AVAR LS- sodium sulfacetamide, sulfur aerosol, foam

Quốc gia: Hoa Kỳ

Ngôn ngữ: Tiếng Anh

Nguồn: NLM (National Library of Medicine)

Thành phần hoạt chất:

SULFACETAMIDE SODIUM (UNII: 4NRT660KJQ) (SULFACETAMIDE - UNII:4965G3J0F5), SULFUR (UNII: 70FD1KFU70) (SULFUR - UNII:70FD1KFU70)

Sẵn có từ:

Mission Pharmacal Company

INN (Tên quốc tế):

SULFACETAMIDE SODIUM

Thành phần:

SULFACETAMIDE SODIUM 100 mg in 1 g

Tuyến hành chính:

TOPICAL

Loại thuốc theo toa:

PRESCRIPTION DRUG

Chỉ dẫn điều trị:

This product is indicated for use in the topical control of acne vulgaris, acne rosacea and seborrheic dermatitis. This product is contraindicated in persons with known or suspected hypersensitivity to any of the ingredients of the product. This product is not to be used by patients with kidney disease. General: Nonsusceptible organisms, including fungi, may proliferate with the use of this preparation. Although rare, sensitivity to sodium sulfacetamide may occur. Therefore, caution and careful supervision should be observed when prescribing this drug for patients who may be prone to hypersensitivity to topical sulfonamides. If the use of this product produces signs of hypersensitivity or other untoward reactions, discontinue use of the preparation. Patients should be carefully observed for possible local irritation or sensitization during long-term therapy. Systemic toxic reactions such as agranulocytosis, acute hemolytic anemia, purpura hemorrhagica, drug fever, jaundice and contact dermatitis indicate hyp

Tóm tắt sản phẩm:

This product is supplied in the following size(s): 3.5 oz. (100 g) cans, NDC 0178-0653-01 To report a serious adverse event or obtain product information, call 1-800-298-1087. Manufactured for: MISSION PHARMACAL COMPANY San Antonio, TX 78230 1355

Tình trạng ủy quyền:

unapproved drug other

Đặc tính sản phẩm

AVAR LS- SODIUM SULFACETAMIDE, SULFUR AEROSOL, FOAM
MISSION PHARMACAL COMPANY
_Disclaimer: This drug has not been found by FDA to be safe and
effective, and this labeling has not been_
_approved by FDA. For further information about unapproved drugs,
click here._
----------
AVAR LS (SODIUM SULFACETAMIDE 10%, SULFUR 2%) FOAM
RX ONLY
FOR EXTERNAL USE ONLY. NOT FOR OPHTHALMIC USE.
DESCRIPTION:
Each gram contains 100 mg of sodium sulfacetamide and 20 mg of
colloidal sulfur in a vehicle
consisting of: benzyl alcohol, cetyl alcohol, fragrance, glyceryl
stearate (and) PEG-100 stearate,
magnesium aluminum silicate, phenoxyethanol, propylene glycol,
purified water, sodium lauryl sulfate,
sodium magnesium silicate, sodium thiosulfate, stearyl alcohol, and
xanthan gum. This product also
contains tetrafluoroethane (propellant).
Sodium sulfacetamide is a sulfonamide with antibacterial activity
while sulfur acts as a keratolytic
agent. Sodium sulfacetamide is C
H
N
NaO
S·H
O with molecular weight of 254.24. Chemically,
sodium sulfacetamide is N-[(4-aminophenyl) sulfonyl]-acetamide,
monosodium salt, monohydrate. The
structural formula is:
Sodium sulfacetamide is an odorless, white,crystalline powder with a
bitter taste. It is freely soluble in
water, sparingly soluble in alcohol, while practically insoluble in
benzene, in chloroform and in ether.
CLINICAL PHARMACOLOGY:
Sodium sulfacetamide exerts a bacteriostatic effect against
sulfonamide sensitive Gram-positive and
Gram-negative microorganisms commonly isolated from secondary
cutaneous pyogenic infections. It
acts by restricting the synthesis of folic acid required by bacteria
for growth, by its competition with
para-aminobenzoic acid. There is no clinical data available on the
degree and rate of systemic
absorption of this product when applied to the skin or scalp. However,
significant absorption of sodium
sulfacetamide through the skin has been reported.
The following in vitro data is available but the clinical significance
is unknown. Organisms that show
susceptibility to