Lexapro

Страна: Австралія

мова: англійська

Джерело: Department of Health (Therapeutic Goods Administration)

Активний інгредієнт:

Escitalopram oxalate

Доступна з:

Lundbeck Australia Pty Ltd

Клас:

Medicine Registered

інформаційний буклет

LEXAPRO
®

(LEX-A-PRO)
_Escitalopram oxalate (ES-sigh-talo-pram OX-a-late)_
CONSUMER MEDICINE INFORMATION (CMI)

WHAT IS IN THIS LEAFLET
This leaflet contains answers to some
common questions about Lexapro.
It does not contain all the information
that is known about Lexapro. It does
not take the place of talking to your
doctor or pharmacist.
All medicines have risks and
benefits. Your doctor has weighed
the risk of you using this medicine
against the benefits he/she expects it
will have for you.
IF YOU HAVE ANY CONCERNS ABOUT
USING THIS MEDICINE, ASK YOUR
DOCTOR OR PHARMACIST.
KEEP THIS LEAFLET WITH THE MEDICINE.
You may need to read it again.
WHAT LEXAPRO IS USED
FOR
Lexapro is used to treat depression.
It belongs to a group of medicines
called selective serotonin reuptake
inhibitors (SSRIs). They are thought
to work by their actions on brain
chemicals called amines which are
involved in controlling mood.
Depression is longer lasting or more
severe than the "low moods"
everyone has from time to time due
to the stress of everyday life. It is
thought to be caused by a chemical
imbalance in parts of the brain. This
imbalance affects your whole body
and can cause emotional and physical
symptoms such as feeling low in
spirit, loss of interest in activities,
being unable to enjoy life, poor
appetite or overeating, disturbed
sleep, often waking up early, loss of
sex drive, lack of energy and feeling
guilty over nothing.
Lexapro corrects this chemical
imbalance and may help relieve the
symptoms of depression.
Lexapro may also be used to treat
patients who may avoid and/or are
fearful of social situations.
Lexapro may also be used to treat
patients who have excessive anxiety
and worry.
Lexapro may also be used to treat
irrational fears or obsessional
behaviour (obsessive-compulsive
disorder). Obsessive-compulsive
disorder involves having both
obsessions and compulsions.
Obsessions are unwanted thoughts
that occur over and over again.
Compulsions are the ongoing need to
repeat certain actions as a result of

Характеристики продукта

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PRODUCT INFORMATION 

LEXAPRO
®
 FILM-COATED TABLETS 
LEXAPRO
®
 ORAL SOLUTION 

NAME OF THE MEDICINE 

Escitalopram oxalate 

Chemical name: 
S(+)-1-(3-dimethylaminopropyl)-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-carbonitrile 
hydrogen oxalate.   

CAS number: 
219861-08-2 
Molecular formula: 
C
20
H
21
FN
2
O, C
2
H
2
O
4

Molecular weight: 
414.42 

Structural formula: 

NC
O
CH
2
CH
2
CH
2
N(CH
3
)
2
     , HOOCCOOH
F

DESCRIPTION 

Escitalopram is the active enantiomer (S-enantiomer) of citalopram.  Escitalopram oxalate 
is a fine white to yellow, crystalline material. 

Escitalopram  oxalate  is  sparingly  soluble  in  water,  slightly  soluble  in  acetone,  soluble  in 
ethanol and freely soluble in methanol.  No polymorphic forms
have been detected. 

Lexapro 10 mg tablets are oval, white, scored, film-
coated tablets marked with "E” and “L" 
on one side.  
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Lexapro 20 mg tablets are oval, white, scored, film-
coated tablets marked with "E” and “N" 
on one side. 

Lexapro  tablets  contain  the  following  excipients:  cellulose  -  microcrystalline,  silica  - 
colloidal  anhydrous,  talc  -  purified,  croscarmellose  sodium,  magnesium  stearate, 
hypromellose, macrogol 400 and titanium dioxide. 

Lexapro  oral  solution  is  a  clear,  nearly  colourless  to  yellowish  solution.    It  contains  the 
following_ _excipients: sodium hydroxide and purified water. 

PHARMACOLOGY 

Pharmacological actions 

Biochemical and behavioural studies have shown that escitalopram is a potent inhibitor of 
serotonin (5-HT)-uptake (_in vitro_ IC
50
 2nM). 

The  antidepressant  action