Ülke: Yeni Zelanda
Dil: İngilizce
Kaynak: Medsafe (Medicines Safety Authority)
Benzylpenicillin sodium 1.2 g
Seqirus (NZ) Ltd
Benzylpenicillin sodium 1.2 g
1.2 g
Powder for injection
Active: Benzylpenicillin sodium 1.2 g
Vial, glass, Type III, 1 x 1.2g, 1.2 g
Prescription
Prescription
Sandoz GmbH
Package - Contents - Shelf Life: Vial, glass, Type III, 1 x 1.2g - 1.2 g - 60 months from date of manufacture stored at or below 25°C
1994-02-07
1 BENPEN TM _Benzylpenicillin (as benzylpenicillin sodium) Powder for Injection_ CONSUMER MEDICINE INFORMATION WHAT IS IN THIS LEAFLET This leaflet answers some common questions about BENPEN TM . It does not contain all the available information. It does not take the place of talking to your doctor and pharmacist. All medicines have risks and benefits. Your doctor has weighed the risks of you taking BENPEN TM against the benefits this medicine is expected to have for you. IF YOU HAVE ANY CONCERNS ABOUT TAKING THIS MEDICINE, ASK YOUR DOCTOR OR PHARMACIST. Keep this leaflet. You may need to read it again. WHAT BENPEN TM IS USED FOR BENPEN TM is an antibiotic used to treat some infections in different parts of the body caused by bacteria. BENPEN TM may also be used to prevent infections before, during and after surgery. BENPEN TM will not work against infections caused by viruses, such as colds or the flu. BENPEN TM is an antibiotic that belongs to a group of medicines called penicillins. These antibiotics work by killing the bacteria that are causing your infection. Your doctor may have prescribed BENPEN TM for another reason. Ask your doctor why BENPEN TM has been prescribed for you. This medicine is available only with a doctors prescription. There is no evidence that BENPEN TM is addictive. BEFORE YOU ARE GIVEN BENPEN TM _WHEN YOU MUST NOT BE GIVEN IT_ DO NOT USE BENPEN TM IF: ∃ YOU HAVE AN ALLERGY TO BENPEN TM OR OTHER PENICILLINS. Some of the symptoms of an allergic reaction may include skin rash, itching and difficult breathing. ∃ YOU HAVE HAD AN ALLERGIC REACTION TO CEPHALOSPORINS. You may have an increased chance of being allergic to BENPEN TM if you Belgenin tamamını okuyun
Page 1 of 3 NAME OF MEDICINE BENPEN INJECTION Benzylpenicillin Sodium 600mg, 1.2g and 3g/vial PRESENTATION White powder in vial nominally containing 600mg, 1.2g or 3g of Benzylpenicillin Sodium. These presentations contain no other excipients. USES ACTIONS Benzylpenicillin is bactericidal and is active against most Gram-positive organisms e.g. pneumococci, streptococci, non-beta-lactamase- producing staphylococci, clostridia and some Gram-negative organisms, eg. gonococci and meningococci. It is also active against spirochetes such as _Treponema pallidum_ PHARMACOKINETICS Benzylpenicillin appears rapidly in the blood after intramuscular injection, maximum concentrations being reached in 20 to 30 minutes. The concentration with a particular dose varies in different patients and in the same patient on different occasions. Serum concentrations of penicillin have been reported to range from 1.2 to 12 µg per mL, 3 to 6 hours after the intramuscular injection of 60 to 600 mg. The minimum effective serum-penicillin concentration is about 0.02 µg per mL for sensitive organisms, but higher levels (0.03 to 0.06 µg per mL) are required in the treatment of sub-acute bacterial endocarditis or infections due to relatively less sensitive organisms. The half- life of benzylpenicillin when given intramuscularly is 30 minutes. Benzylpenicillin diffuses across the placenta into the foetal circulation and small amounts may appear in the milk of nursing mothers. However, very little passes into the cerebrospinal fluids except when the meninges are inflamed. Small amounts are excreted in the bile. It is rapidly excreted by the renal tubules, causing a steep decline in serum-penicillin concentrations; up to 60% of a single intramuscular dose may appear in the urine within 1 hour of administration and 95% within 4 hours. The renal tubular excretion of penicillin can be partly blocked by probenecid, but t Belgenin tamamını okuyun