Adrenaline (base) 100micrograms/1ml (1 in 10,000) dilute solution for injection pre-filled syringes

Ülke: Birleşik Krallık

Dil: İngilizce

Kaynak: MHRA (Medicines & Healthcare Products Regulatory Agency)

Aktif bileşen:

Adrenaline acid tartrate

Mevcut itibaren:

base) 100micrograms/1ml (1 in 10,000) dilute solution for injection pre-filled syringes (Martindale Pharmaceuticals Ltd

ATC kodu:

C01CA24

INN (International Adı):

Adrenaline acid tartrate

Doz:

100microgram/1ml

Farmasötik formu:

Solution for injection

Uygulama yolu:

Intraosseous; Intravenous

Sınıf:

No Controlled Drug Status

Reçete türü:

Valid as a prescribable product

Ürün özeti:

BNF: 02070300; GTIN: 5026468000388

Bilgilendirme broşürü

0000
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100MM MEASUREMENT VERIFICATION BAR
D04017
D04003
WHAT IS IN THIS LEAFLET:
1.
What Adrenaline injection is, and what it is used for
2.
What you need to know before Adrenaline injection
is given
3.
How Adrenaline injection is given
4.
Possible side effects
5.
How to store Adrenaline injection
6.
Contents of the pack and other information
1. WHAT ADRENALINE INJECTION IS, AND WHAT IT
IS USED FOR
Adrenaline injection belongs to a group of medicines
called adrenergic and dopaminergic agents.
THIS MEDICINE IS USED FOR:
• Treatment of cardiac arrest (unexpected loss of heart
function, breathing and consciousness),
• Treatment of acute anaphylaxis in adults (serious
shock or collapse produced by a severe allergic
reaction).
2. WHAT YOU NEED TO KNOW BEFORE YOU ARE
GIVEN ADRENALINE INJECTION
YOU MUST NOT BE GIVEN ADRENALINE INJECTION:
If you are allergic (hypersensitive) to any ingredients of
this medicine (listed in section 6) where an alternative
presentation of Adrenaline or alternative vasopressor is
available.
WARNINGS AND PRECAUTIONS
Adrenaline injection is indicated for emergency
treatment. Continuous medical supervision is
necessary after administration.
PRECAUTIONS FOR USE
The risk of side effects is increased if you:
• have medical history of hyperthyroidism (disease of
the thyroid gland),
• have severe renal insufficiency,
• suffer from hypercalcaemia (increase of calcium
concentration in the blood),
• suffer from hypokalaemia (decrease of potassium
concentration in the blood),
• have diabetes mellitus,
• have cardiac disease or arterial hypertension,
• have brain damage or hardening of the arteries in the
brain,
• have glaucoma (increased pressure in the eye),
• have prostate disorders,
• are elderly,
• are pregnant.
OTHER MEDICINES AND ADRENALINE INJECTION
Tell your doctor if you are taking, have recently taken or
might take any other medicines.
Medicines that may interact with Adrenaline injection
include:
• Volatile halogen anaesthetics (gas used during
anaesthesia),
•

Ürün özellikleri

OBJECT 1
ADRENALINE (EPINEPHRINE) INJECTION 1:10,000
(GLASS PREFILLED SYRINGE)
Summary of Product Characteristics Updated 20-Apr-2018 | Martindale
Pharma
1. Name of the medicinal product
Adrenaline (Epinephrine) Injection 1:10,000
2. Qualitative and quantitative composition
Each ml of solution for injection contains 0.1 mg of adrenaline (as
adrenaline acid tartrate)
Each 10 ml pre-filled syringe contains 1 mg adrenaline (as adrenaline
acid tartrate)
Excipient with known effect: sodium
Each ml of solution for injection contains 2.695 mg equivalent to
0.117 mmol of sodium.
Each 10 ml pre-filled syringe contains 26.95 mg equivalent to 1.17
mmol of sodium.
For a full list of excipients, see section 6.1.
3. Pharmaceutical form
A sterile aqueous clear and colourless solution for slow intravenous
injection in pre-filled syringe.
4. Clinical particulars
4.1 Therapeutic indications
Adrenaline (Epinephrine) Injection 1 in 10,000 may be used in the
• Cardiopulmonary Resuscitation in adults and children over 5kg
• Acute anaphylaxis in adults
4.2 Posology and method of administration
THIS MEDICINAL PRODUCT IS NOT INTENDED TO DELIVER VOLUMES OF LESS THAN
2 ML.
INTRAVENOUS ADRENALINE SHOULD ONLY BE ADMINISTERED BY THOSE
EXPERIENCED IN THE USE AND TITRATION OF
VASOPRESSORS IN THEIR NORMAL CLINICAL PRACTICE.
CARDIOPULMONARY RESUSCITATION:
10 ml of the 1:10,000 solution (1 mg) by the intravenous or
intraosseous route, repeated every 3-5
minutes until return of spontaneous circulation.
Endotracheal use should only be considered as a last resort if no
other route of administration is
accessible, at a dose of 20 to 25 ml of the 1:10,000 solution (2 to
2.5 mg).
In cardiac arrest following cardiac surgery, Adrenaline should be
administered intravenously in doses of
0.5 ml or 1ml of 1:10,000 solution (50 or 100 micrograms) very
cautiously and titrated to effect.
ACUTE ANAPHYLAXIS:
Titrate using intravenous boluses of 0.5 ml 1:10,000 solution (0.05
mg) according to response.
Adrenaline 1mg/10ml (1:10,000) solution for injection in pr