NISOLON TABLET 5MG

Quốc gia: Malaysia

Ngôn ngữ: Tiếng Anh

Nguồn: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)

Thành phần hoạt chất:

PREDNISOLONE

Sẵn có từ:

DUOPHARMA (M) SDN. BHD.

INN (Tên quốc tế):

PREDNISOLONE

Các đơn vị trong gói:

1000 Tablet Tablets

Sản xuất bởi:

DUOPHARMA (M) SDN. BHD.

Tờ rơi thông tin

1
NISOLON TABLET
Prednisolone (5mg)
_CONSUMER MEDICATION INFORMATION LEAFLET (PIL_)
WHAT IS IN THE LEAFLET
1.
What NISOLON TABLET is
used for
2.
How
NISOLON
TABLET
works
3.
Before you use NISOLON
TABLET
4.
How
to
use
NISOLON
TABLET
5.
While you are using NISOLON
TABLET
6.
Side effects
7.
Storage
and
Disposal
of
NISOLON TABLET
8.
Product description
9.
Manufacturer
and
Product
Registration Holder
10.
Date of Revision
WHAT NISOLON TABLET IS
USED FOR
NISOLON TABLET is used in the
treatment
of
many
different
conditions.
Some
of
these
conditions
include:
severe
allergies, severe or chronic asthma,
skin
problems,
arthritis,
inflammatory
diseases
of
the
bowel, cancer and “auto-immune”
diseases.
It is also used to prevent or reduce
the
symptoms
of
inflammation
(such as swelling, redness, pain,
tenderness or itching) in any part of
the body.
These
symptoms
can
occur
in
response to injury or can be caused
by many different conditions.
Ask your doctor if you have any
questions
about
why
NISOLON
TABLET has been prescribed for
you.
Your
doctor
may
have
prescribed it for another purpose.
HOW NISOLON TABLET WORKS
NISOLON
TABLET
contains
prednisolone as the active
ingredient.
Prednisolone
belongs
to
a
group
of
medicines
called
corticosteroids
which
are
a
synthetic
version
of
a
naturally
occurring
body
hormone
called
cortisol.
NISOLON
TABLET
works
by
entering
inflammatory
cells
and
blocking
the
inflammatory
reaction.
This
medicine
is
only
able
to
prevent
or
reduce
symptoms
of
your
condition,
it
does not cure it.
BEFORE
YOU
USE
NISOLON
TABLET
-
_When you must not use it_
_ _
Do not use NISOLON TABLET if
you are allergic to prednisolone or
any of the other ingredients listed
at the end of the leaflet.
Symptoms of an allergic reaction
may include shortness of breath,
wheezing
or
difficulty
in
breathing;
swelling
of
the
face,
lips, tongue or any other parts of
the body; rash, itching or hives on
the skin.
Do not take it if you have
•
Osteoporosis (softening of the
bone)
•
Stomach ulcer
•
Fungal infection
•
Mental disorder

Đặc tính sản phẩm

[DUOPHARMA (M) SDN BHD]
Page 1 of 3
[REVISION DATE:25.08.2022]
NISOLON TABLET 5 MG
DESCRIPTION:
A white, round shape tablet, 7 mm in diameter with marking 'd' and
scored on another side.
COMPOSITION:
Each tablet contains Prednisolone 5 mg.
PHARMACODYNAMICS:
Prednisolone is a synthetic corticosteroid with glucocorticoid and
anti-inflammatory effects. Prednisolone exceeds hydrocortisone in
glucocorticoid and anti-
inflammatory activity, being about three times more potent on a weight
basis than the parent hormone, but is considerably less active than
hydrocortisone in
mineralocorticoid activity.
Prednisolone like hydrocortisone is a potent therapeutic agent
influencing the biochemical behaviour of most tissues of the body.
The mechanism of action of corticosteroids is thought to be by control
of protein synthesis. Corticosteroids react with receptor proteins in
the cytoplasm of
sensitive cells in many tissues to form a steroid- receptor complex.
Corticosteroids are palliative symptomatic treatment by virtue of
their anti-inflammatory effects; they are never curative.
PHARMACOKINETICS:
Prednisolone is readily absorbed from the gastrointestinal tract.
ABSORPTION: The plasma half-life after oral administration of
prednisolone ranges from 3 to 4 hours. Oral bioavailability varies
widely between subjects. Peak
plasma concentrations of prednisolone are obtained 1 or 2 hours after
oral administration and prednisolone has a usual plasma half-life of 2
to 4 hours. Its initial
absorption, but not its overall bioavailability, is affected by food.
DISTRIBUTION: Prednisolone is 90 to 95% bound to plasma proteins.
METABOLISM: Prednisolone is conjugated in the liver and to some extent
in the kidney.
EXCRETION: Prednisolone is excreted in the urine as free and
conjugated metabolites, together with an appreciable proportion of
unchanged prednisolone.
Prednisolone crosses the placenta and small amounts are excreted in
breast milk.
INDICATION:
COLLAGEN DISEASES: (eg. rheumatoid arthritis, acute rheumatic fever,
SLE).
ALLERGIC DISEASE