Quốc gia: Vương quốc Anh
Ngôn ngữ: Tiếng Anh
Nguồn: MHRA (Medicines & Healthcare Products Regulatory Agency)
Phenylephrine hydrochloride
Martindale Pharmaceuticals Ltd
Phenylephrine hydrochloride
100microgram/1ml
Solution for injection
Intravenous
No Controlled Drug Status
Valid as a prescribable product
BNF: ; GTIN: 5026468761425
WHAT IS IN THIS LEAFLET 1. What Phenylephrine is and what it is used for 2. What you need to know before you use Phenylephrine 3. How to use Phenylephrine 4. Possible side effects 5. How to store Phenylephrine 6. Contents of the pack and other information 1. WHAT PHENYLEPHRINE IS AND WHAT IT IS USED FOR This drug belongs to a group called adrenergic or dopaminergic agents. Phenylephrine is used to treat low blood pressure that can occur during different types of anesthesia. 2. WHAT YOU NEED TO KNOW BEFORE YOU USE PHENYLEPHRINE DO NOT USE PHENYLEPHRINE IF: • you are allergic (hypersensitive) to phenylephrine or any of the other ingredients of this medicine (listed in section 6). • you suffer from hypertension (increased blood pressure) • you are suffering from a peripheral vascular disease (poor blood circulation) • you take a non•selective monoamine oxidase inhibitor (MAO) (or within 2 weeks of their withdrawal) for treatment of depression (iproniazide, nialamide). • you suffer from a severe overactive thyroid gland (hyperthyroidism) WARNINGS AND PRECAUTIONS Talk to your doctor, pharmacist or nurse before using Phenylephrine : • if you are elderly • if you have an overactive thyroid gland • if you suffer from heart problems as a slow pulse, heart block (partial), heart muscle disease, poor blood circulation in the heart, severe peripher vascular insufficiency, heart rhythm disorders, tachycardia (high heart rate), bradycardia (low heart rate), angina pectoris • if you have poor blood circulation in the brain • if you have atherosclerosis (hardening and thickening of the blood vessel walls) • if you have diabetes mellitus • if you are treated with oxytocin as the effect on the blood vessels can be enhanced and cause very high blood pressure and stroke in the period immediately after childbirth • if you suffer from arterial hypertension • if you suffer from a closed angle glaucoma In patients with serious heart failure phenylephrine may worsen the heart failure as a consequence of bloo Đọc toàn bộ tài liệu
OBJECT 1 PHENYLEPHRINE 0.1 MG/ML, SOLUTION FOR INJECTION Summary of Product Characteristics Updated 06-Apr-2016 | Martindale Pharma 1. Name of the medicinal product Phenylephrine 0.1 mg/ml, solution for injection 2. Qualitative and quantitative composition One ml of Phenylephrine 0.1 mg/ml, solution for injection, contains phenylephrine hydrochloride equivalent to 0.1 mg of phenylephrine. - Each 5 ml ampoule of Phenylephrine 0.1 mg/ml contains phenylephrine hydrochloride equivalent to 0.5 mg phenylephrine. - Each 10 ml ampoule of Phenylephrine 0.1 mg/ml contains phenylephrine hydrochloride equivalent to 1.0 mg phenylephrine. Excipient with known effect: Each 10 ml ampoule contains 1,6 mmol (36,8 mg) sodium. Each 5 ml ampoule contains 0,8 mmol (18,4 mg) sodium. For the full list of excipients, see section 6.1. 3. Pharmaceutical form Solution for injection. Clear, colourless solution with an osmolality of 270-300 mOsm/kg. pH: 4,5-6,5. 4. Clinical particulars 4.1 Therapeutic indications Treatment of hypotension during spinal, epidural and general anaesthesia. 4.2 Posology and method of administration Posology _Adults_ _Intravenous bolus injection:_ Normal dose is 50 to 100 micrograms, which can be repeated until the desired effect is attained. One bolus dose should not exceed 100 micrograms. _Continuous infusion:_ Initial dose is 25 to 50 micrograms/min. The doses may be increased or decreased to maintain the systolic blood pressure close to the normal value. Doses between 25 and 100 micrograms/min have been assessed to be effective. _Renal impairment:_ Lower doses of phenylephrine may be needed in patients with impaired renal function. _Hepatic impairment:_ Higher doses of phenylephrine may be needed in patients with cirrhosis of the liver. _Older people:_ Treatment of the elderly should be carried out with care. _Paediatric population:_ The safety and efficacy of phenylephrine in children have not been established. No data are available. Method of administration : Parenteral administration. Intravenous bolus injec Đọc toàn bộ tài liệu