Quốc gia: Hoa Kỳ
Ngôn ngữ: Tiếng Anh
Nguồn: NLM (National Library of Medicine)
oxytetracycline hydrochloride (UNII: 4U7K4N52ZM) (oxytetracycline anhydrous - UNII:SLF0D9077S)
Durvet, Inc.
oxytetracycline hydrochloride
oxytetracycline anhydrous 100 mg in 1 mL
INTRAVENOUS
OTC
A great many of the pathogens involved in cattle diseases are known to be susceptible to oxytetracycline hydrochloride therapy. Many strains of organisms, however, have shown resistance to oxytetracycline. In the case of certain coliforms, streptococci and staphylococci, it may be advisable to conduct culture and sensitivity testing to determine susceptibility of the infecting organism to oxytetracycline. In this manner, the likelihood of successful treatment with Duramycin-100 solution can be determined in advance.
Abbreviated New Animal Drug Application
DURAMYCIN 100- OXYTETRACYCLINE HYDROCHLORIDE INJECTION, SOLUTION DURVET, INC. ---------- DURAMYCIN-100 OXYTETRACYCLINE HYDROCHLORIDE INJECTION ANADA 200-452, APPROVED BY FDA ANTIBIOTIC Each mL contains: 100 MG OXYTETRACYCLINE HCL For use in Beef Cattle, Beef Calves, Non-lactating Dairy Cattle and Dairy Calves Only DESCRIPTION Duramycin-100 [oxytetracycline hydrochloride] is a sterile ready-to-use preparation containing 100 mg/mL oxytetracycline HCl, for administration of the broad spectrum antibiotic, oxytetracycline, by injection. ANTIBIOTIC ACTION OF OXYTETRACYCLINE Oxytetracycline is effective against a wide range of gram-negative and gram-positive organisms that are pathogenic for cattle. The antibiotic is primarily bacteriostatic in effect, and is believed to exert its antimicrobial action by the inhibition of microbial protein synthesis. The antibiotic activity of oxytetracycline is not appreciably diminished in the presence of body fluids, serum or exudates. Since the drugs in the tetracycline class have similar antimicrobial spectra, organisms can develop cross resistance among them. Oxytetracycline is concentrated by the liver in the bile and excreted in the urine and feces at high concentrations and in a biologically active form. WARNING Discontinue treatment with Duramycin-100 at least 22 days prior to slaughter of the animal. Not for use in lactating dairy animals. A withdrawal period has not been established for this product in pre-ruminating calves. Do not use in calves to be processed for veal. CAUTION Rapid intravenous administration may result in animal collapse. Oxytetracycline should be administered intravenously slowly over a period of at least 5 minutes. If no improvement occurs within 24 to 48 hours, consult a veterinarian. Do not use the drug for more than 4 consecutive days. Use beyond 4 days or doses higher than maximum recommended dose may result in antibiotic tissue residues beyond the withdrawal period. PRECAUTIONS The improper or accidental injection of the drug outside of the vein wi Đọc toàn bộ tài liệu