HYDROXYZINE HYDROCHLORIDE syrup

Nchi: Marekani

Lugha: Kiingereza

Chanzo: NLM (National Library of Medicine)

Viambatanisho vya kazi:

HYDROXYZINE DIHYDROCHLORIDE (UNII: 76755771U3) (Hydroxyzine - UNII:30S50YM8OG)

Inapatikana kutoka:

Proficient Rx LP

INN (Jina la Kimataifa):

Hydroxyzine Hydrochloride

Tungo:

Hydroxyzine Hydrochloride 10 mg in 5 mL

Njia ya uendeshaji:

ORAL

Dawa ya aina:

PRESCRIPTION DRUG

Matibabu dalili:

For symptomatic relief of anxiety and tension associated with psychoneurosis and as an adjunct in organic disease states in which anxiety is manifested. Useful in the management of pruritus due to allergic conditions such as chronic urticaria and atopic and contact dermatoses, and in histamine-mediated pruritus. As a sedative when used as premedication and following general anesthesia, hydroxyzine may potentiate meperidine and barbiturates , so their use in pre-anesthetic adjunctive therapy should be modified on an individual basis. Atropine and other belladonna alkaloids are not affected by the drug. Hydroxyzine is not known to interfere with the action of digitalis in any way and it may be used concurrently with this agent. The effectiveness of hydroxyzine as an antianxiety agent for long term use, that is more than 4 months, has not been assessed by systematic clinical studies. The physician should reassess periodically the usefulness of the drug for the individual patient. Oral hydroxyzine hydrochloride i

Bidhaa muhtasari:

Hydroxyzine Hydrochloride Oral Solution, USP (Syrup) 10 mg per 5 mL (teaspoonful) is a colorless, peppermint-flavored syrup, supplied in 4 fl oz (118 mL) bottles. NDC 63187-494-04 Store at 20° to 25°C (68° to 77°F) [see USP Controlled Room Temperature]. PROTECT FROM FREEZING PROTECT FROM LIGHT Dispense in a tight, light-resistant container as defined in the USP, with child-resistant closure.

Idhini hali ya:

Abbreviated New Drug Application

Tabia za bidhaa

HYDROXYZINE HYDROCHLORIDE- HYDROXYZINE HYDROCHLORIDE SYRUP
PROFICIENT RX LP
----------
HYDROXYZINE HYDROCHLORIDE ORAL SOLUTION, USP (SYRUP)
10 MG/5 ML
RX ONLY
DESCRIPTION
Hydroxyzine hydrochloride is designated chemically as
(±)-2-[2-[4-(_p_-Chloro-α-
phenylbenzyl)-1-piperazinyl]ethoxy]ethanol dihydrochloride. Its
structural formula is as
follows:
INACTIVE INGREDIENTS for Hydroxyzine Hydrochloride Oral Solution, USP
(Syrup) are:
alcohol 0.5%; liquid sugar; methylparaben; peppermint oil; propylene
glycol;
propylparaben; purified water and spearmint oil. IT MAY ALSO CONTAIN
citric acid
anhydrous or sodium citrate dihydrate for pH adjustment. The pH range
is between 2.0
and 4.3.
CLINICAL PHARMACOLOGY
Hydroxyzine hydrochloride is unrelated chemically to the
phenothiazines, reserpine,
meprobamate, or the benzodiazepines.
Hydroxyzine is not a cortical depressant, but its action may be due to
a suppression of
activity in certain key regions of the subcortical area of the central
nervous system.
Primary skeletal muscle relaxation has been demonstrated
experimentally.
Bronchodilator activity, and antihistaminic and analgesic effects have
been
demonstrated experimentally and confirmed clinically. An antiemetic
effect, both by the
apomorphine test and the veriloid test, has been demonstrated.
Pharmacological and
clinical studies indicate that hydroxyzine in therapeutic dosage does
not increase gastric
secretion or acidity and in most cases has mild antisecretory
activity. Hydroxyzine is
rapidly absorbed from the gastrointestinal tract and its clinical
effects are usually noted
within 15 to 30 minutes after oral administration.
INDICATIONS AND USAGE
For symptomatic relief of anxiety and tension associated with
psychoneurosis and as an
adjunct in organic disease states in which anxiety is manifested.
Useful in the management of pruritus due to allergic conditions such
as chronic urticaria
and atopic and contact dermatoses, and in histamine-mediated pruritus.
As a sedative when used as premedication and following general
ane