Nulox 7.5 Orodispersible Tablet 7.5mg
Nchi: Singapoo
Lugha: Kiingereza
Chanzo: HSA (Health Sciences Authority)
Taarifa za kipeperushi
(PIL)
08-03-2013
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Viambatanisho vya kazi:
Meloxicam
Inapatikana kutoka:
EURO ASIA MEDICO PTE. LTD.
ATC kanuni:
M01AC06
Kipimo:
7.50mg
Dawa fomu:
TABLET, ORALLY DISINTEGRATING
Njia ya uendeshaji:
ORAL
Dawa ya aina:
Prescription Only
Viwandani na:
Alpex Pharma SA
Idhini ya tarehe:
2012-10-15
Taarifa za kipeperushi
NULOX
®
7.5
NULOX
®
15
MELOXICAM ORODISPERSIBLE TABLET
PRESENTATION
Nulox
®
7.5 contains meloxicam 7.5 mg per tablet and are light yellow, flat, and embossed with
AX6 on one side.
Nulox
®
15 contains meloxicam 15 mg per tablet and are light yellow, flat, scored and embossed
with AX5 on one side.
The other ingredients are mannitol (E421), aspartame (E951), sorbitol (E420), citric acid anhydrous
(E330), yoghurt flavour, forest fruit flavour, povidone (E1201), talc (E553b), sodium lauryl sulfate and
magnesium stearate (E572).
PHARMACODYNAMIC PROPERTIES
ATC code: M01AC06
Nulox
®
is a non-steroidal anti-inflammatory drug (NSAID) of the enolic acid class, which has shown
anti-inflammatory, analgesic and antipyretic properties in animals. Meloxicam showed potent anti-
inflammatory activity in all standard models of inflammation. A common mechanism for the above
effects may exist in the ability of meloxicam to inhibit the biosynthesis of prostaglandins, known
mediators of inflammation.
Comparison of the ulcerogenic dose and the anti-inflammatory effective dose in the rat adjuvant
arthritis model confirmed a superior therapeutic margin in animals over standard NSAIDs. In vivo,
meloxicam inhibited prostaglandin biosynthesis more potently at the site of inflammation than in the
gastric mucosa or the kidney.
These differences are thought to be related to a selective inhibition of COX-2 relative to COX-1 and it
is believed that COX-2 inhibition provides the therapeutic effects of NSAIDs whereas inhibit
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