IODOQUINOL 1% - HYDROCORTISONE ACETATE 2% - ALOE POLYSACCHARIDES 1% gel

Страна: США

мова: англійська

Джерело: NLM (National Library of Medicine)

Активний інгредієнт:

IODOQUINOL (UNII: 63W7IE88K8) (IODOQUINOL - UNII:63W7IE88K8), HYDROCORTISONE ACETATE (UNII: 3X7931PO74) (HYDROCORTISONE - UNII:WI4X0X7BPJ), ALOE VERA LEAF POLYSACCHARIDES (UNII: W21O437517) (ALOE VERA LEAF - UNII:ZY81Z83H0X)

Доступна з:

Seton Pharmaceuticals

Адміністрація маршрут:

TOPICAL

Тип рецепту:

PRESCRIPTION DRUG

Терапевтичні свідчення:

Based on a review of a related drug by the National Research Council and subsequent FDA classification for that drug, the indications are as follows: “Possibly” Effective: Contact or atopic dermatitis; impetiginized eczema; nummular eczema; endogenous chronic infectious dermatitis; stasis dermatitis; pyoderma; nuchal eczema and chronic eczematoid otitis externa; acne urticata; localized or disseminated neurodermatitis; lichen simplex chronicus; anogenital pruritus (vulvae, scroti, ani); folliculitis; bacterial dermatoses; mycotic dermatoses such as tinea (capitis, cruris, corporis, pedis); monliasis; intertrigo. Final classification of the less-than-effective indications requires further investigation. This product is contraindicated in persons with known or suspected hypersensitivity to any of the ingredients of the product.

Огляд продуктів:

This product is supplied in the following size(s): 48 g Tube, NDC 13925-174-48

Статус Авторизація:

unapproved drug other

Характеристики продукта

IODOQUINOL 1% - HYDROCORTISONE ACETATE 2% - ALOE POLYSACCHARIDES
1%- IODOQUINOL 1% - HYDROCORTISONE ACETATE 2% - ALOE POLYSACCHARIDES
1% GEL
SETON PHARMACEUTICALS
_Disclaimer: This drug has not been found by FDA to be safe and
effective, and this labeling has not been_
_approved by FDA. For further information about unapproved drugs,
click here._
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IODOQUINOL 1% - HYDROCORTISONE ACETATE 2% ALOE POLYSACCHARIDES 1% GEL
RX ONLY
DESCRIPTION:
Each gram contains 20 mg of hydrocortisone acetate, 10 mg of
iodoquinol and 10 mg of aloe
polysaccharide in a vehicle consisting of: amino methylpropanol 95%,
benzyl alcohol, carbomer, citric
acid anhydrous, D&C yellow #10, FD&C blue #1, glycerin, glyceryl
polymethacrylate, magnesium
aluminum silicate, palmitoyl oligopeptide, PPG-20 methyl glucose
ether, propylene glycol, purified
water and SD Alcohol 40B.
Hydrocortisone acetate is an anti-inflammatory and antipruritic agent.
Chemically, hydrocortisone
acetate is [Pregn-4-ene-3, 20-dione, 21-(acetyloxy)-11, 17-dihydroxy-,
(11-ß)-] with the molecular
formula (C23H32O6) and is represented by the following structural
formula:
Iodoquinol is an antifungal and antibacterial agent. Chemically,
Iodoquinol is [5,7-diiodo-8-quinolinol]
with the molecular formula (C9H5I2NO) and is represented by the
following structural formula:
Aloe Polysaccharides are a concentrated, water soluble subcomponent of
Aloe Vera with a mono-sugar
ratio of Man : Gal : Glc: 40 : 1.4 : 1.0, linkage of 1-4 ß - linkage,
O-Acetyl group of 25% of sugar units,
and specific rotation of [α]D= -3.98˚ at 23.2˚ C. Average molecular
weight is 80,000 daltons.
Chemically, Aloe Polysaccharides is represented by the following
structural formula:
CLINICAL PHARMACOLOGY:
Hydrocortisone acetate has anti-inflammatory, antipruritic and
vasoconstrictive properties. While the
mechanism of anti-inflammatory activity is unclear, there is evidence
to suggest that a recognizable
correlation exists between vasoconstrictor potency and therapeutic
efficacy in humans. Iodoquinol h