EPINEPHRINE- epinephrine injection, solution

Ülke: ABD

Dil: İngilizce

Kaynak: NLM (National Library of Medicine)

Aktif bileşen:

EPINEPHRINE (UNII: YKH834O4BH) (EPINEPHRINE - UNII:YKH834O4BH)

Mevcut itibaren:

A-S Medication Solutions

Uygulama yolu:

INTRAMUSCULAR

Reçete türü:

PRESCRIPTION DRUG

Terapötik endikasyonlar:

Epinephrine is used to relieve respiratory distress due to bronchospasm, to provide rapid relief of hypersensitivity reactions to drugs and other allergens, and to prolong the action of anesthetics. Its cardiac effects may be of use in restoring cardiac rhythm in cardiac arrest due to various causes, but it is not used in cardiac failure or in hemorrhagic, traumatic, or cardiogenic shock. Epinephrine is used as a hemostatic agent. It is also used in treating mucosal congestion of hay fever, rhinitis, and acute sinusitis; to relieve bronchial asthmatic paroxysms; in syncope due to complete heart block or carotid sinus hypersensitivity; for symptomatic relief of serum sickness, urticaria, angioneurotic edema; for resuscitation in cardiac arrest following anesthetic accidents; in simple (open angle) glaucoma; for relaxation of uterine musculature and to inhibit uterine contractions. Epinephrine Injection can be utilized to prolong the action of anesthetics used in local and regional anesthesia. Epinephrine is co

Ürün özeti:

Product: 50090-0418 NDC: 50090-0418-0 1 mL in a AMPULE NDC: 50090-0418-1 1 mL in a AMPULE

Yetkilendirme durumu:

unapproved drug other

Ürün özellikleri

EPINEPHRINE- EPINEPHRINE INJECTION, SOLUTION
A-S MEDICATION SOLUTIONS
_Disclaimer: This drug has not been found by FDA to be safe and
effective, and this labeling has not been_
_approved by FDA. For further information about unapproved drugs,
click here._
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EPINEPHRINE
INJECTION, USP
1 mg/mL
AMPUL
PROTECT FROM LIGHT UNTIL READY TO USE.
Rx only
_DESCRIPTION_
Epinephrine Injection, USP 1 mg/mL is a sterile, nonpyrogenic
solution. Each mL contains epinephrine 1
mg; sodium chloride 9 mg; sodium metabisulfite 0.9 mg added. May
contain hydrochloric acid for pH
adjustment.
The solution contains no bacteriostat or antimicrobial agent. It is
administered by the following routes:
intravenous, intracardiac (left ventricular chamber), via endotracheal
tube into the bronchial tree,
subcutaneous or intramuscular.
Epinephrine, USP is a sympathomimetic (adrenergic) agent designated
chemically as 4-[1-hydroxy-2
(methylamino) ethyl]-1,2 benzenediol, a white, microcrystalline
powder. It has the following structural
formula:
Sodium Chloride, USP is chemically designated NaCl, a white,
crystalline compound freely soluble in
water.
_CLINICAL PHARMACOLOGY_
The actions of epinephrine resemble the effects of stimulation of
adrenergic nerves. To a variable
degree it acts on both alpha and beta receptor sites of sympathetic
effector cells. Its most prominent
actions are on the beta receptors of the heart, vascular and other
smooth muscle. When given by rapid
intravenous injection, it produces a rapid rise in blood pressure,
mainly systolic, by (1) direct
stimulation of cardiac muscle which increases the strength of
ventricular contraction, (2) increasing the
heart rate and (3) constriction of the arterioles in the skin, mucosa
and splanchnic areas of the
circulation.
When given by slow intravenous injection epinephrine usually produces
only a moderate rise in systolic
and a fall in diastolic pressure. Although some increase in pulse
pressure occurs, there is usually no
great elevation in mean blood pressure. Accordingly, the compe