Lercanidipine 10mg tablets

Страна: Велика Британія

мова: англійська

Джерело: MHRA (Medicines & Healthcare Products Regulatory Agency)

Активний інгредієнт:

Lercanidipine hydrochloride

Доступна з:

Accord-UK Ltd

Код атс:

C08CA13

ІПН (Міжнародна Ім'я):

Lercanidipine hydrochloride

Дозування:

10mg

Фармацевтична форма:

Oral tablet

Адміністрація маршрут:

Oral

Клас:

No Controlled Drug Status

Тип рецепту:

Valid as a prescribable product

Огляд продуктів:

BNF: 02060200; GTIN: 5012617019431

інформаційний буклет

READ ALL OF THIS LEAFLET CAREFULLY BEFORE
YOU START USING THIS MEDICINE BECAUSE IT
CONTAINS IMPORTANT INFORMATION FOR YOU.
•
Keep this leaflet. You may need to read
it again.
•
If you have any further questions, ask
your doctor or pharmacist.
•
This medicine has been prescribed for
you only. Do not pass it on to others. It
may harm them, even if their signs of
illness are the same as yours.
•
If you get any side effects, talk to your
doctor or pharmacist. This includes any
possible side effects not listed in this
leaflet. See section 4.
WHAT IS IN THIS LEAFLET:
1
WHAT LERCANIDIPINE HYDROCHLORIDE
TABLETS ARE AND WHAT THEY ARE USED
FOR
2
WHAT YOU NEED TO KNOW BEFORE YOU
TAKE
3
HOW TO TAKE
4
POSSIBLE SIDE EFFECTS
5
HOW TO STORE
6
CONTENTS OF THE PACK AND OTHER
INFORMATION
1
WHAT LERCANIDIPINE HYDROCHLORIDE
TABLETS ARE AND WHAT THEY ARE USED
FOR
Lercanidipine belongs to a group of
medicines called calcium channel blockers
that block the entry of calcium into the
muscle cells of the heart and the blood
vessels that carry blood away from the
heart (the arteries). It is the entry of calcium
into these cells that causes the heart to
contract and arteries to narrow. By blocking
the entry of calcium, calcium channel
blockers decrease contraction of the heart
and dilate (widen) the arteries, and the
blood pressure is reduced.
Lercanidipine has been prescribed to you
to treat your high blood pressure, also
known as hypertension.
2
WHAT YOU NEED TO KNOW BEFORE YOU
TAKE
DO NOT TAKE LERCANIDIPINE IF YOU:
• are ALLERGIC to lercanidipine or any of the
other ingredients of this medicine (listed
in section 6).
• have HAD ALLERGIC REACTIONS to
medicines that are closely related to
Lercanidipine hydrochloride tablets (such
as amlodipine, nicardipine, felodipine,
isradipine, nifedipine or lacidipine)
• are suffering from certain HEART diseases:
• uncontrolled cardiac failure
• an obstruction to flow of blood from the
heart
• unstable angina (angina at rest or
progressively increasing)
• have had a heart attack le

Характеристики продукта

OBJECT 1
LERCANIDIPINE HYDROCHLORIDE 10 MG FILM-COATED
TABLET
Summary of Product Characteristics Updated 21-May-2018 | Accord-UK Ltd
1. Name of the medicinal product
Lercanidipine hydrochloride 10 mg film-coated tablet
2. Qualitative and quantitative composition
One film-coated tablet contains 10 mg lercanidipine hydrochloride,
equivalent to 9.4mg lercanidipine.
Excipient with known effect:
Lercanidipine hydrochloride 10 mg film-coated tablet: Lactose
monohydrate 30 mg
For the full list of excipients, see section 6.1.
3. Pharmaceutical form
Film-coated tablet
Lercanidipine hydrochloride 10 mg film-coated tablet: Yellow, round,
biconvex 6.5 mm film-coated
tablets, scored on one side, marked 'L' on the other side.
The score line is only to facilitate breaking for ease of swallowing
and not to divide into equal doses.
4. Clinical particulars
4.1 Therapeutic indications
Lercanidipine hydrochloride is indicated for the treatment of mild to
moderate essential hypertension.
4.2 Posology and method of administration
Posology
Route of administration: For oral use.
The recommended dosage is 10 mg orally once a day at least 15 minutes
before meals; the dose may be
increased to 20 mg depending on the individual patient's response.
Dose titration should be gradual, because it may take about 2 weeks
before the maximal antihypertensive
effect is apparent.
Some individuals, not adequately controlled on a single
antihypertensive agent, may benefit from the
addition of lercandipine to therapy with a beta-adrenoreceptor
blocking drug, a diuretic
(hydrochlorothiazide) or an angiotensin converting enzyme inhibitor.
Since the dose-response curve is steep with a plateau at doses between
20-30 mg, it is unlikely that
efficacy will be improved by higher doses; whereas side effects may
increase.
Elderly
Although the pharmacokinetic data and clinical experience suggest that
no adjustment of the daily dosage
is required, special care should be exercised when initiating
treatment in the elderly.
_Paediatric population_
Lercanidipine is not r