Страна: Канада
мова: англійська
Джерело: Health Canada
CEFUROXIME (CEFUROXIME SODIUM)
FRESENIUS KABI CANADA LTD
J01DC02
CEFUROXIME
1.5G
POWDER FOR SOLUTION
CEFUROXIME (CEFUROXIME SODIUM) 1.5G
INTRAVENOUS
50ML
Prescription
SECOND GENERATION CEPHALOSPORINS
Active ingredient group (AIG) number: 0122448007; AHFS:
APPROVED
2006-10-05
Cefuroxime for Injection, USP – Product Monograph Page 1 of 36_ _ PRODUCT MONOGRAPH PR CEFUROXIME FOR INJECTION, USP 750 mg / 15 mL vials 1.5 g / 50 mL vials 7.5 g / 100 mL Pharmacy Bulk Package Vial Antibiotic FRESENIUS KABI CANADA LTD. Date of Preparation: 165 Galaxy Blvd, Suite 100 April 17, 2020 Toronto, ON M9W 0C8 Control No.: 233970 Cefuroxime for Injection, USP – Product Monograph Page 2 of 36 PRODUCT MONOGRAPH PR CEFUROXIME FOR INJECTION, USP 750 mg / 15 mL vials 1.5 g / 50 mL vials 7.5 g / 100 mL Pharmacy Bulk Package Vial THERAPEUTIC CLASSIFICATION Antibiotic ACTION AND CLINICAL PHARMACOLOGY _In vitro_ studies demonstrate that the bactericidal action of cefuroxime results from inhibition of bacterial cell wall synthesis by inhibiting the transpeptidase and carboxypeptidase enzymes. INDICATIONS AND CLINICAL USES TREATMENT Cefuroxime for Injection, USP may be indicated for the treatment of patients with infections caused by susceptible strains of the designated organisms in the following diseases: LOWER RESPIRATORY TRACT INFECTIONS: Pneumonia caused by _Streptococcus pneumoniae, Haemophilus influenzae_ including ampicillin- resistant strains, _Klebsiella_ species, _Staphylococcus_ _aureus_ including ampicillin-resistant (but not methicillin-resistant) strains, _Streptococcus_ _pyogenes_, and _Escherichia coli. _ URINARY TRACT INFECTIONS: Caused by _Escherichia coli_, and _Klebsiella _species. SOFT TISSUE INFECTIONS: Caused by _Staphylococcus aureus, _including ampicillin-resistant (but not methicillin-resistant) strains, _Streptococcus pyogenes, Escherichia coli_, and_ Klebsiella_ species. MENINGITIS: Caused by _Staphylococcus_ _aureus_ including ampicillin-resistant (but not methicillin-resistant) strains, _Streptococcus pneumoniae, Haemophilus influenzae_, and _Neisseria_ _meningitidis_. GONORRHEA: Caused by _Neisseria_ _gonorrhoeae_ including ampicillin-resistant strains. Cefuroxime for Injection, USP – Product Monograph Page 3 of 36 BONE AND JOINT INFECTIONS: Caused by _Staphylococcus aureus_ (p Прочитайте повний документ