Uphalexin Capsule 250mg

Nchi: Malesia

Lugha: Kiingereza

Chanzo: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)

Viambatanisho vya kazi:

CEPHALEXIN MONOHYDRATE

Inapatikana kutoka:

Duopharma Marketing Sdn. Bhd.

INN (Jina la Kimataifa):

CEPHALEXIN MONOHYDRATE

Vitengo katika mfuko:

10x10 Capsules

Viwandani na:

KOTRA PHARMA (M) SDN. BHD.

Taarifa za kipeperushi

_CONSUMER MEDICATION INFORMATION LEAFLET (RIMUP) _
UPHALEXIN CAPSULE
Cephalexin Monohydrate equivalent to Cephalexin (250mg & 500mg)
1
WHAT IS IN THIS LEAFLET
1.
What Uphalexin Capsule is used
for
2.
How Uphalexin Capsule works
3.
Before
you
use
Uphalexin
Capsule
4.
How to use Uphalexin Capsule
5.
While you are using it
6.
Side effects
7.
Storage
and
Disposal
of
Uphalexin Capsule
8.
Product Description
9.
Manufacturer
and
Product
Registration Holder
10.
Date of revision
WHAT UPHALEXIN CAPSULE IS USED FOR
Uphalexin
Capsule
is
an
antibiotic
which is indicated in the treatment of
the
following
infections
due
to
susceptible microorganisms:
•
Respiratory tract infections
•
Otitis media (ear infection)
•
Bone infections
•
Genitourinary
(urinary)
tract
infections,
including
acute
prostatitis
•
Dental infections
HOW UPHALEXIN CAPSULE WORKS
Cephalexin is an antibiotic that
belongs to the group of medicines
called
cephalosporin.
These
medicines work by killing or stopping
the growth of the bacteria, which
cause infections.
BEFORE YOU USE UPHALEXIN CAPSULE
_-When you must not use it _
Do not take Uphalexin Capsule if:
•
You are allergic or hypersensitive
to cephalosporin.
•
It is not prescribed by a qualified
doctor or pharmacist for you.
•
You are pregnant, trying to get
pregnant
or
think
you
may
be
pregnant.
•
You are breast-feeding. Ask your
doctor or pharmacist for advice
before taking any medicine.
_-Before you start use it _
Tell your doctor if:
•
You
are
allergic
to
any
medicines, food and dyes.
•
You
are
taking
any
other
medicines
(including
those
not
prescribed by your doctor).
•
You are allergic or hypersensitive
to Penicillin.
•
You are having renal impairment.
•
You are pregnant and nursing
mother.
_-Taking other medicines _
You should tell your doctor if you are
taking
the following medicine
as
it
may
interact
with
your
Uphalexin
Capsule:
•
Oestrogen
containing
oral
contraceptives (birth control pill).
•
Probenecid
(medicines
used
to
treat
chronic
gout
and
gouty
arthritis).
•
N

Tabia za bidhaa

COMPOSITION
PHARMACOKINETICS
INDICATIONS
PHARMACODYNAMICS
Each capsule contains:
Uphalexin Capsule 500mg:
Cephalexin Monohydrate equivalent to Cephalexin 500mg
Uphalexin Capsule 250mg:
Cephalexin Monohydrate equivalent to Cephalexin 250mg
Uphalexin Capsule 500mg: Pink/purple hard gelatin capsule, size 0
Uphalexin Capsule 250mg: Pink/Ruby red hard gelatin capsule, size 2
Cephalexin is bactericidal; its action depending on its ability to
bind penicillin-binding
proteins located in bacterial cytoplasmic membranes. Cephalexin
inhibits synthesis of
bacterial septum and cell wall pr
obably by acylation of transpeptidases enzymes. These
enzymes are responsible for the cross linking of peptidoglycan chains,
which is
necessary for the bacterial cell wall strength and rigidity. Cell
division and growth are
also inhibited. Rapidly dividing bacteria are those most susceptible
to the action of
cephalexin.
Cephalexin is almost completely absorbed from the gastrointestinal
tract. If cephalexin
is taken with food, absorption may be delayed, but the total amount
absorbed is not
appreciably altered. It is widely distributed in the body but does not
enter the
cerebrospinal fluids in significant quantities. It is not metabolised.
About 80% or more
of a dose is excreted unchanged in the urine.
Contraindicated in patient hypersensitive to cephalosporin.
Cephalexin should be used with caution for patient with penicillin
sensitivity. False
positive urinary glucose and false positive Combs’ test have been
found during the
treatment of Cephalexin. Patients with renal impairment should be
given with caution.
Pseudomembranous colitis has been reported with nearly all
antibacterial agents,
including cephalexin, and may range from mild to life threatening.
Therefore, it is
important to consider this diagnosis in patients with diarrhea
subsequent to the
administration of cephalexin. Prolonged use of cephalexin may result
in the overgrowth
of
nonsusceptible
organisms.
Careful
observation
of
the
patients
is
essential.
If
superinfection occurs