Quốc gia: Úc
Ngôn ngữ: Tiếng Anh
Nguồn: Department of Health (Therapeutic Goods Administration)
esomeprazole magnesium
Sandoz Pty Ltd
Esomeprazole magnesium
Registered
ESOMEPRAZOLE SZ 1 ESOMEPRAZOLE SZ _esomeprazole (as magnesium) enteric-coated tablet _ CONSUMER MEDICINE INFORMATION WHAT IS IN THIS LEAFLET This leaflet answers some of the common questions people ask about Esomeprazole SZ enteric-coated tablet. It does not contain all the information that is known about Esomeprazole SZ enteric-coated tablet. It does not take the place of talking to your doctor or pharmacist. All medicines have risks and benefits. Your doctor will have weighed the risks of you taking Esomeprazole SZ enteric-coated tablet against the benefits they expect it will have for you. IF YOU HAVE ANY CONCERNS ABOUT TAKING THIS MEDICINE, ASK YOUR DOCTOR OR PHARMACIST. KEEP THIS LEAFLET WITH THE MEDICINE. You may need to read it again. WHAT ESOMEPRAZOLE SZ ENTERIC-COATED TABLET IS USED FOR _REFLUX OESOPHAGITIS _ Esomeprazole SZ enteric-coated tablet is taken to treat reflux oesophagitis. This can be caused by "washing back" (reflux) of food and acid from the stomach into the food pipe (oesophagus). Reflux can cause a burning sensation in the chest rising up to the throat, also known as heartburn. Esomeprazole SZ enteric-coated tablet is also taken to help stop reflux oesophagitis coming back or relapsing. _UPPER GASTROINTESTINAL _ _SYMPTOMS ASSOCIATED WITH _ _NON-STEROIDAL ANTI-_ _INFLAMMATORY DRUGS _ _(NSAIDS) THERAPY _ Esomeprazole SZ enteric-coated tablet is taken to treat the symptoms of pain or discomfort, in the stomach caused by NSAIDs, a type of medicine for pain or inflammation. Esomeprazole SZ enteric-coated tablet is also taken to help heal and prevent ulcers caused by NSAIDs. _PEPTIC ULCERS ASSOCIATED _ _WITH HELICOBACTER PYLORI _ _INFECTION _ Most people who have a peptic (gastric and duodenal) ulcer also have a bacterium called Helicobacter pylori in their stomach. Depending on the position of the ulcer it is called a gastric or duodenal ulcer. A gastric ulcer occurs in the stomach. A duodenal ulcer occurs in the duodenum which is the tube leading out from the stomach. If you have a peptic ulc Đọc toàn bộ tài liệu
_Product Information Page 1 _ _Esomeprazole SZ 20 mg and 40 mg enteric coated tablets _ _10/2017 _ Sandoz Pty Ltd Version 01 PRODUCT INFORMATION ESOMEPRAZOLE SZ 20 MG AND 40 MG ENTERIC COATED TABLETS NAME OF MEDICINE Esomeprazole magnesium Esomeprazole SZ (esomeprazole enteric-coated tablet) is a proton pump inhibitor. The active ingredient in Esomeprazole SZ (esomeprazole enteric-coated tablet) is esomeprazole magnesium amorphous, a substituted benzimidazole. Esomeprazole is the S-isomer of omeprazole. It is optically stable _in vivo_, with negligible conversion to the R-isomer. The chemical name is di-(S)-5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1_H_- benzimidazole, magnesium salt. The chemical structure of esomeprazole magnesium amorphous is: CAS number: [161973-10-0] Molecular formula: C 34 H 36 N 6 O 6 S 2 Mg Molecular weight: 713.12 (amorphous) DESCRIPTION Esomeprazole SZ (esomeprazole enteric-coated 20 mg and 40 mg tablets) is comprised of enteric-coated pellets containing esomeprazole (as magnesium amorphous). The tablets contain the following inactive ingredients: Non Pareil seeds 40-50 (which contain maize starch and sucrose), hypolose, crospovidone, sucrose, light magnesium oxide, purified talc, macrogol 6000, Methacrylic acid- ethyl acrylate copolymer (1:1), glyceryl monostearate, macrogol 400, polysorbate 80, hypromellose phthalate, microcrystalline cellulose, povidone, pregelatinised maize starch, silicon dioxide, hypromellose and lactose monohydrate. The 20 mg and 40 mg tablets are coloured with titanium dioxide, iron oxide red, and 20mg tablet also contain iron oxide yellow. PHARMACOLOGY Esomeprazole magnesium amorphous reversibly reduces gastric acid secretion by specifically inhibiting the gastric enzyme H+, K+-ATPase proton pump in the parietal cell. Both the R- and S-isomer of omeprazole have similar pharmacodynamic activity. In humans, acid control with esomeprazole is dose dependent and is significantly greater, more sustained and less variable compared to that obta Đọc toàn bộ tài liệu