SILDANIL PHT 20

Страна: Австралія

мова: англійська

Джерело: Department of Health (Therapeutic Goods Administration)

Активний інгредієнт:

Sildenafil citrate

Доступна з:

Accord Healthcare Pty Ltd

Клас:

Medicine Registered

інформаційний буклет

SILDANIL PHT 20  
CONSUMER MEDICINE INFORMATION

        Version: 1.0

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                                         Page: 1
of 4

SILDANIL PHT 20  
(SILDENAFIL (AS CITRATE) 20 MG FILM-COATED TABLETS) 
CONSUMER MEDICINE INFORMATION 

WHAT IS IN THIS LEAFLET  

This leaflet answers some common 
questions about Sildanil PHT 20.  

It does not contain all the available 
information.  

It does not take the place of talking 
to your doctor or pharmacist. 

All medicines have risks and 
benefits. Your doctor has weighed 
the risks of your taking Sildanil PHT 
20 against the benefits they expect it 
will have for you. 

It should be used only under strict 
medical supervision. 

IF YOU HAVE ANY CONCERNS ABOUT 
TAKING THIS MEDICINE, ASK YOUR 
DOCTOR OR PHARMACIST. 

KEEP THIS LEAFLET WITH THE MEDICINE. 

You may need to read it again. 

WHAT SILDANIL PHT 20 IS 
USED FOR  

Sildanil PHT 20 is used to treat 
pulmonary arterial hypertension 
(high blood pressure in the blood 
vessels in the lungs). Sildanil PHT 
20 brings down the blood pressure 
by relaxing these vessels. Sildanil 
PHT 20 tablet contain the active 
ingredient sildenafil (present as 
sildenafil citrate) which belongs to a 
group of medicines called 
phosphodiesterase type 5 inhibitors. 

ASK YOUR DOCTOR IF YOU HAVE ANY 
QUESTIONS ABOUT WHY SILDANIL PHT 
20  HAS BEEN PRESCRIBED FOR YOU. 

This medicine is available only with 
a doctor's prescription. 

BEFORE YOU TAKE SILDANIL 
PHT

Характеристики продукта

Sildanil PHT 20 (Sildenafil (as citrate) 20 mg film-coated
Tablets)                            
Version 1.0 

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                     Page 1 of 25

PRODUCT INFORMATION 
SILDANIL PHT 20  
(SILDENAFIL (AS CITRATE) 20 MG FILM-COATED TABLETS) 

NAME OF THE MEDICINE  
Sildenafil (as citrate) 

DESCRIPTION 

Sildenafil 20 mg, an oral therapy for pulmonary arterial
hypertension, is the citrate salt of 
sildenafil, a selective inhibitor of cyclic guanosine monophosphate
(cGMP)-specific 
phosphodiesterase type-5 (PDE5).  
SILDENAFIL CITRATE IS
1-[4-ETHOXY-3-(6,7-DIHYDRO-1-METHYL-7-OXO-3-PROPYL-1H-
PYRAZOLO[4,3-D]PYRIMIDIN-5-YL)PHENYLSULPHONYL]-4-METHYLPIPERAZINE
CITRATE. CAS 
NUMBER 171,599-83-0.   

The empirical formula for sildenafil citrate is C
22
H
30
N
6
O
4
S.C
6
H
8
0
7

Sildenafil citrate has the following structural formula:- 

Sildenafil citrate is an off-white, crystalline powder with a
molecular weight of 666.7. Its 
aqueous solubility is equivalent to 2.6 mg sildenafil per mL at
25°C.  

In addition to sildenafil citrate, each sildenafil tablet
contains the following inactive 
ingredients: microcrystalline cellulose, calcium hydrogen phosphate
anhydrous, 
croscarmellose sodium, hypromellose, magnesium stearate. The
 film-coating contains 
opadry II complete film coating system 31K58643 white (ARTG
No.107652), which 
consists of hypromellose, titanium dioxide, lactose, glycerol
triacetate. 

Sildanil PHT 20 (Sildenafil (as citrate) 20 mg film-coated
Tablets)                            
Version 1.0 

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                     Page 2 of 25

PHARMACOLOGY  

PHARMACOLOGICA