Страна: Австралія
мова: англійська
Джерело: Department of Health (Therapeutic Goods Administration)
Amoxycillin trihydrate; Potassium clavulanate
Sandoz Pty Ltd
Medicine Registered
_Product Information _ _ _ _Page 1 _ _Curam 125/31.25 amoxycillin/clavulanic acid 125+31.25mg/5mL Powder for Suspension _ _12/2011 _ _Sandoz Pty Ltd _ _ _ _ _ _ _ _ _ PRODUCT INFORMATION CURAM 125/31.25 POWDER FOR SUSPENSION NAME OF THE MEDICINE _ _ _Chemical name_: (2_S_,5_R_,6_R_)-6-[[(2_R_)-2-Amino-2-(4-hydroxyphenyl)acetyl]amino]- 3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid trihydrate._ _ _Generic name: Amoxycillin trihydrate _ _Chemical structure: _ _ _ _ _ _ _ _CAS [61336-70-7] _ _Empirical formula: _C 16 H 19 N 3 O 5 S.3H 2 O MW: 419.5 _ _ _ _ _ _ _Chemical name:_ potassium (2_R_,3_Z_,5_R_)-3-(2-hydroxyethylidene)-7-oxo-4-oxa-1- azabicyclo[3.2.0]heptane-2-carboxylate. _Generic name: potassium clavulanate _ _Chemical structure: _ _ _ _ _ _ _ _CAS [61177-45-5] _ _Empirical formula: _C 8 H 8 KNO 5 _ _ _ _ MW:_ _237.3 DESCRIPTION Curam 125/31.25 is a combination product containing the semisynthetic antibiotic, amoxycillin (as the trihydrate) and the beta-lactamase inhibitor, clavulanic acid (as the potassium salt). _Product Information _ _ _ _Page 2 _ _Curam 125/31.25 amoxycillin/clavulanic acid 125+31.25mg/5mL Powder for Suspension _ _12/2011 _ _Sandoz Pty Ltd _ _ _ _ _ _ _ Amoxycillin is susceptible to hydrolysis by beta-lactamases. Clavulanic acid is produced by the fermentation of _Streptomyces clavuligerus_. It is an irreversible inhibitor of many beta-lactamase enzymes except type 1 (Richmond). It is a beta-lactam compound with only weak antibacterial activity. _Excipients: _ Lemon Flavouring 15.02.0598, Peach-Apricot Flavouring 26F22, Citric acid anhydrous, Sodium citrate anhydrous, A Прочитайте повний документ