Retorin Powder for Suspension 125mg 5ml

Ülke: Malezya

Dil: İngilizce

Kaynak: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)

Aktif bileşen:

ERYTHROMYCIN ETHYLSUCCINATE

Mevcut itibaren:

SM PHARMACEUTICALS SDN. BHD.

INN (International Adı):

ERYTHROMYCIN ETHYLSUCCINATE

Paketteki üniteler:

100 ml

Tarafından üretildi:

SM PHARMACEUTICALS SDN. BHD.

Bilgilendirme broşürü

CONSUMER MEDICATION INFORMATION LEAFLET (RIMUP)
RETORIN POWDER FOR SUSPENSION
_ERYTHROMYCIN ETHYL SUCCINATE SUSPENSION 125MG/5ML _
_________________________________________________________________________________________________________________
______________________________________________________________________________________________________
1
WHAT IN THIS LEAFLET
1. What is Retorin used for
2.How Retorin works
3.Before you use Retorin
4.How to use Retorin
5.While you are using it
6.Side Effects
7.Storage and Disposal of Retorin
8.Products Descriptions
9.Manufacturer and Product Registration
Holder
10.Date of revision WHAT IS RETORIN USED FOR
•
Respiratory Tract Infections
•
Skin and Soft Tissue Infections
•
Eye/Ear infections
•
Oral infections
•
Gastro-intestinal Infections
•
Other infections
Gonorrhoea, syphilis, urethritis
diphtheria, pertussis.
HOW RETORIN WORKS
used to treat bacterial infections.
BEFORE YOU USE RETORIN
When you must not use it
Should not be used in patients with a
known history of allergy to this drug.
Before you start use it
Tell your doctor if you have liver problem,
pregnant, going to get pregnant or breast
feeding.
Taking other medicine
Talk to your doctor/pharmacist if you are
taking any medicine including those you buy
without a prescription. Some of the
medicines may interact with Retorin
if taken together, such as :
•
terfenadine or mizolastine (used to
treat Allergies such as hayfever)
•
domperidone (used to treat nausea
and vomiting)
•
pimozide, amisulpride, (used to treat
mental problems)
•
ergotamine or dihydroergotamine
(for migraine)
•
cisapride (for stomach disorders)
•
statins (used to help lower cholesterol
levels e.g. simvastatin)
•
Tolterodine(to treat frequent urination)
Your doctor or pharmacist may have
more information on medicines to be
careful with or to avoid while taking
this medication. HOW TO USE RETORIN
How much to use
Adults and Children over 8 Years:
For mild to moderate infections 2 g daily in
divided doses up to 4 g daily in sev

Ürün özellikleri

SM PHARMACEUTICALS SDN. BHD.
RETORIN POWDER FOR SUSPENSION 125MG/5ML
_ _
DESCRIPTION:
Almost pink to pink colour dry powder, forming pink colour suspension
on
reconstitution with water.
COMPOSITION:
Each
5ml
of
the
Reconstituted
suspension
contains:
Erythromycin
Ethyl
Succinate
Equivalent
to
Erythromycin
125mg
and
Preservative
Sodium
Benzoate 2.08mg.
PHARMACODYNAMICS:
Pharmacotherapeutic group: Macrolides, Lincosamides and
Streptogramins,
Macrolides.
Mechanism of action
Erythromycin exerts its antimicrobial action by binding to the 50S
ribosomal
sub-unit of susceptible microorganisms and suppresses protein
synthesis.
Erythromycin is usually active against most strains of the following
organisms
both in vitro and in clinical infections
.
Gram
positive
bacteria
-
Listeria
monocytogenes,
Corynebacterium
diphtheriae (as an adjunct to antitoxin), Staphylococci spp,
Streptococci spp
(including Enterococci).
Gram negative bacteria - Haemophilus influenzae, Neisseria
meningitidis,
Neisseria
gonorrhoeae,
Legionella
pneumophila,
Moraxella
(Branhamella)
catarrhalis, Bordetella pertussis, Campylobacter spp.
Mycoplasma - Mycoplasma pneumoniae, Ureaplasma urealyticum.
Other organisms - Treponema pallidum, Chlamydia spp, Clostridia spp,
L-
forms, the agents causing trachoma and lymphogranuloma venereum.
Note: The majority of strains of Haemophilus influenzae are
susceptible to the
concentrations reached after ordinary doses
PHARMACOKINETICS:
Absorption is facilitated if the stomach is empty.
Peak blood levels normally occur within 1 hour of dosing of
erythromycin
ethyl succinate granules. The elimination half-life is approximately 2
hours.
Doses may be administered 2, 3 or 4 times a day.
Erythromycin ethyl succinate is less susceptible than erythromycin to
the
adverse effect of gastric acid. It is absorbed from the small
intestine. It is
widely distributed throughout body tissues. Little metabolism occurs
and only
about 5% is excreted in the urine. It is excreted principally by the
liver.
The drug is not removed by either perit