Quốc gia: Vương quốc Anh
Ngôn ngữ: Tiếng Anh
Nguồn: MHRA (Medicines & Healthcare Products Regulatory Agency)
Captopril
Tillomed Laboratories Ltd
C09AA01
Captopril
12.5mg
Oral tablet
Oral
No Controlled Drug Status
Valid as a prescribable product
BNF: 02050501; GTIN: 5024655000340 5024655000357
WHAT THIS MEDICINE IS AND WHAT IT IS USED FOR 1 Captopril belongs to a group of medicines called Angiotensin Converting Enzyme (ACE) Inhibitors. These work by helping to widen your blood vessels, which then make it easier for your heart to pump blood through them. Captopril is used to treat the following: Mild to moderately high blood pressure (hypertension) Severely high blood pressure (hypertension) where standard treatment is ineffective or unsuitable Treatment or prevention of heart failure Short-term (4 weeks) treatment within the first 24 hours of a heart attack Kidney problems caused by diabetes WHAT YOU NEED TO KNOW BEFORE YOU TAKE CAPTOPRIL 2 DO NOT TAKE CAPTOPRIL IF: You are allergic to Captopril, ACE Inhibitors or any of the other ingredients of this medicine (listed in Section 6) You are more than 3 months pregnant (it is also better to avoid Captopril in early pregnancy - see "Pregnancy and breast-feeding" section) You have a history of suffering from swelling of the deeper layers of the skin caused by a build-up of fluid relating to previous treatment with an ACE Inhibitor (angioedema) You suffer from an inherited swelling of the deeper layers of the skin caused by a build-up of fluid or without an identifiable cause (hereditary or idiopathic angioedema) If you are breast-feeding (see "Pregnancy and breast-feeding" section) If you have diabetes or impaired kidney function and you are treated with a blood pressure lowering medicine containing aliskiren WARNINGS AND PRECAUTIONS If you are taking any of the following medicines used to treat high blood pressure: An angiotensin II receptor blocker (ARBs) (also known as sartans - for example valsartan, telmisartan, irbesartan), in particular if you have diabetes-related kidney problems Aliskiren Your doctor may check your kidney function, blood pressure, and the amount of electrolytes (e.g. potassium) in your blood at regular intervals. See also information under the heading "Do not take Captopril" TALK TO YOUR DOCTO Đọc toàn bộ tài liệu
SUMMARY OF PRODUCT CHARACTERISTICS 1 NAME OF THE MEDICINAL PRODUCT Captopril 12.5mg Tablets 2 QUALITATIVE AND QUANTITATIVE COMPOSITION Each tablet contains 12.5 mg captopril Excipients with known effect : Each tablet contains 25 mg lactose (as lactose monohydrate) For the full list of excipients, see section 6.1 3 PHARMACEUTICAL FORM Tablet Round, white tablets of diameter 6.0 -6.2mm with a break mark on one side, convex on the other side. The score line is only to facilitate breaking for the ease of swallowing and not to divide into equal doses 4 CLINICAL PARTICULARS 4.1 THERAPEUTIC INDICATIONS Hypertension: The management of mild to moderate hypertension. In severe hypertension it should be used where standard therapy is ineffective or inappropriate. Congestive heart failure: Captopril is indicated for the treatment of congestive heart failure. The drug should be used together with diuretics, and when appropriate, digitalis and beta-blockers. In patients on doses of over 100 mg daily plus or minus a diuretic, in those with severe renal impairment or those with severe congestive heart failure use of captopril should be under specialist supervision. Myocardial infarction: _Short-term (4 weeks) treatment_: Captopril is indicated in any clinically stable patient within the first 24 hours of an infarction. _Long-term prevention of symptomatic heart failure:_ Captopril is indicated in clinically stable patients with asymptomatic and symptomatic left ventricular dysfunction (ejection fraction < 40%) following myocardial infarction to improve survival, delay the onset of symptomatic heart failure, reduce hospitalisations for heart failure and reduce recurrent myocardial infarction and coronary revascularisation procedures. Before starting therapy, cardiac function should be determined by radionuclide ventriculography or echocardiography. Type I Diabetic Nephropathy: Captopril is indicated in insulin dependent diabetics for the treatment of macroproteinuric diabetic nephropathy (microalbuminuria greater than 30 mg/day) Đọc toàn bộ tài liệu