"正和" 糖立敏錠15毫克

Ülke: Tayvan

Dil: Çince

Kaynak: 衛生福利部食品藥物管理署 (Ministry of Health and Welfare, Food And Drug Administration)

Aktif bileşen:

PIOGLITAZONE HYDROCHLORIDE

Mevcut itibaren:

正和製藥股份有限公司新營廠 台南市新營區嘉芳里新工路２３號 (72004856)

ATC kodu:

A10BG03

Farmasötik formu:

錠劑

Kompozisyon:

主成分 (Each mg tablets:) ; PIOGLITAZONE HYDROCHLORIDE (6820400910) 15MG

Paketteki üniteler:

塑膠瓶裝;;鋁箔盒裝

Sınıf:

製　劑

Reçete türü:

須由醫師處方使用

Tarafından üretildi:

正和製藥股份有限公司新營廠 台南市新營區嘉芳里新工路２３號 TW

Terapötik alanı:

pioglitazone

Terapötik endikasyonlar:

第二型糖尿病患者(非胰島素依賴型糖尿病，NIDDM)。

Ürün özeti:

有效日期: 2027/03/05; 英文品名: Diazone Tablets 15mg "C.H."

Yetkilendirme tarihi:

2007-03-05

Bilgilendirme broşürü

(40%)
HbA
1C
10.3%
240mg/dL
HbA
1C
10.4%
254mg/dL
Pioglitazone 30mg
HbA
1C
1.0%
62
mg/dL
(60%)
HbA
1C
9.4%
216mg/dL
HbA
1C
10.6
%
287mg/dL
Pioglitazone 30mg
HbA
1C
1.3%
46mg/dL
HbA
1C
2.
16
metformin
sulfonylurea
insulin
2
(HbA
1C
8%)
Pioglitazone
560
sulfonylurea
2
Pioglitazone 15mg
30mg
sulfonylurea
Pioglitazone
sulfonylurea
Pioglitazone 15mg
Pioglitazone 30mg
HbA
1C
0.9% 1.3%
Pioglitazone 15mg
Pioglitazone 30mg
39mg/dL
58mg/dL
sulfonylurea (
<50% 50% >50%
)
Pioglitazone
sulfonylurea
328
metformin
2
Pioglitazone 30mg
metformin
Pioglitazone
metformin
HbA
1C
0.8%
38mg/dL (
<2000mg
2000
mg)
Pioglitazone
metformin
566
60.5
(
)
Pioglitazone 15mg
30mg
Pioglitazone
HbA
1C
(Pioglitazone 15mg
0.7% Pioglitazone 30mg
1.0%)
(Pioglitazone 15mg
35mg/dL
Pioglitazone 30mg
49mg/dL)
(
<60.5
60.5
)
Pioglitazone
25
2~1000
048602
Pioglitazone 30mg
HbA
1C
(
%)
(
)
+ +
(
)
+ +
(
)
(mg/dL)
(
)
+ +
(
)
+ +
(
)
N=93
10.3
0.8
N=91
270
8
N=100
10.5
-0.6
-1.4
N=99
273
-50
-58
+
Adjusted for baseline , pooled center and pooled center by treatment
interaction.
p<0.050 VS.
(
NIDDM)
pioglitazone
2
pioglitazone
pioglitazone
sulfonylurea
metformin
insulin
2
1.
pioglitazone
15mg
30mg
pioglitazone
45 mg
2.
(1)Sulfonylurea
sulfonylurea
pioglitazone
15 mg
30 mg
pioglitazone
sulfonylurea
sulfonylurea
(2)Metformin
metformin
pioglitazone
15mg
30mg
pioglitazone
metformin
pioglitazone
metformin
(3)Insulin
insulin
pioglitazone
15mg
30mg
pioglitazone
insulin
pioglitazone
insulin
100mg/dL
insulin
10%~25%
3.
sulfonylurea
Metformin
insulin
pioglitazone
45 mg
4.
(
-2.
)
transaminase
(ALT>2.5
)
pioglitazone
(
-
-
)
pioglitazone
(
-
)
pioglitazone
18
pioglitazone
thiazolidinedione
Pioglitazone
thiazolidinedione
Pioglitazone
peroxisome proliferatoractiv-
ated receptor-gamma (PPAR
)
PPAR
PPAR
Pioglitazone
2
Pioglitazone
Pioglitazone
Pioglitazone (Pioglitazone+
)
24
7
Pioglitazone
Pioglitazone
Pioglitazone
2
(M-
)
(M-
)
Pioglitazone
2
Pioglitazone
Pioglitazone
30%~50%
(AUC)
20%~25%
15mg
30mg
Pioglitazone
Pioglitazone
(Cmax)
(Cmin)
60mg
30
Pioglitazone
2
3~4
Pioglit