SILATIO 20

Ülke: Avustralya

Dil: İngilizce

Kaynak: Department of Health (Therapeutic Goods Administration)

Aktif bileşen:

Sildenafil citrate

Mevcut itibaren:

Accord Healthcare Pty Ltd

Sınıf:

Medicine Registered

Bilgilendirme broşürü

SILATIO 20  
CONSUMER MEDICINE INFORMATION

        Version: 1.0

-2012-                                          

                                         Page: 1
of 4

SILATIO 20  
(SILDENAFIL (AS CITRATE) 20 MG FILM-COATED TABLETS) 
CONSUMER MEDICINE INFORMATION 

WHAT IS IN THIS LEAFLET  

This leaflet answers some common 
questions about Silatio 20.  

It does not contain all the available 
information.  

It does not take the place of talking 
to your doctor or pharmacist. 

All medicines have risks and 
benefits. Your doctor has weighed 
the risks of your taking Silatio 20 
against the benefits they expect it 
will have for you. 

It should be used only under strict 
medical supervision. 

IF YOU HAVE ANY CONCERNS ABOUT 
TAKING THIS MEDICINE, ASK YOUR 
DOCTOR OR PHARMACIST. 

KEEP THIS LEAFLET WITH THE MEDICINE. 

You may need to read it again. 

WHAT SILATIO 20 IS USED 
FOR  

Silatio 20 is used to treat pulmonary 
arterial hypertension (high blood 
pressure in the blood vessels in the 
lungs). Silatio 20 brings down the 
blood pressure by relaxing these 
vessels. Silatio 20 tablet contain the 
active ingredient sildenafil (present 
as sildenafil citrate) which belongs to 
a group of medicines called 
phosphodiesterase type 5 inhibitors. 

ASK YOUR DOCTOR IF YOU HAVE ANY 
QUESTIONS ABOUT WHY SILATIO 20  HAS 
BEEN PRESCRIBED FOR YOU. 

This medicine is available only with 
a doctor's prescription. 

BEFORE YOU TAKE SILATIO 
20  

WHEN YOU MUST NOT TAKE IT 

DO NOT 

Ürün özellikleri

Silatio 20 (Sildenafil (as
citrate) 20 mg film-coated Tablets)                 

Version 1.0 

-2012-                                          

                     Page 1 of 25

PRODUCT INFORMATION 
SILATIO 20 
(SILDENAFIL (AS CITRATE) 20 MG FILM-COATED TABLETS) 

NAME OF THE MEDICINE  
Sildenafil (as citrate) 

DESCRIPTION 

Sildenafil 20 mg, an oral therapy for pulmonary arterial
hypertension, is the citrate salt of 
sildenafil, a selective inhibitor of cyclic guanosine monophosphate
(cGMP)-specific 
phosphodiesterase type-5 (PDE5).  
SILDENAFIL CITRATE IS
1-[4-ETHOXY-3-(6,7-DIHYDRO-1-METHYL-7-OXO-3-PROPYL-1H-
PYRAZOLO[4,3-D]PYRIMIDIN-5-YL)PHENYLSULPHONYL]-4-METHYLPIPERAZINE
CITRATE. CAS 
NUMBER 171,599-83-0.   

The empirical formula for sildenafil citrate is C
22
H
30
N
6
O
4
S.C
6
H
8
0
7

Sildenafil citrate has the following structural formula:- 

Sildenafil citrate is an off-white, crystalline powder with a
molecular weight of 666.7. Its 
aqueous solubility is equivalent to 2.6 mg sildenafil per mL at
25°C.  

In addition to sildenafil citrate, each sildenafil tablet
contains the following inactive 
ingredients: microcrystalline cellulose, calcium hydrogen phosphate
anhydrous, 
croscarmellose sodium, hypromellose, magnesium stearate. The
 film-coating contains 
opadry II complete film coating system 31K58643 white (ARTG
No.107652) which 
consists of hypromellose, titanium dioxide, lactose, glycerol
triacetate. 

Silatio 20 (Sildenafil (as
citrate) 20 mg film-coated Tablets)                 

Version 1.0 

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                     Page 2 of 25

PHARMACOLOGY  

PHARMACOLOGICAL ACTIONS 

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