Quốc gia: Malaysia
Ngôn ngữ: Tiếng Anh
Nguồn: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)
Paracetamol; CAFFEINE
UNAM PHARMACEUTICAL (M) SDN BHD
Paracetamol; CAFFEINE
20 Tablets
PT MEDIFARMA LABORATORIES, INC
1 _Consumer Medication Information Leaflet (RiMUP) _ WATSONS PAIN & FEVER RELIEF EXTRA TABLET (Paracetamol 500mg, Caffeine 65mg) WHAT IS IN THIS LEAFLET 1. What Watsons Pain & Fever Relief EXTRA Tablet is used for 2. How Watsons Pain & Fever Relief EXTRA Tablet works 3. Before you use Watsons Pain & Fever Relief EXTRA Tablet 4. How to use Watsons Pain & Fever Relief EXTRA Tablet 5. While you are using it 6. Side effects 7. Storage and Disposal of Watsons Pain & Fever Relief EXTRA Tablet 8. Product Description 9. Manufacturer and Product Registration Holder 10. Date of revision 1. WHAT WATSONS PAIN & FEVER RELIEF EXTRA TABLET IS USED FOR Watsons Pain & Fever Relief EXTRA Tablet is used for the treatment of most painful and febrile conditions, for example: - Headache, including migraine - Toothache - Rheumatic pain - Menstrual pain - Relief of the symptoms of colds, influenza and sore throat 2. HOW WATSONS PAIN & FEVER RELIEF EXTRA TABLET WORKS The tablet contains 500mg Paracetamol, 65mg Caffeine. Paracetamol works by relieving pain. The mechanism of analgesic action has not been fully determined. Paracetamol may act predominantly by inhibiting prostaglandin synthesis in the central nervous system (CNS) (specifically cyclooxygenase (COX)-2) and, to a lesser extent, through a peripheral action by blocking pain-impulse generation. Caffeine is a CNS stimulant. It stimulates all levels of the CNS, although its cortical effects are milder and of shorter duration than those of amphetamines. Contact your doctor if you have any questions about the purpose of the Watsons Pain & Fever Relief EXTRA Tablet provided to you. Your doctor may prescribe Watsons Pain & Fever Relief EXTRA Tablet for other purposes. 3. BEFORE YOU USE WATSONS PAIN & FEVER RELIEF EXTRA TABLET - _When you must not to use it _ Do not consume this medicine if you have allergies towards: - Paracetamol and any other ingredients listed at the end of this leaflet - Any other medicine which are similar Do not consume Watsons Pain & Fever Relief EXTRA Tablet if Đọc toàn bộ tài liệu
KNIFEGUIDE INSERT Dimension : 98 x 140 mm 140 mm 98 mm _FRONT SIDE_ _BACK SIDE_ Watsons OTC_Pain & Fever Relief EXTRA Tablet insert (MY version) 23-02-2022(R9) Black WATSONS PAIN & FEVER RELIEF EXTRA TABLET NAME AND STRENGTH OF ACTIVE SUBSTANCE(S) Paracetamol 500mg Caffeine 65mg PRODUCT DESCRIPTION Watsons Pain and Fever Relief EXTRA Tablet is a white, modified capsule-shaped, 0.662” x 0.300” in diameter, convex, bisected line on one side and plain on the other side. PHARMACODYNAMICS Paracetamol Paracetamol is a centrally acting analgesic and antipyretic with minimal anti-inflammatory properties Analgesic The mechanism of analgesic action has not been fully determined. Paracetamol may act predominantly by inhibiting prostaglandin synthesis in the central nervous system (CNS) (specifically cyclooxygenase (COX)-2) and, to a lesser extent, through a peripheral action by blocking pain-impulse generation. The peripheral action may also be due to inhibition of prostaglandin synthesis or inhibition of the synthesis or actions of other substances that sensitize pain receptors to mechanical or chemical stimulation. Antipyretic Paracetamol acts centrally on the hypothalamic heat-regulating centre to produce peripheral vasodilatation resulting in increased blood flow through the skin, sweating and heat loss. Paracetamol reduces fever by inhibiting the formulation and release of prostaglandins in the CNS and by inhibiting endogenous pyrogens at the hypothalamic thermoregulatory centre. Caffeine Caffeine is a CNS stimulant. It stimulates all levels of the CNS, although its cortical effects are milder and of shorter duration than those of amphetamines. Analgesia adjunct Caffeine constricts cerebral vasculature with an accompanying decrease in the cerebral blood flow and in the oxygen tension of the brain. It is believed that caffeine helps to relieve headache by providing more rapid onset of action and/or enhancing pain relief with lower doses of analgesic. The combination of paracetamol and caffeine is a well-established Đọc toàn bộ tài liệu