
19% (P
0.05
SINGLE TRIAL TEST)
35
59
265 MG/DL
SEQUESTRANT
CHOLESTRAMINE
PROBUCOL
CHOLESTRAMINE
PROBUCOL
HDL
PROBUCOL
4
1000
4.
QT
A.
B.
QT
PHENOTHIAZIDE
C.
D.
Β-
AV-
(DIGOXINE)
E.
5.
PROBUCOL
PROBUCOL
A.
B.
C.
Β-
AV-
(DIGOXINE)
D.
ECG QT
TOSADES DE POINTS
PROBUCOL
15
3
5
PROBUCOL
PROBUCOL
PROBUCOL
PROBUCOL
LD
50
5 G/KG
PROBUCOL
8
4
QT
QT
30
50%
QT
PROBUCOL
20 MCG/ML
QT
75MSEC
QT
40 MCG/ML
PROBUCOL
20 MCG/ML
40 MCG/ML
PROBUCOL
3
30
1/3
8
2
10
5
PROBUCOL
20
50
MCG/ML
ECG
QT
PROBUCOL
CHOLESTYRAMINE
HDL-
LDL-
2
32
PROBUCOL
12
PROBUCOL
EPINEPHRINE
PROBUCOL
PROBUCOL
PROBUCOL
PROBUCOL
LD
50
5 G/KG
2
PROBUCOL
90%
®
2145308
2145308
0.