Ülke: Avustralya
Dil: İngilizce
Kaynak: Department of Health (Therapeutic Goods Administration)
Paroxetine hydrochloride
Aspen Pharma Pty Ltd
Medicine Registered
EXTINE- Consumer Medicine Information Page 1 of 5 EXTINE paroxetine (as hydrochloride) CONSUMER MEDICINE INFORMATION (CMI) WHAT IS IN THIS LEAFLET This leaflet answers some common questions about EXTINE. It does not contain all of the available information. It does not take the place of talking to your doctor or pharmacist. All medicines have benefits and risks. Your doctor has weighed the risks of you taking EXTINE against the benefits they expect it will have for you. TALK TO YOUR DOCTOR OR PHARMACIST IF YOU HAVE ANY CONCERNS ABOUT TAKING THIS MEDICINE. KEEP THIS LEAFLET WITH YOUR MEDICINE. You may need to read it again. WHAT EXTINE IS USED FOR EXTINE is used to: treat depression treat irrational fears or obsessional behaviour prevent panic attacks treat patients who avoid or are fearful of social situations treat patients with excessive anxiety and worry, and who feel irritable, restless, and/or tense in the muscles treat repetitive and distressing recollections of a past traumatic event. Depression is longer lasting or more severe than the 'low moods' that everyone has from time to time. It is thought to be caused by a chemical imbalance in parts of the brain. This imbalance affects your whole body and can cause emotional and physical symptoms. You may feel low in spirit, lose interest in usual activities, be unable to enjoy life, have poor appetite or over eat, have disturbed sleep, often wake up early, have low energy and feel guilty over nothing. EXTINE corrects the chemical imbalance and so helps relieving the symptoms of depression. EXTINE belongs to a group of medicines called selective serotonin reuptake inhibitor (SSRI) antidepressants. They are thought Belgenin tamamını okuyun
EXTINE- Product Information Page 1 of 21 Extine PRODUCT INFORMATION NAME OF THE MEDICINE Paroxetine (as hydrochloride). The chemical name for paroxetine hydrochloride is (3S,4R)-3-[(1,3- benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine hydrochloride. Its structural formula is: H N H H O O O F HCl 3 4 C 19 H 20 NO 3 F∙HCl Molecular weight: 365.83 Cas No.: 78246-49-8 DESCRIPTION Paroxetine hydrochloride is a white to off-white crystalline powder that is slightly soluble in water and sparingly soluble in ethanol and dichloromethane. It has a chemical structure unrelated to other selective serotonin reuptake inhibitors or to tricyclic, tetracyclic or other available antidepressant agents. It is the hydrochloride salt of a phenylpiperidine compound. Extine tablets come in three strengths and contain either 10 mg, 20 mg or 30 mg of paroxetine (as the hydrochloride). The tablets also contain the following excipients: magnesium stearate, sodium starch glycollate, mannitol, microcrystalline cellulose, Eudragit E100 (ARTG No. 1753) and Opadry Yellow AMB 80W12287 (ARTG No. 11507; 10 mg only) or Opadry White AMB OY-B-28920 (ARTG No. 4271; 20 mg only) or Opadry Blue AMB 80W90536 (ARTG No. 11506; 30 mg only). The tablets are gluten free. PHARMACOLOGY Paroxetine is a potent and selective inhibitor of 5-hydroxytryptamine (5HT, serotonin) uptake and its antidepressant action and efficacy in the treatment of Obsessive Compulsive Disorder (OCD), Panic Disorder, Social Anxiety Disorder, Social Phobia, Generalised Anxiety Disorder and Posttraumatic Stress Disorder are thought to be related to its specific inhibit Belgenin tamamını okuyun