Marekani - Kiingereza - NLM (National Library of Medicine)

teva pharmaceuticals usa, inc. - tretinoin (unii: 5688utc01r) (tretinoin - unii:5688utc01r) - tretinoin 10 mg - tretinoin capsules are indicated for the induction of remission in adults and pediatric patients 1 year of age and older with acute promyelocytic leukemia (apl) characterized by the presence of the t(15;17) translocation or pml/rarα gene expression, and who are refractory to or who have relapsed from anthracycline chemotherapy or for whom anthracycline-based chemotherapy is contraindicated. tretinoin capsules are contraindicated in patients with a known hypersensitivity to tretinoin, any of its components, or other retinoids. reactions have included rash, pruritus, face edema, and dyspnea. [see adverse reactions (6.1)] . risk summary based on findings in animals and its mechanism of action [see clinical pharmacology (12.1)] , tretinoin can cause embryo-fetal loss and malformations when administered to a pregnant woman. tretinoin is a retinoid and there is an increased risk of major congenital malformations, spontaneous abortions and premature births following exposure to retinoids during pregnancy in human

Marekani - Kiingereza - NLM (National Library of Medicine)

par pharmaceutical, inc. - tretinoin (unii: 5688utc01r) (tretinoin - unii:5688utc01r) - tretinoin 10 mg - tretinoin capsules are indicated for the induction of remission in adults and pediatric patients 1 year of age and older with acute promyelocytic leukemia (apl) characterized by the presence of the t(15;17) translocation or pml/rarα gene expression, and who are refractory to or who have relapsed from anthracycline chemotherapy or for whom anthracycline-based chemotherapy is contraindicated. tretinoin capsules are contraindicated in patients with a known hypersensitivity to tretinoin capsules, any of its components, or other retinoids. reactions have included rash, pruritus, face edema, and dyspnea. [see adverse reactions (6.1)]. risk summary based on findings in animals and its mechanism of action [see clinical pharmacology (12.1)], tretinoin capsules can cause embryo-fetal loss and malformations when administered to a pregnant woman. tretinoin capsules are a retinoid and there is an increased risk of major congenital malformations, spontaneous abortions and premature births following exposure to retinoids d

Marekani - Kiingereza - NLM (National Library of Medicine)

avkare - tretinoin (unii: 5688utc01r) (tretinoin - unii:5688utc01r) - tretinoin 10 mg - tretinoin capsules are indicated for the induction of remission in patients with acute promyelocytic leukemia (apl), french-american-british (fab) classification m3 (including the m3 variant), characterized by the presence of the t(15;17) translocation and/or the presence of the pml/rarα gene who are refractory to, or who have relapsed from, anthracycline chemotherapy, or for whom anthracycline-based chemotherapy is contraindicated. tretinoin capsules are for the induction of remission only. the optimal consolidation or maintenance regimens have not been defined, but all patients should receive an accepted form of remission consolidation and/or maintenance therapy for apl after completion of induction therapy with tretinoin capsules. tretinoin capsules are contraindicated in patients with a known hypersensitivity to tretinoin capsules, any of its components, or other retinoids. tretinoin capsules should not be given to patients who are sensitive to parabens, which are used as preservatives in the gelatin caps

Marekani - Kiingereza - NLM (National Library of Medicine)

obagi cosmeceuticals llc - tretinoin (unii: 5688utc01r) (tretinoin - unii:5688utc01r) - tretinoin 0.05 g in 100 g - tretinoin gel is indicated for topical treatment of acne vulgaris. none. pregnancy category c there are no well-controlled trials in pregnant women treated with tretinoin gel. tretinoin gel should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. tretinoin gel at doses of 0.1, 0.3 and 1 g/kg/day was tested for maternal and developmental toxicity in pregnant sprague-dawley rats by dermal application. the dose of 1 g/kg/day was approximately 4 times the clinical dose assuming 100% absorption and based on body surface area comparison. possible tretinoin-associated teratogenic effects (craniofacial abnormalities (hydrocephaly), asymmetrical thyroids, variations in ossification, and increased supernumerary ribs) were noted in the fetuses of tretinoin gel treated animals. these findings were not observed in control animals. other maternal and reproductive parameters in the tretinoin gel treated animals were not different from control. for purposes of comparison of the

Marekani - Kiingereza - NLM (National Library of Medicine)

dispensing solutions, inc. - tretinoin (unii: 5688utc01r) (tretinoin - unii:5688utc01r) - tretinoin 1 mg in 1 g - tretinoin gel and cream are indicated for topical application in the treatment of acne vulgaris. the safety and efficacy of the long-term use of this product in the treatment of other disorders have not been established. use of the product should be discontinued if hypersensitivity to any of the ingredients is noted. safety and effectiveness in pediatric patients below the age of 12 have not been established. safety and effectiveness in a geriatric population have not been established. clinical studies of tretinoin did not include sufficient numbers of subjects aged 65 and over to determine whether they respond differently from younger patients.

Marekani - Kiingereza - NLM (National Library of Medicine)

physicians total care, inc. - tretinoin (unii: 5688utc01r) (tretinoin - unii:5688utc01r) - tretinoin 0.025 mg in 1 g - tretinoin is indicated for topical application in the treatment of acne vulgaris. the safety and efficacy of the long-term use of this product in the treatment of other disorders have not been established. use of the product should be discontinued if hypersensitivity to any of the ingredients is noted.

Marekani - Kiingereza - NLM (National Library of Medicine)

spear dermatology products inc - tretinoin (unii: 5688utc01r) (tretinoin - unii:5688utc01r) - tretinoin 1 mg in 1 g - tretinoin gel microsphere , 0.1% and 0.04%, is a retinoid indicated for topical application in the treatment of acne vulgaris. none. there are no adequate and well-controlled studies in pregnant women. tretinoin gel microsphere should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. thirty human cases of temporally associated congenital malformations have been reported during two decades of clinical use of tretinoin gel microsphere , 0.1% and 0.04%. although no definite pattern of teratogenicity and no causal association has been established from these cases, five of the reports describe the rare birth defect category holoprosencephaly (defects associated with incomplete midline development of the forebrain). the significance of these spontaneous reports in terms of risk to the fetus is not known. for purposes of comparison of the animal exposure to systemic human exposure, the maximum recommended human dose (mrhd) applied topically is defined as 1 gram of tre

Marekani - Kiingereza - NLM (National Library of Medicine)

obagi cosmeceuticals llc - tretinoin (unii: 5688utc01r) (tretinoin - unii:5688utc01r) - tretinoin 1 mg in 1 g - tretinoin is indicated for topical application in the treatment of acne vulgaris. the safety and efficacy of the long-term use of this product in the treatment of other disorders have not been established. use of the product should be discontinued if hypersensitivity to any of the ingredients is noted.

Marekani - Kiingereza - NLM (National Library of Medicine)

zo skin health, inc. - tretinoin (unii: 5688utc01r) (tretinoin - unii:5688utc01r) - tretinoin 0.5 mg in 1 g - (to understand fully the indication for this product, please read the entire indications and usage section of the labeling.) tretinoin cream, usp (emollient) 0.05% is indicated as an adjunctive agent (see second bullet point below) for use in the mitigation (palliation) of fine wrinkles, mottled hyperpigmentation, and tactile roughness of facial skin in patients who do not achieve such palliation using comprehensive skin care and sun avoidance programs (see bullet 3 for populations in which effectiveness has not been established). tretinoin cream, usp (emollient) does not eliminate wrinkles, repair sun-damaged skin, reverse photoaging, or restore a more youthful or younger dermal histologic pattern. many patients achieve desired palliative effects on fine wrinkling, mottled hyperpigmentation, and tactile roughness of facial skin with the use of comprehensive skin care and sun avoidance programs including sunscreens, protective clothing, and emollient creams not containing tretinoin. - tretinoin cream, usp

Marekani - Kiingereza - NLM (National Library of Medicine)

rouses point - tretinoin (unii: 5688utc01r) (tretinoin - unii:5688utc01r) - tretinoin 1 mg in 1 g - tretinoin gel and cream are indicated for topical application in the treatment of acne vulgaris. the safety and efficacy of the long-term use of this product in the treatment of other disorders have not been established. use of the product should be discontinued if hypersensitivity to any of the ingredients is noted.