Axcel Cefuroxime-500mg Tablet

Страна: Малайзія

мова: англійська

Джерело: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)

Активний інгредієнт:

CEFUROXIME AXETIL

Доступна з:

KOTRA PHARMA (M) SDN. BHD.

ІПН (Міжнародна Ім'я):

CEFUROXIME AXETIL

Одиниць в упаковці:

10 Tablets; 100 Tablets

Виробник:

KOTRA PHARMA (M) SDN. BHD.

інформаційний буклет

AXCEL CEFUROXIME-500MG TABLET
Cefuroxime Axetil equivalent to Cefuroxime 500mg
1
_CONSUMER MEDICATION INFORMATION LEAFLET (RIMUP) _
WHAT IS IN THIS LEAFLET
1.
What Axcel Cefuroxime-500mg
Tablet is used for.
2.
How Axcel Cefuroxime-500mg
Tablet works.
3.
Before
you
use
Axcel
Cefuroxime-500mg Tablet.
4.
How to use Axcel Cefuroxime-
500mg Tablet.
5.
While you are using it.
6.
Side effects.
7.
Storage
and
disposal
of
Axcel
Cefuroxime-500mg Tablet.
8.
Product description.
9.
Manufacturer
and
Product
Registration Holder.
10.
Date of revision.
WHAT
AXCEL
CEFUROXIME-500MG
TABLET IS USED FOR
Axcel Cefuroxime-500mg Tablet is
used for:
•
Upper respiratory tract infections
for example; ear, nose and throat
infections, such as otitis media,
sinusitis,
tonsillitis
and
pharyngitis.
•
Lower
respiratory
tract
infections
for
example;
pneumonia
(lung
infection),
acute
bronchitis,
and
acute
exacerbations
of
chronic
bronchitis.
•
Genito-urinary
tract
infections
for
example;
pyelonephritis
(inflammation
of
the
kidney),
cystitis(inflammation
of
the
bladder)and
urethritis
(inflammation of the urethra).
•
Skin
and
soft
tissue
infections
for
example;
furunculosis,
pyoderma and impetigo.
•
Gonorrhoea
(sexually
transmitted
infection),
acute
uncomplicated
gonococcal
urethritis,
and
cervicitis
(inflammation of the cervix).
HOW
AXCEL
CEFUROXIME-500MG
TABLET WORK
Cefuroxime
inhibits
bacterial
cell
wall synthesis following attachment
to penicillin binding proteins (PBPs).
This results in the interruption of cell
wall
(peptidoglycan)
biosynthesis,
which leads to bacterial cell lysis and
death.
BEFORE YOU USE AXCEL CEFUROXIME-
500MG TABLET
−
_When you must not use it _
Do
not
take
Axcel
Cefuroxime-
500mg Tablet:
•
If
you
are
allergic
to
cephalosporin antibiotic
Some
of
the
symptoms
of allergic
reaction
may
include
skin
rash,
itchiness,
shortness
of
breath,
swelling of the face, lips or tongue.
Special care should be given when
taking
Axcel
Cefuroxime-500mg
Tablet if:
•
You are allergic to penicillin or
other beta lactam antibiotic

Характеристики продукта

COMPOSITION:
Each tablet contains
Cefuroxime Axetil
equivalent to Cefuroxime 500mg
PRESENTATION:
White to off white, biconvex, capsule shape
tablet with a scoreline on one side and B032 on
other side.
INDICATIONS:
Cefuroxime
axetil
is
an
oral
prodrug
of
the
bactericidal cephalosporin antibiotic cefuroxime,
which is resistant to most β-lactamases and is
active against a wide range of Gram-positive and
Gram-negative organisms. It is indicated for the
treatment of infections caused by susceptible
bacteria. Susceptibility to Cefuroxime axetil will
vary
with
geography
and
time
and
local
susceptibility data should be consulted where
available
(See
Pharmacological
properties,
Pharmacodynamics).
This
indicated
for
the
treatment
of
infections
caused
by
sensitive
bacteria which are including :
• Upper respiratory tract infections for example;
ear, nose and throat infections, such as otitis
media, sinusitis, tonsillitis and pharyngitis.
• Lower respiratory tract infections for example;
pneumonia,
acute
bronchitis,
and
acute
exacerbations of chronic bronchitis.
• Genito-urinary tract infections for example;
pyelonephritis, cystitis and urethritis.
• Skin and soft tissue infections for example;
furunculosis, pyoderma and impetigo.
• Gonorrhoea, acute uncomplicated gonococcal
urethritis, and cervicitis.
Cefuroxime is also available as the sodium salt
for parenteral administration. This permits the
use
of
sequential
therapy
with
the
same
antibiotic, when a change from parenteral to oral
therapy
is
clinically
indicated.
Where
appropriate, Axcel Cefuroxime-500mg Tablet is
effective when used following initial parenteral
Vaxcel Cefuroxime Injection (cefuroxime sodium)
in
the
treatment
of
pneumonia
and
acute
exacerbations of chronic bronchitis.
PHARMACOLOGY:
Mechanism of Action:
Cefuroxime
axetil
undergoes
hydrolysis
by
esterase
enzymes
to
the
active
antibiotic,
cefuroxime. Cefuroxime inhibits bacterial cell
wall synthesis following attachment to penicillin
binding
proteins
(PBPs).
This
results
in
the interruption of cel