XYLOCAINE- lidocaine hydrochloride injection, solution XYLOCAINE- lidocaine hydrochloride and epinephrine bitartrate injection,

Nchi: Marekani

Lugha: Kiingereza

Chanzo: NLM (National Library of Medicine)

Viambatanisho vya kazi:

LIDOCAINE HYDROCHLORIDE (UNII: V13007Z41A) (LIDOCAINE - UNII:98PI200987)

Inapatikana kutoka:

Physicians Total Care, Inc.

INN (Jina la Kimataifa):

LIDOCAINE HYDROCHLORIDE

Tungo:

LIDOCAINE HYDROCHLORIDE 10 mg in 1 mL

Njia ya uendeshaji:

INFILTRATION

Dawa ya aina:

PRESCRIPTION DRUG

Matibabu dalili:

Xylocaine (lidocaine HCl) Injections are indicated for production of local or regional anesthesia by infiltration techniques such as percutaneous injection and intravenous regional anesthesia by peripheral nerve block techniques such as brachial plexus and intercostal and by central neural techniques such as lumbar and caudal epidural blocks, when the accepted procedures for these techniques as described in standard textbooks are observed. Lidocaine HCl is contraindicated in patients with a known history of hypersensitivity to local anesthetics of the amide type.

Bidhaa muhtasari:

All solutions should be stored at 20° to 25°C (68° to 77°F) [see USP Controlled Room Temperature].  Protect from light. All trademarks are the property of APP Pharmaceuticals, LLC. 451175B Revised:  March 2010 Additional barcode applied by: Physicians Total Care, Inc. Tulsa, OK      74146

Idhini hali ya:

New Drug Application

Tabia za bidhaa

XYLOCAINE - LIDOCAINE HYDROCHLORIDE INJECTION, SOLUTION
XYLOCAINE - LIDOCAINE HYDROCHLORIDE AND EPINEPHRINE BITARTRATE
INJECTION, SOLUTION
PHYSICIANS TOTAL CARE, INC.
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XYLOCAINE
For Infiltration and Nerve Block
Rx only
DESCRIPTION
Xylocaine (lidocaine HCl) Injections are sterile, nonpyrogenic,
aqueous solutions that contain a local
anesthetic agent with or without epinephrine and are administered
parenterally by injection. See
INDICATIONS for specific uses.
Xylocaine solutions contain lidocaine HCl, which is chemically
designated as acetamide, 2-
(diethylamino)-N-(2,6-dimethylphenyl)-, monohydrochloride and has the
molecular wt. 270.8.
Lidocaine HCl (C
H N O • HCl) has the following structural formula:
Epinephrine is (-) -3, 4-Dihydroxy-α-[(methylamino) methyl] benzyl
alcohol and has the molecular wt.
183.21. Epinephrine (C H NO ) has the following structural formula:
Dosage forms listed as Xylocaine-MPF indicate single dose solutions
that are Methyl Paraben Free
(MPF).
Xylocaine MPF is a sterile, nonpyrogenic, isotonic solution containing
sodium chloride. Xylocaine in
multiple dose vials: Each mL also contains 1 mg methylparaben as
antiseptic preservative. The pH of
these solutions is adjusted to approximately 6.5 (5.0 to 7.0) with
sodium hydroxide and/or hydrochloric
acid.
Xylocaine MPF with Epinephrine is a sterile, nonpyrogenic, isotonic
solution containing sodium
chloride. Each mL contains lidocaine hydrochloride and epinephrine,
with 0.5 mg sodium metabisulfite
as an antioxidant and 0.2 mg citric acid as a stabilizer. Xylocaine
with Epinephrine in multiple dose
vials: Each mL also contains 1 mg methylparaben as antiseptic
preservative. The pH of these solutions
is adjusted to approximately 4.5 (3.3 to 5.5) with sodium hydroxide
and/or hydrochloric acid. Filled
under nitrogen.
14
22
2
9
13
3
CLINICAL PHARMACOLOGY
MECHANISM OF ACTION
Lidocaine HCl stabilizes the neuronal membrane by inhibiting the ionic
fluxes required for the initiation
and conduction of impulses thereby effecting local anesthet