Nchi: Marekani
Lugha: Kiingereza
Chanzo: NLM (National Library of Medicine)
Tiletamine (UNII: 2YFC543249) (Tiletamine - UNII:2YFC543249), Zolazepam (UNII: G1R474U58U) (Zolazepam - UNII:G1R474U58U)
Dechra Veterinary Products LLC
Tiletamine
Tiletamine 50 mg in 1 mL
INTRAMUSCULAR
PRESCRIPTION
Dogs: Tzed is indicated in dogs for restraint and minor procedures of short duration (30 min. avg.) requiring mild to moderate analgesia. Minor surgery is considered to be laceration repair, draining of abscesses, castrations and other procedures requiring mild to moderate analgesia. (See Dogs under Dosage and Administration.) Tzed administered intravenously is indicated in dogs for induction of anesthesia followed by maintenance with an inhalant anesthetic. Cats: Tzed is indicated in cats for restraint or for anesthesia combined with muscle relaxation. The use of Tzed is contraindicated in dogs and cats with pancreatic disease. Tzed should not be used in dogs and cats with severe cardiac or pulmonary dysfunction. Because the teratogenic potential of Tzed is unknown, it should not be used in pregnant bitches or queens at any stage of pregnancy. Also, a study has shown that tiletamine and zolazepam crosses the placental barrier and produces respiratory depression in the newborn; therefore, its use for Cesar
Tzed (tiletamine and zolazepam for injection) is available in individual vials of 5 mL solution when reconstituted. The addition of 5 mL diluent produces a solution containing the equivalent of 50 mg tiletamine base, 50 mg zolazepam base and 57.7 mg mannitol per milliliter. NDC 17033-010-05: 100 mg/mL total (equivalent to 50 mg/mL tiletamine and 50 mg/mL zolazepam) when reconstituted Approved by FDA under ANADA # 200-557
Abbreviated New Animal Drug Application
TZED (TILETAMINE HYDROCHLORIDE AND ZOLAZEPAM HYDROCHLORIDE)- TILETAMINE AND ZOLAZEPAM INJECTION DECHRA VETERINARY PRODUCTS LLC ---------- TZED™ CIII (TILETAMINE AND ZOLAZEPAM FOR INJECTION) 100 mg/mL total (equivalent to 50 mg/mL tiletamine and 50 mg/mL zolazepam) For Intramuscular and Intravenous injection in Dogs For Intramuscular injection only in Cats CAUTION Federal (USA) law restricts this drug to use by or on the order of a licensed veterinarian. DESCRIPTION Tzed (tiletamine and zolazepam for injection) is a nonnarcotic, nonbarbiturate, injectable anesthetic agent for dogs and cats. Chemically, Tzed is a combination of equal parts by weight of base of tiletamine hydrochloride (2-[ethylamino]-2-[2-thienyl]-cyclohexanone hydrochloride), an arylaminocycloalkanone dissociative anesthetic, and zolazepam hydrochloride (4-[o-fluorophenyl]-6, 8-dihydro-1,3,8-trimethylpyrazolo [3, 4-e] [1,4] diazepin-7 [1H]-1- hydrochloride), a non-phenothiazine diazepinone having minor tranquilizing properties. The product is supplied sterile in vials. The addition of 5 mL diluent produces a solution containing the equivalent of 50 mg tiletamine base, 50 mg zolazepam base and 57.7 mg mannitol per milliliter. This solution has a pH of 2 to 3.5 and is recommended for deep intramuscular injection. INDICATIONS DOGS: Tzed is indicated in dogs for restraint and minor procedures of short duration (30 min. avg.) requiring mild to moderate analgesia. Minor surgery is considered to be laceration repair, draining of abscesses, castrations and other procedures requiring mild to moderate analgesia. (See Dogs under Dosage and Administration.) Tzed administered intravenously is indicated in dogs for induction of anesthesia followed by maintenance with an inhalant anesthetic. CATS: Tzed is indicated in cats for restraint or for anesthesia combined with muscle relaxation. DOSAGE AND ADMINISTRATION THE DOSE IS DETERMINED BY THE TOTAL COMBINED CONCENTRATION OF 100 MG/ML (SEE HOW SUPPLIED) DOGS: _INTRAMUSCULAR (IM) FOR RESTRAINT AND MINOR PROCEDUR Soma hati kamili