Страна: ПАР
мова: англійська
Джерело: South African Health Products Regulatory Authority (SAHPRA)
Intramed
METYPRESOL 125 mg Powder for Injection METYPRESOL 500 mg Powder for Injection METYPRESOL 1 g Powder for Injection INTRAMED METYPRESOL DILUENT (2 mL; 7,5 mL; 15 mL) vial SCHEDULING STATUS: S4 PROPRIETARY NAME: (and dosage form): METYPRESOL 125 mg Powder for Injection METYPRESOL 500 mg Powder for Injection METYPRESOL 1 g Powder for Injection INTRAMED METYPRESOL DILUENT (2 mL; 7,5 mL; 15 mL) vial COMPOSITION: Metypresol 125 mg contains methylprednisolone sodium succinate equivalent to methylprednisolone 125 mg. Metypresol 500 mg contains methyl prednisolone sodium succinate equivalent to methylprednisolone 500 mg. Metypresol 1 g contains methylprednisolone sodium succinate equivalent to methylprednisolone 1 g Intramed Metypresol Diluent contains Water for Injection 2 mL (7,5 mL; 15 mL). PHARMACOLOGICAL CLASSIFICATION: A.21.5.1 Corticosteroids and analogues. PHARMACOLOGICAL ACTION: Metypresol is a glucocorticoid with an anti-inflammatory potency of 5 relative to hydrocortisone while its sodium retaining potency is 0,5 compared with hydrocortisone. It has an intermediate duration of action (12 to 36 hours). INDICATIONS: – Serious acute allergic reaction as supplement to primary therapy such as adrenaline. – Status asthmaticus. – Cerebral oedema associated with neoplasms. – Suppression of graft rejection reactions following transplantation. – Malignant haematologic diseases (e.g. acute lymphoblastic leukaemia) in conjunction with antineoplastic agents. – Haematologic dyscrasias (e.g. acute autoimmune hemalytic anaemia idiopathic thrombocytopenic purpurea). CONTRA-INDICATIONS: – Acute infections including herpes simplex and herpes zoster, ulceration of the eye, varicella, vaccinia. – Psychoses. – Peptic ulcer. – Cushing's syndrome. – Osteoporosis. – Severe psychoneuroses. – Vaccination wit Прочитайте повний документ