ELONZA 100 MG TABLET

Страна: Малайзія

мова: англійська

Джерело: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)

Активний інгредієнт:

SILDENAFIL CITRATE

Доступна з:

MEDISPEC (M) SDN.BHD

ІПН (Міжнародна Ім'я):

SILDENAFIL CITRATE

Одиниць в упаковці:

20 Tablet Tablets; 4 Tablet Tablets

Виробник:

Unison Laboratories Co. Ltd.

інформаційний буклет

ELONZA 100MG TABLET
Sildenafil citrate eq. to sildenafil (100mg)
_CONSUMER MEDICATION INFORMATION LEAFLET (RIMUP)_
1
WHAT IS IN THIS LEAFLET
1.
What Elonza is used for
2.
How Elonza works
3.
Before you use Elonza
4.
How to use Elonza
5.
While you are using it
6.
Side effects
7. Storage and Disposal of Elonza
8.
Product Description
9.
Manufacturer and Product Registration
Holder
10. Date of revision
WHAT ELONZA IS USED FOR
Elonza is used in treatment of men with
erectile dysfunction, which is the inability
to achieve or maintain a penile erection
sufficient
for
satisfactory
sexual
performance.
In
order
for
Elonza to
be
effective, sexual stimulation is required.
HOW ELONZA WORKS
Sidenafil belongs to a group of medicines
called phosphodiesterase type 5 inhibitors.
Sildenafil is an oral therapy for erectile
dysfunction. In the natural setting, i.e. with
sexual
s t i m u l a t i o n ,
it
restores
imp aired erectile function by increasing
blood flow to the penis. It works by helping
to relax the blood vessels in your penis,
allowing blood to flow into your penis when
you get sexually excited. Sildenafil will only
help you to get an erection if you are sexually
stimulated.
BEFORE YOU USE ELONZA
_- When you must not use it_

If
you are allergic (hypersensitive) to
Sildenafil citrate

If
you are allergic (hypersensitive) to
any of the other ingredients of Elonza

If y o u are t a k i n g m ed icines called
“Nitrates”
 Nitrates are usually given for relief of
angina pectoris (or “chest pain”)
 Sildenafil if taken in combination
with nitrates may lead to a dangerous
fall in your blood pressure.

If you are using any of the medicines
known as Nitric oxide donors such as
Amyl
nitrite
(“poppers”),
as
the
combination
may
also
lead
to
a
dangerous fall in your blood pressure.

If you have a severe heart problem

If you have a severe liver disorder
 Sildenafil should not be used unless
when clearly indicated and prescribed by
doctor. Your doctor may decide to give a
lower dose for you.

If

Характеристики продукта

ELONZA 100_Insert_Front,Back_IEMY 0042_By...DA 15/06/2023
ELONZA 100 mg
IEMY 0042
w. 15.5 x L 25 cm.
Wood Free Paper (¡ÃдÒɻ͹´)
60 g (0.08 mm.)
Each film coated tablet contains:
SILDENAFIL CITRATE EQ. TO
SILDENAFIL 100 MG
ERECTILE DYSFUNCTION DRUG
PRODUCT DESCRIPTION:
Royal blue, rhombic, biconvex, film coated tablet with engraved 100 on
one side and scored on the other
MECHANISM OF ACTION:
_PHARMACOLOGY_
Sildenafil is an oral therapy for erectile dysfunction. In the natural
setting, i.e. with sexual stimulation, it restores impaired erectile
function
by increasing blood flow to the penis.
The physiological mechanism responsible for erection of the penis
involves the release of nitric oxide (NO) in the corpus cavernosum
during sexual stimulation. Nitric oxide then activates the enzyme
guanylate cyclase, which results in increased levels of cyclic
guanosine
monophosphate (cGMP), producing smooth muscle relaxation in the corpus
cavernosum and allowing inflow of blood. Sildenafil is a potent
and selective inhibitor of cGMP specific phosphodiesterase type 5
(PDE5) in the corpus cavernosum, where PDE5 is responsible for
degradation of cGMP. Sildenafil has a peripheral site of action on
erections. Sildenafil has no direct relaxant effect on isolated human
corpus
cavernosum but potently enhances the relaxant effect of NO on this
tissue. When the NO/cGMP pathway is activated, as occurs with sexual
stimulation, inhibition of PDE5 by Sildenafil results in increased
corpus cavernosum levels of cGMP. Therefore sexual stimulation is
required in order for Sildenafil to produce its intended beneficial
pharmacological effects.
Studies
_in vitro_
have shown that Sildenafil is selective for PDE5, which is involved in
the erection process. Its effect is more potent on
PDE5 than on other known phosphodiesterases. There is a 10-fold
selectivity over PDE6 which is involved in the phototransduction
pathway
in the retina. At maximum recommended doses, there is an 80-fold
selectivity over PDE1, and over 700-fold over PDE 2,