LIDOCAINE HYDROCHLORIDE- lidocaine gel

Quốc gia: Hoa Kỳ

Ngôn ngữ: Tiếng Anh

Nguồn: NLM (National Library of Medicine)

Thành phần hoạt chất:

LIDOCAINE (UNII: 98PI200987) (LIDOCAINE - UNII:98PI200987)

Sẵn có từ:

Aidarex Pharmaceuticals LLC

Tuyến hành chính:

TOPICAL

Loại thuốc theo toa:

PRESCRIPTION DRUG

Chỉ dẫn điều trị:

Lidocaine Hydrochloride USP is contraindicated in patients with a known history of hypersensitivity to local anesthetics of the amide type or to other components of LidoRx 3%. Do not use LidoRx 3% on traumatized mucosa or in the presence of secondary bacterial infection of the area of proposed application.

Tóm tắt sản phẩm:

Lido Rx 3%(Lidocaine HCl USP 3%)    1.01 oz (28.5g) 30mL Airless Pump - NDC 53217-0064-01 Gensco Labratories, LLC 12741 Miramar Parkway Miramar, FL 33027 Repackaged By : Aidarex Pharmaceuticals LLC, Corona, CA 92880

Tình trạng ủy quyền:

unapproved drug other

Đặc tính sản phẩm

LIDOCAINE HYDROCHLORIDE- LIDOCAINE GEL
AIDAREX PHARMACEUTICALS LLC
_Disclaimer: This drug has not been found by FDA to be safe and
effective, and this labeling has not been_
_approved by FDA. For further information about unapproved drugs,
click here._
----------
LIDORX (LIDOCAINE HCL USP) 3%
RX ONLY
DO NOT USE IN THE EYES.
DESCRIPTION
Lidocaine HCL USP, 3% contains a local anesthetic agent and is
administered topically. See
INDICATIONS AND USAGE for specific uses.
Lidocaine HCL USP, 3% contains lidocaine, which is chemically
designated as acetamide, 2-
(diethylamino)-_N_-(2,6-dimethylphenyl)-, and has the following
structural formula:
Composition of Lidocaine HCL USP, 3%: Each gram contains lidocaine
hydrocloride USP, 3% in a
water soluble base containing AQUA (DEIONIZED WATER), CARBOMER,
ISOPROPYL
ALCOHOL, PETROLATUM, POLYSORBATE-20, TRIETHANOLAMINE.
CLINICAL PHARMACOLOGY
MECHANISM OF ACTION
LidoRx 3% releases Lidocaine Hydrochloride USP from a mild acidic
vehicle to stabilize the neuronal
membrane by inhibiting the ionic fluxes required for initiation and
conduction of impulses, thereby
effecting local anesthetic action. A mild acidic vehicle lowers pH to
increase protection against
alkaline irritations and to provide a favorable environment for
healing.
ONSET OF ANESTHESIA
LidoRx 3% effects local, topical anesthesia. The onset of action is
3-5 minutes.
HEMODYNAMICS
Excessive blood levels may cause changes in cardiac output, total
peripheral resistance, and mean
arterial pressure. These changes may be attributable to a direct
depressant effect of the local anesthetic
agent on various components of the cardiovascular system.
PHARMACOKINETICS AND METABOLISM
Lidocaine Hydrochloride USP may be absorbed following topical
administration to mucous membranes
or open wounds, its rate and extent of absorption depending upon the
specific site of application,
duration of exposure, concentration, and total dosage. In general, the
rate of absorption of local
anesthetic agents following topical application occurs most rapidl