IBUFEN SYRUP

Страна: Малайзія

мова: англійська

Джерело: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)

Активний інгредієнт:

IBUPROFEN

Доступна з:

DYNAPHARM (M) SDN BHD

ІПН (Міжнародна Ім'я):

IBUPROFEN

Одиниць в упаковці:

100 mL; 60 mL; 60 mL; 100 mL

Виробник:

DYNAPHARM (M) SDN BHD

інформаційний буклет

Consumer Medication Information Leaflet (RiMUP)
IBUFEN SYRUP/TABLET
Ibuprofen (100mg/5ml, 200mg, 400mg)
Page 1 of 2
What is in this leaflet
1.
What IBUFEN is used for
2.
How IBUFEN works
3.
Before you use IBUFEN
4.
How to use IBUFEN
5.
While you are using it
6.
Side effects
7.
Storage and Disposal of
IBUFEN
8.
Product Description
9.
Manufacturer and Product
Registration Holder
10.
Date of revision
What IBUFEN is used for
IBUFEN is used for:
-
Relief of the signs and symptoms
of rheumatoid arthritis and
osteoarthritis.
-
Relief of mild to moderate pain.
-
Antigout agent to treat non-
rheumatic inflammatory
conditions.
-
To relieve menstrual pain.
How IBUFEN works
Ibuprofen stops the body from
producing large amounts of
prostaglandins when you have an
illness or injury. As Ibuprofen
blocks the production of
prostaglandins, it works at the site
of pain to help relieve pain and
reduce inflammation.
Before you use IBUFEN
-
When you must not use it
If you have hypersensitive to
Aspirin or Ibuprofen.
Pregnancy and lactation
Do not take IBUFEN if you are
pregnant, trying to get pregnant or
think you may be pregnant.
Do not take IBUFEN if you are
breast- feeding. Ask your doctor or
pharmacist for advice before taking
any medicine.
-
Before you start use it
Tell your doctor if you
-
Have bleeding disorders,
cardiovascular disease, peptic
ulceration or a history of such
ulceration
-
If you are receiving coumarin
anticoagulants
-
If you are patients with
hypertension, asthma, breathing
difficulty, heart failure and kidney
failure.
-
Taking other medicines
Tell your doctor if you are taking
oral anticoagulants, thiazide
diuretics or any other medicines,
including any that you buy without a
prescription from a pharmacy,
supermarket or health food shop.
How to use IBUFEN
-
How much to use
IBUFEN SYRUP
Children: 20 mg / kg body weight
per day in divided doses. This can
be achieved as follows:
1 - 2 years: One 2.5 ml spoonful (50
mg) three to four times daily.
3 - 7 years: One 5 ml spoonful (100
mg) three to four times daily.
8 -

Характеристики продукта

IBUFEN SYRUP
MAL19984404AZ
DESCRIPTION:
SYRUP
Colour
:
Colourless
Flavour
:
Apple
EACH 5 ML OF SYRUP CONTAINS:
Ibuprofen ................... 100 mg
Preservatives: Sodium Benzoate 0.1% w/v, Methyl Paraben 0.1% w/v &
Propyl Paraben 0.01% w/v.
PHARMACODYNAMICS:
Analgesic action: It may block out pain impulse generation via a
peripheral action which may involve inhibition of
the synthesis of prostaglandins, and possibly inhibition of the
synthesis or action of other substances which sensitise
pain receptors to mechanical or chemical stimulation.
Anti-inflammatory action: It may act peripherally in inflamed tissue,
probably by inhibiting the synthesis and/or
actions of other local mediators of the inflammatory response.
Antipyretic action: Acts centrally on the hypothalamic heat-regulating
centre to produce peripheral vasodilation,
resulting in increased blood flow through the skin, sweating, and heat
loss. The central action probably involves
reduction of prostaglandin activity in the hypothalamus.
PHARMACOKINETICS:
Ibuprofen is absorbed from the gastrointestinal tract and peak plasma
concentrations occur about 1 to 2 hours after
ingestion. Ibuprofen is extensively bound to plasma proteins and has a
half-life of about 2 hours. It is rapidly
excreted in the urine mainly as metabolites and their conjugates.
About 1% is excreted in urine as unchanged
Ibuprofen and about 14% as conjugated Ibuprofen.
INDICATIONS:
It is indicated for fever and pain in children. Also for its analgesic
and anti-inflammatory effects in the treatment of
rheumatoid arthritis (including juvenile rheumatoid arthritis) and
also soft tissue injuries such as sprains and strains.
It is also indicated for the relief of mild to moderate pain such as
dental and post-operative pain and for
symptomatic relief of headache including migraine headache.
RECOMMENDED DOSE:
Children:
20 mg/kg body weight per day in divided doses. This can be achieved as
follows:
1 – 2 years
:
One 2.5 ml spoonful (50 mg) three to four times daily.
3 – 7 years
:
One 5 ml spoon