Chemmart Metformin

Страна: Австралія

мова: англійська

Джерело: Department of Health (Therapeutic Goods Administration)

Активний інгредієнт:

Metformin hydrochloride

Доступна з:

Apotex Pty Ltd

Клас:

Medicine Registered

інформаційний буклет

CHEMMART METFORMIN
500/850/1000

_Contains the active ingredient, metformin (met-FOR-min)
hydrochloride_
CONSUMER MEDICINE INFORMATION

WHAT IS IN THIS LEAFLET
READ THIS LEAFLET CAREFULLY BEFORE
TAKING YOUR MEDICINE.
This leaflet answers some common
questions about metformin. It does
not contain all the available
information. It does not take the
place of talking to your doctor,
pharmacist or diabetes educator.
The information in this leaflet was
last updated on the date listed on the
last page. More recent information on
this medicine may be available.
ASK YOUR DOCTOR OR PHARMACIST:
•
if there is anything you do not
understand in this leaflet,
•
if you are worried about taking
your medicine, or
•
to obtain the most up-to-date
information.
All medicines have risks and
benefits. Your doctor has weighed
the risks of you using this medicine
against the benefits they expected it
will have for you.
Pharmaceutical companies cannot
give you medical advice or an
individual diagnosis.
Keep this leaflet with your medicine.
You may need to read it again.
WHAT THIS MEDICINE IS
USED FOR
The name of your medicine is
Chemmart Metformin 500, 850 or
1000. It contains the active
ingredient, metformin (as metformin
hydrochloride).
There are two types of diabetes:
•
type 1, also called insulin
dependent diabetes
•
type 2, also called non-insulin
dependent diabetes mellitus
(NIDDM) or maturity onset
diabetes.
Chemmart Metformin 500, 850 or
1000 can be used in type 2 diabetes
in adults and children over 10 years
of age. It is especially useful in those
who are overweight, when diet and
exercise are not enough to lower high
blood glucose levels
(hyperglycaemia). For adult patients,
metformin can be used alone, or in
combination with other oral diabetic
medicines or in combination with
insulin in insulin requiring type 2
diabetes.
Ask your doctor if you have any
questions about why this medicine
has been prescribed for you. Your
doctor may have prescribed this
medicine for another reason.
This medicine is availab

Характеристики продукта

 
Product Information 
– Australia 
Chemmart Metformin 500/850/1000 Tablets 
Page 1 
CHEMMART METFORMIN 500 TABLETS 
CHEMMART METFORMIN 850 TABLETS 
CHEMMART METFORMIN 1000 TABLETS 

NAME OF THE MEDICINE 
Metformin hydrochloride. 

Chemical Name:  

1,1-dimethylbiguanide hydrochloride 

Structural Formula: 

N
H
2
N
H
N
CH
3
CH
3
NH
NH
,  HCl

Molecular Formula:  

C
4
H
11
N
5
.HCl  

Molecular Weight:  

165.6 

CAS Registry No:  

1115-70-4 

DESCRIPTION 
Metformin hydrochloride is a white, crystalline powder which is almost odourless and hygroscopic. It is 
freely soluble in water, slightly soluble in ethanol  (96%) and practically insoluble in chloroform and in 
ether. 

PHARMACOLOGY 
Metformin  is  an  oral  biguanide  hypoglycaemic  agent.  It  causes  an  increased  peripheral  uptake  of 
glucose by increasing the biological efficiency of available exogenous or
endogenous insulin. 

The  mode  of  action  of  metformin  may  be  linked  to  an  increase  of  insulin  sensitivity.  It  does  not 
stimulate  insulin  release  but  does  require  the  presence  of  insulin  to  exert  its  anti-hyperglycaemic 
effect.  Possible  mechanisms  of  action  include  inhibition  of  gluconeogenesis  in  the  liver,  delay  in 
glucose absorption from the
gastrointestinal tract and an increase in peripheral uptake
of glucose. 

Metformin  has  an  antiketogenic  activity  which  is  comparable,  though  somewhat  inferior,  to  insulin 
itself.  Metformin  lowers  both  basal  and  post-prandial  blood  glucose  in  diabetic  patients  but  does  not 
cause hypoglycaemia in either diabetics or normal individuals. 

PHARMACOKINETICS 
Absorption 
After  oral  administration,  metformin