AMPICILLIN- ampicillin sodium injection, powder, for solution

Страна: США

мова: англійська

Джерело: NLM (National Library of Medicine)

Активний інгредієнт:

AMPICILLIN SODIUM (UNII: JFN36L5S8K) (AMPICILLIN - UNII:7C782967RD)

Доступна з:

Sandoz GmbH

Адміністрація маршрут:

INTRAVENOUS

Тип рецепту:

PRESCRIPTION DRUG

Терапевтичні свідчення:

Ampicillin for Injection, USP is indicated in the treatment of infections caused by susceptible strains of the designated organisms in the following conditions: Respiratory Tract Infections caused by Streptococcus pneumoniae , Staphylococcus aureus (penicillinase and nonpenicillinase-producing), H. influenzae , and Group A beta-hemolytic streptococci. Bacterial Meningitis caused by E. coli , Group B Streptococci , and other Gram-negative bacteria (Listeria monocytogenes, N. meningitidis ). The addition of an aminoglycoside with ampicillin may increase its effectiveness against Gram-negative bacteria. Septicemia and Endocarditis caused by susceptible Gram-positive organisms including Streptococcus spp., penicillin G-susceptible staphylococci, and enterococci. Gram-negative sepsis caused by E. coli, Proteus mirabilis and Salmonella spp. responds to ampicillin. Endocarditis due to enterococcal strains usually respond to intravenous therapy. The addition of an aminoglycoside may enhance the effectiveness o

Огляд продуктів:

Ampicillin for Injection, USP, Pharmacy Bulk Package, contains ampicillin sodium equivalent to 10 grams ampicillin per bottle. NDC 43858-115-95 10 gram Pharmacy Bulk Package – Packaged in 10s Store at 20° to 25°C (68° to 77°F) [see USP Controlled Room Temperature]. Protect the constituted solution from freezing.

Статус Авторизація:

Abbreviated New Drug Application

Характеристики продукта

AMPICILLIN- AMPICILLIN SODIUM INJECTION, POWDER, FOR SOLUTION
SANDOZ GMBH
----------
AMPICILLIN FOR INJECTION, USP
PHARMACY BULK PACKAGE – NOT FOR DIRECT INFUSION
To reduce the development of drug-resistant bacteria and maintain the
effectiveness of ampicillin and
other antibacterial drugs, ampicillin should be used only to treat or
prevent infections that are proven or
strongly suspected to be caused by bacteria.
DESCRIPTION
Ampicillin for Injection, USP the monosodium salt of
[2S-[2α,5α,6β(S*)]]-6-
[(aminophenylacetyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic
acid, is
a synthetic penicillin for intravenous use. The pharmacy bulk package
contains sterile ampicillin sodium
equivalent to 10 grams ampicillin. It is an antibacterial agent with a
broad spectrum of bactericidal
activity against both penicillin-susceptible Gram-positive organisms
and many common Gram-negative
pathogens.
Ampicillin for Injection, USP is a white to cream-tinged, crystalline
powder. The reconstituted solution
is clear, colorless and free from visible particulates.
Each Pharmacy Bulk Package bottle contains ampicillin sodium
equivalent to 10 grams of ampicillin.
The sodium content is 65.8 mg (2.9 mEq) per one gram ampicillin.
A pharmacy bulk package is a container of a sterile preparation for
parenteral use that contains many
single doses. The contents of this pharmacy bulk package are intended
for use by a pharmacy admixture
service for addition to suitable parenteral fluids in the preparation
of admixtures for intravenous
infusion. (See DOSAGE AND ADMINISTRATION, DIRECTIONS FOR PROPER USE OF
PHARMACY BULK
PACKAGE).
It has the following molecular structure:
The molecular formula is C
H N NaO S, and the molecular weight is 371.39. The pH range of the
reconstituted solution is 8 to 10.
CLINICAL PHARMACOLOGY
Ampicillin for Injection, USP diffuses readily into most body tissues
and fluids. However, penetration
into the cerebrospinal fluid and brain occurs only when the meninges
are inflamed. Ampicillin is
e