Zynomax Tablet 250mg

Ülke: Malezya

Dil: İngilizce

Kaynak: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)

Aktif bileşen:

AZITHROMYCIN DIHYDRATE

Mevcut itibaren:

Duopharma Marketing Sdn. Bhd.

INN (International Adı):

AZITHROMYCIN DIHYDRATE

Paketteki üniteler:

10tablet Tablets; 90tablet Tablets; 30tablet Tablets; 100tablet Tablets; 6tablet Tablets

Tarafından üretildi:

DUOPHARMA MANUFACTURING (BANGI) SDN BHD

Bilgilendirme broşürü

_Consumer Medication Information Leaflet (RiMUP)_
1
ZYNOMAX 250MG TABLET
Azithromycin 250mg
WHAT IS IN THIS LEAFLET
1.
WHAT ZYNOMAX 250MG
TABLET IS USED FOR
2.
HOW ZYNOMAX 250MG
TABLET WORKS
3.
BEFORE YOU USE ZYNOMAX
250MG TABLET
4.
HOW TO USE ZYNOMAX
250MG TABLET
5.
WHILE YOU ARE USING IT
6.
SIDE EFFECTS
7.
STORAGE AND DISPOSAL OF
ZYNOMAX 250MG TABLET
8.
PRODUCT DESCRIPTION
9.
MANUFACTURER AND PRODUCT
REGISTRATION HOLDER
10.
DATE OF REVISION
1. WHAT ZYNOMAX 250MG TABLET
IS
USED FOR
Zynomax
250mg
Tablet
is used
to
treat
infections
caused
by
certain
bacteria
and
other
micro-organisms
which include:
•
Chest,
throat,
ear
or
nasal
infections
(such
as
bronchitis,
pneumonia, tonsillitis, pharyngitis,
acute otitis media and sinusitis)
•
Skin
and
soft
tissue
infections
(such as an abscess or boil)
•
Sexually-transmitted
diseases
caused
by
organisms
called
Chlamydia,
Haemophilus
or
Gonorrhoea.
2.
HOW
ZYNOMAX
250MG
TABLET
WORKS
Zynomax
250mg
Tablet
is
an
antibiotic, which belongs to a group
of
medicines
called
azalides.
The
azalides are a sub-class of a group of
antibiotics called macrolides.
Zynomax
250mg
Tablet
works
by
killing
or
stopping
the
growth
of
bacteria causing your infection.
Zynomax
250mg
Tablet
will
not
work against viral infections such as
colds or influenza.
Ask
your
doctor
if
you
have
any
questions
about
why
Zynomax
250mg Tablet has been prescribed for
you.
Your
doctor
may
have
prescribed it for another reason.
Zynomax
250mg
Tablet
is
only
available with a doctor's prescription.
This medicine is not addictive.
3. BEFORE YOU USE ZYNOMAX 250MG
TABLET
WHEN YOU MUST NOT TAKE IT
Do not take Zynomax 250mg Tablet
if you are allergic to:
i.
azithromycin
ii.
any other macrolide or ketolide
antibiotics
(e.g.,
clarithromycin,
erythromycin,
roxithromycin,
telithromycin)
iii.
any of the ingredients listed at
the end of this leaflet.
Symptoms of an allergic reaction may
include shortness of breath, wheezing
or
difficulty
breathing;
swelling
of
the face, lips, tongue or other parts of
the body; rash, itching or hiv

Ürün özellikleri

A. Tablet 250mg
Azithromycin 250mg
B. Powder for Oral Suspension 200mg/5ml
Azithromycin 200mg/5ml
CLINICAL PHARMACOLOGY
Pharmacodynamic Properties
Pharmacotherapeutic group: Macrolides, ATC code
J01FA10
.
Azithromycin is the first of a subclass of macrolide antibiotics,
known as azalides, and is chemically different from
erythromycin. Chemically it is derived by insertion of a nitrogen atom
into the lactone ring of erythromycin A. The chemical
name of azithromycin is 9-deoxy-9a-aza-9a-methyl-9a-homoerythromycin
A. The molecular weight is 749.0.
Azithromycin binds to the 23S rRNA of the 50S ribosomal subunit. It
blocks protein synthesis by inhibiting the
transpeptidation/translocation step of protein synthesis and by
inhibiting the assembly of the 50S ribosomal subunit.
Antibacterial spectrum
The susceptibility of bacterial species to azithromycin is shown
below.
The prevalence of acquired resistance may vary geographically and with
time for selected species and local information on
resistance is desirable, particularly when treating severe infections.
As necessary, expert advice should be sought when the
local prevalence of resistance is such that the utility of the agent
in at least some types of infections is questionable.
In-vitro susceptibility data do not always correlate with clinical
results.
Organisms that are commonly susceptible to azithromycin include:
Aerobic and facultative gram-positive bacteria
(erythromycin-susceptible isolates): _S. aureus, Streptococcus
agalactiae,* S. _
_pneumoniae,* Streptococcus pyogenes,_* other b-hemolytic streptococci
(Groups C, F, G) and viridans streptococci.
Macrolide-resistant isolates are encountered relatively frequently
among aerobic and facultative gram-positive bacteria, in
particular among methicillin-resistant _S. aureus_ (MRSA) and
penicillin-resistant _S. pneumoniae _(PRSP).
Aerobic and facultative gram-negative bacteria: _ Bordetella
pertussis, Haemophilus ducreyi,_*_ Haemophilus influenzae,_*
_Haemophilus parainfluenzae,_*_ Legionella pneumophila, Moraxella