Ülke: Güney Afrika
Dil: İngilizce
Kaynak: South African Health Products Regulatory Authority (SAHPRA)
Lennon
CYCLIMYCIN-50 CAPSULES CYCLIMYCIN-100 CAPSULES SCHEDULING STATUS: S4 PROPRIETARY NAME (and dosage form): CYCLIMYCIN-50 CAPSULES CYCLIMYCIN-100 CAPSULES COMPOSITION: Each capsule contains: Minocycline hydrochloride equivalent to minocycline 50 or 100 mg. PHARMACOLOGICAL CLASSIFICATION: A 20.1.1 Broad and medium spectrum antibiotics. PHARMACOLOGICAL ACTION’ Cyclimycin is a bacteriostatic antibiotic and inhibits bacterial protein synthesis (30S ribosomes). It is particularly effective in vitro against the following organisms: Vibrio cholerae, Ureaplasma urealyticum, Mycoplasma pneumoniae, Chlamydia trachomatis ( see also below) Chlamydia psittaci, Borrelia recurrensis, Calymmatobacterium granulomatis, Borrelia burgdorferi, penicillin-sensitive Neisseria gonorrhoeae and Rickettsiae. Cyclimycin is also effective against the following organisms in vitro: Clostridium tetani, Listeria monocytogenes, Haemophilus ducreyi, Campylobacter jejuni, Leptospira, Actinomyces israelli, Bacillus anthracis*, Pasteurella multocida, Streptobacillus moniliformis, Erysipelothrix rhusiopathiae, Neisseria meningitidis contacts.Cyclimycin may also show some effect against the following organisms: Bacteroides species and Fusobacterium nucleatum. * = in vitro sensitivity tests must be performed.Resistant pathogens: Many strains of the following are resistant: Staphylococci Enterococci Proteus vulgaris Fungi and yeasts (except Actinomyces) Pseudomonas aeruginosa (all strains) E. coli Shigella Strep. pneumoniaeMinocycline is well absorbed and its half-life is long (16-18 hours). Plasma concentrations at the usual dosage range are between 1-3 µg/mL. Minocycline is widely distributed into pleural and peritoneal fluid, saliva semen and prostatic fluid. It passes the placental barrier readily and is also present in the milk of lactating patients. It is c Belgenin tamamını okuyun