AA-Amilzide Tablet 50mg5mg

Ülke: Malezya

Dil: İngilizce

Kaynak: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)

Aktif bileşen:

AMILORIDE HYDROCHLORIDE; HYDROCHLOROTHIAZIDE

Mevcut itibaren:

PHARMAFORTE (MALAYSIA) SDN. BHD.

INN (International Adı):

AMILORIDE HYDROCHLORIDE; HYDROCHLOROTHIAZIDE

Paketteki üniteler:

1000Tablet Tablets; 500 Tablet Tablets

Tarafından üretildi:

APOTEX INC

Bilgilendirme broşürü

AA-AMILZIDE TABLET
Hydrochlorothiazide/ Amiloride Hydrochloride (50mg/5mg)
1
_CONSUMER MEDICATION INFORMATION LEAFLET (RIMUP)_
WHAT IS IN THIS LEAFLET
1.
What AA-Amilzide is used for
2.
How AA-Amilzide works
3.
Before you use AA-Amilzide
4.
How to use AA-Amilzide
5.
While you are using it
6.
Side effects
7.
Storage and Disposal of AA-
Amilzide
8.
Product Description
9.
Manufacturer and Product
Registration Holder
10.
Date of revision
WHAT
AA-AMILZIDE
IS USED FOR
The combination of hydrochlorothiazide
and
amiloride
is
used
to
treat
fluid
retention
(edema)
and
high
blood
pressure (hypertension).
HOW AA-AMILZIDE WORKS
Hydrochlorothiazide is a thiazide diuretic
(water
pill)
that
helps
prevent
your
kidney from reabsorbing too much salt,
which can cause fluid retention.
Amiloride is a potassium sparing-diuretic
that also prevents your kidney from
reabsorbing too much salt and keeps
your potassium levels from getting too
low.
BEFORE YOU USE AA-AMILZIDE
-
_When you must not use it_
You should not use this medication if
you are allergic to hydrochlorothiazide or
amiloride
You should not use this medication if
you have hyperkalemia (High serum
potassium level), have impaired kidney
function, or have diabetes.
_ _
_Pregnancy and lactation _
Do not take AA-Amilzide if you are
pregnant, trying to get pregnant or think
you may be pregnant.
Do not take AA-Amilzide if you are
breast-feeding. Ask your doctor or
pharmacist for advice before taking any
medicine.
-
_Before you start to use it_
Before you start to take this
medication, let your doctor know if
you have any other medical condition.
-
_Taking other medicines_
Some medications, when taken
together with AA-Amilzide will cause
complications if no proper precaution
is taken. These medications include
hypertensive drugs (potentiation),
Litium (litium toxicity), as well as
supplements such as potassium
supplements.
Tell your doctor if you are taking any
other medicines, including any that
you buy without a prescription from a
pharmacy, supermarket or health food
shop.
HOW TO

Ürün özellikleri

AA-AMILZIDE
HYDROCHLOROTHIAZIDE AND AMILORIDE HYDROCHLO-
RIDE TABLETS USP 50MG/5MG
DIURETIC - ANTIHYPERTENSIVE
PHARMACOLOGY:
AA-AMILZIDE
(hydrochlorothiazide
and
amiloride
hydrochloride) is a diuretic/antihypertensive combining the potent
natriuretic
action of hydrochlorothiazide with the potassium conserving property
of amiloride
hydrochloride.
The
mild
diuretic
and
antihypertensive
actions
of
amiloride
hydrochloride are additive to the natriuretic, diuretic and
antihypertensive activity
of the thiazide while minimizing the loss of potassium and lessening
the likelihood
of acid base imbalance. The onset of the diuretic action of
AA-AMILZIDE is
within 1 to 2 hours and this action appears to be sustained for
approximately
24 hours.
Hydrochlorothiazide: Hydrochlorothiazide is a diuretic and
antihypertensive
agent.
It
affects
the
renal
tubular
mechanism
of
electrolyte
reabsorption.
Hydrochlorothiazide increases excretion of sodium and chloride in
approximately
equivalent amounts
and may
cause
a simultaneous, usually
minimal,
loss
of
bicarbonate. Natriuresis is usually accompanied by some loss of
potassium.
The mechanism of the antihypertensive effect of thiazides may be
related to
the excretion and redistribution of body sodium. Hydrochlorothiazide
usually
does not decrease
normal
blood
pressure.
The onset of the diuretic
action
of
hydrochlorothiazide occurs in 2 hours and the peak action in about 4
hours.
Diuretic activity lasts about 6 to 12 hours. Hydrochlorothiazide is
eliminated
rapidly by the kidney.
Amiloride Hydrochloride: Amiloride hydrochloride is an antikaliuretic
drug with mild
natriuretic diuretic and antihypertensive activity. These activities
may be additive
to the effects of thiazides or other saluretic diuretic agents. The
principal use of
amiloride hydrochloride is to conserve potassium in selected patients
receiving
kaliuretic-diuretic agents. The action
is not related
to the level
of aldosterone
excretion. Amiloride hydrochloride is not an aldosterone antagonist.
The drug
acts directly on the dis