DESOWEN CREAM 0.05%

Страна: Сінгапур

мова: англійська

Джерело: HSA (Health Sciences Authority)

Активний інгредієнт:

DESONIDE

Доступна з:

GALDERMA SINGAPORE PRIVATE LIMITED

Код атс:

D07AB08

Дозування:

0.05%

Фармацевтична форма:

CREAM

Склад:

DESONIDE 0.05%

Адміністрація маршрут:

TOPICAL

Тип рецепту:

Prescription Only

Виробник:

LABORATOIRES GALDERMA

Статус Авторизація:

ACTIVE

Дата Авторизація:

1995-07-04

інформаційний буклет

DESONIDE
DESOWEN
®
0.05% (0.5MG/G) 
COR TICOSTEROID
PMS 432 U + Tramé
ATTENTION FICHIER EN NOIR MAIS IMPRESSION EN 432U
FORMULATION:
Each gram of Desowen Cream contains 0.5 mg of desonide microdispersed
in a compatible vehicle buffered to the pH range of normal
skin. It contains Potassium sorbate, Polysorbate 60, Sorbic acid,
Propyl gallate, Wax SE, Beeswax synthetic, Stearic acid, Isopropyl
palmitate, Propylene glycol, Sodium hydroxide solution, Citric acid
anhydrous solution and Purified water.
Each gram of Desowen Lotion contains 0.5 mg of desonide in a lotion
vehicle consisting of Tetrasodium EDTA tetrahydrate, Methyl
parahydroxybenzoate, Sodium lauryl sulfate, Liquid paraffin 15-25
mPa.s, Glyceryl monostearate SE, Sorbitan monostearate, Cetyl
alcohol, Stearyl alcohol, Propyl parahydroxybenzoate, Propylene
glycol, Sodium hydroxide solution, Citric acid anhydrous solution and
Purified water.
CLINICAL PHARMACOLOGY:
Topical corticosteroids share anti-inflammatory, anti-pruritic and
vasoconstrictive actions.
The mechanism of anti-inflammatory activity of the topical
corticosteroids is unclear. Various laboratory methods, including
vasoconstrictor assays are used to compare and predict potencies
and/or clinical efficacies of the topical corticosteroids. There is
some
evidence to suggest that a recognizable correlation exists between
vasoconstrictor potency and therapeutic efficacy in man.
PHARMACOKINETICS:
The extent of percutaneous absorption of topical corticosteroids is
determined by many factors including the vehicle, the integrity of
the epidermal barrier and the use of occlusive dressings. Topical
corticosteroids can be absorbed from normal intact skin. Inflammation
and/or other disease processes in the skin increase percutaneous
absorption. Occlusive dressings substantially increase the
percutaneous absorption of topical corticosteroids. Thus, occlusive
dressings may be a valuable therapeutic adjunct for treatment of
resistant dermatoses (see Dosage and Administration). 
Once absorbed through the skin,

Характеристики продукта

C O R T I
C O S T E R O I
D
NOTICE RECTO 180x315
PLAN n° MT.09.DRA.0352.R02.2
Product code: P2XXXX-X
Product description: DESOWEN LOT 60
Market: EX2
Article: Leaflet
Flat size: 180x315
Font size: 10 pt
Fold size: 180x26,25
Pharmacode: TBD
DIELINES
_GRAPHIC DESIGNER: Guillaume ANDRÉ_
_INDUSTRIALIZATION DEPARTMENT_
_LABORATOIRES GALDERMA - Z.I. Galderma - 74540 ALBY-SUR-CHÉRAN -
FRANCE_
PMS 432U
D E S O N I D E
D E S O W E N
®
0.05% (0.5MG/G)
FORMULATION:
Each gram of Desowen Cream contains 0.5 mg of desonide microdispersed
in a compatible vehicle buffered to the pH range of normal skin. It
contains
Potassium sorbate, Polysorbate 60, Sorbic acid, Propyl gallate, Wax
SE, Beeswax synthetic, Stearic acid, Isopropyl palmitate, Propylene
glycol, Sodium
hydroxide solution, Citric acid anhydrous solution and Purified water.
Each
gram
of
Desowen
Lotion
contains
0.5
mg
of
desonide
in
a
lotion
vehicle
consisting
of
Tetrasodium
EDTA
tetrahydrate,
Methyl
parahydroxybenzoate, Sodium lauryl sulfate, Liquid paraffin 15-25
mPa.s, Glyceryl monostearate SE, Sorbitan monostearate, Cetyl alcohol,
Stearyl
alcohol, Propyl parahydroxybenzoate, Propylene glycol, Sodium
hydroxide solution, Citric acid anhydrous solution and Purified water.
CLINICAL PHARMACOLOGY:
Topical corticosteroids share anti-inflammatory, anti-pruritic and
vasoconstrictive actions.
The mechanism of anti-inflammatory activity of the topical
corticosteroids is unclear. Various laboratory methods, including
vasoconstrictor assays are
used to compare and predict potencies and/or clinical efficacies of
the topical corticosteroids. There is some evidence to suggest that a
recognizable
correlation exists between vasoconstrictor potency and therapeutic
efficacy in man.
PHARMACOKINETICS:
The extent of percutaneous absorption of topical corticosteroids is
determined by many factors including the vehicle, the integrity of the
epidermal
barrier and the use of occlusive dressings. Topical corticosteroids
can be absorbed from normal intact skin. Inflammation and/or other
diseas