CURAM DUO 400/57 pos
Ülke: Avustralya
Dil: İngilizce
Kaynak: Department of Health (Therapeutic Goods Administration)
Ürün özellikleri
(SPC)
26-05-2024
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Aktif bileşen:
Amoxycillin trihydrate; Potassium clavulanate
Mevcut itibaren:
Sandoz Pty Ltd
Sınıf:
Medicine Registered
Ürün özellikleri
_Product Information _
_ _
_Page 1 _
_Curam Duo 400/57 amoxycillin/clavulanic acid 400+57mg/5mL Powder for Suspension _
_07/2012 _
_Sandoz Pty Ltd _
_ _
_ _
_ _
PRODUCT INFORMATION
CURAM DUO 400/57 POWDER FOR SUSPENSION
NAME OF THE MEDICINE
_Chemical name:_
_ _
(2_S_,5_R_,6_R_)-6-[[(2_R_)-2-Amino-2-(4-hydroxyphenyl)acetyl]amino]-
3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid trihydrate.
_Generic name: Amoxycillin trihydrate _
_Chemical structure: _
_ _
_ _
_ _
_CAS [61336-70-7] _
_Empirical formula: _C
16
H
19
N
3
O
5
S.3H
2
O
MW: 419.5
_ _
_ _
_ _
_Chemical name: _potassium (2_R_,3_Z_,5_R_)-3-(2-hydroxyethylidene)-7-oxo-4-oxa-1-
azabicyclo[3.2.0]heptane-2-carboxylate.
_Generic name: potassium clavulanate _
_Chemical structure: _
_ _
_ _
_ _
_ _
_CAS [61177-45-5] _
_Empirical formula: _C
8
H
8
KNO
5
_ _
_ _
MW:_ _237.3
DESCRIPTION
Curam Duo 400/57 is a combination product containing the semisynthetic antibiotic,
amoxycillin (as the trihydrate) and the beta-lactamase inhibitor, clavulanic acid (as the
potassium salt).
Amoxycillin is susceptible to hydrolysis by beta-lactamases.
_Product Information _
_ _
_Page 2 _
_Curam Duo 400/57 amoxycillin/clavulanic acid 400+57mg/5mL Powder for Suspension _
_07/2012 _
_Sandoz Pty Ltd _
_ _
_ _
_ _
Clavulanic acid is produced by the fermentation of _Streptomyces clavuligerus_. It is an
irreversible inhibitor of many beta-lactamase enzymes except type 1 (Richmond). It is
a beta-lactam compound with only weak antibacterial activity.
_Excipients: _Lemon Flavouring 15.12.0598, Peach-Apricot Flavouring 26F22, Citric
acid anhydrous, Sodium citrate anhydrous, Aspartame, Talc-purified, Orange
Flavouring 55301 AP0551, Guar gum and Silicon dioxide. Contains sul
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