Nchi: Malesia
Lugha: Kiingereza
Chanzo: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)
Cefuroxime Axetil
NOVARTIS CORPORATION (MALAYSIA) SDN. BHD.
Cefuroxime Axetil
10 Tablets
Glaxo Operations UK Limited
_CONSUMER MEDICATION INFORMATION LEAFLET (RIMUP) _ 1 ZINNAT TABLET Cefuroxime axetil (250mg, 500mg) WHAT IS IN THIS LEAFLET 1. What ZINNAT is used for 2. How ZINNAT works 3. Before you use ZINNAT 4. How to use ZINNAT 5. While you are using it 6. Side Effects 7. Storage and Disposal of ZINNAT 8. Product Description 9. Manufacturer and Product Registration Holder 10. Date of Revision WHAT ZINNAT IS USED FOR ZINNAT is used in adults and children to treat infections of the: • Ears, nose and throat • Lungs or chest • Urinary tract • Skin and soft tissues ZINNAT is also used to treat: • Sexually transmitted infections Your doctor should test the type of bacteria causing your infection and monitor whether the bacteria are sensitive to ZINNAT during your treatment. HOW ZINNAT WORKS ZINNAT belongs to a group of antibiotics called cephalosporins. It works by killing bacteria that cause infections. BEFORE YOU USE ZINNAT - _When you must not use it _ _ _ Do not take ZINNAT: - if you are allergic ( _hypersensitive_ ) to cefuroxime or cephalosporin antibiotics or any of the other ingredients of ZINNAT. ZINNAT is not recommended for children aged under 3 months, as it has not been adequately studied in this age group. - _Before you start to use it _ _ _ Special care is indicated if you have experienced an allergic reaction to penicillin or other beta-lactam antibiotic (penicillins, monobactams and carbapenems). There is only limited information about the safety of ZINNAT in pregnant women. If you are pregnant your doctor will discuss with you if the benefits of taking ZINNAT outweigh the possible risks to your baby. The ingredients in ZINNAT can pass into breast milk. If you are breast-feeding, you must check with your doctor before you take ZINNAT. - _Taking other medicines _ _ _ Tell your doctor or pharmacist if you’re taking any other medicines, if you’ve taken any recently, or if you start taking new ones. This includes medicines bought without a prescription. Medicines used to reduce the amount of acid in you Soma hati kamili
ZINNAT CEFUROXIME AXETIL QUALITATIVE AND QUANTITATIVE COMPOSITION _ZINNAT_ tablets containing either 250 or 500 mg of cefuroxime (as cefuroxime axetil). PHARMACEUTICAL FORM Zinnat Tablets 250mg: White, film-coated, capsule-shaped tablets engraved “GXES7” on one side and plain on the other. Zinnat Tablets 500mg: White to off white, capsule shaped, bi-convex tablets engraved “GXEG2” on one side and plain on the other. CLINICAL INFORMATION INDICATIONS _ZINNAT _ is an oral prodrug of the bactericidal cephalosporin antibiotic cefuroxime, which is resistant to most β (beta)-lactamases and is active against a wide range of Gram-positive and Gram-negative organisms. It is indicated for the treatment of infections caused by susceptible bacteria. Susceptibility to _ZINNAT_ will vary with geography and time and local susceptibility data should be consulted where available (See _Pharmacological properties, Pharmacodynamics_ ). _ _ INDICATIONS INCLUDE: – upper respiratory tract infections for example, ear, nose and throat infections, such as otitis media, sinusitis, tonsillitis and pharyngitis – lower respiratory tract infections for example, pneumonia, acute bronchitis, and acute exacerbations of chronic bronchitis – genito-urinary tract infections for example, pyelonephritis, cystitis and urethritis – skin and soft tissue infections for example, furunculosis, pyoderma and impetigo – gonorrhoea, acute uncomplicated gonococcal urethritis, and cervicitis Cefuroxime is also available as the sodium salt ( _ZINACEF_ ) for parenteral administration. This permits the use of sequential therapy with the same antibiotic, when a change from parenteral to oral therapy is clinically indicated. Where appropriate _ZINNAT_ is effective when used following initial parenteral _ZINACEF_ (cefuroxime sodium) in the treatment of pneumonia and acute exacerbations of chronic bronchitis. DOSAGE AND ADMINISTRATION The usual course of therapy is seven days (range 5 to 10 days). _ZINNAT _ should be taken after food for optimum absorp Soma hati kamili