Nchi: Australia
Lugha: Kiingereza
Chanzo: Department of Health (Therapeutic Goods Administration)
cefazolin sodium
Pfizer Australia Pty Ltd
cefazolin sodium
Registered
________________________________________________________________________________ HOSPIRA™ Cefazolin Sodium Powder for Injection CMI Page 1 HOSPIRA™ CEFAZOLIN SODIUM POWDER FOR INJECTION Cefazolin Sodium _(ke-fä-zö-lin)_ CONSUMER MEDICINE INFORMATION _Date of Dispensing_ _Consumer Name _ _Pharmacist Name _ _Consumer Address _ _Pharmacist Address _ WHAT IS IN THIS LEAFLET This leaflet answers some common questions about Hospira™ Cefazolin Sodium Powder for Injection. It does not contain all the available information. It does not take the place of talking to your doctor or pharmacist. All medicines have risks and benefits. Your doctor has weighed the risks of you being given cefazolin against the benefits they expect it will have for you. IF YOU HAVE ANY CONCERNS ABOUT BEING GIVEN THIS MEDICINE, ASK YOUR DOCTOR OR PHARMACIST. KEEP THIS LEAFLET._ _ You may need to read it again. WHAT HOSPIRA™ CEFAZOLIN SODIUM POWDER FOR INJECTION IS USED FOR Cefazolin is an antibiotic used to treat infections in different parts of the body caused by bacteria. Cefazolin will not work against infections caused by viruses such as colds or the flu. This medicine belongs to a group of antibiotics called cephalosporins _(ke-fä-lö-spör-_ _ins)._ It works by killing the bacteria causing your infection or by stopping its growth. ASK YOUR DOCTOR IF YOU HAVE ANY QUESTIONS ABOUT WHY THIS MEDICINE HAS BEEN PRESCRIBED FOR YOU . Your doctor may have prescribed it for another reason. This medicine is not addictive. _ _ It is available only with a doctor’s prescription. BEFORE YOU ARE GIVEN HOSPIRA™ CEFAZOLIN SODIUM POWDER FOR INJECTION _WHEN YOU MUST NOT BE _ _GIVEN IT _ YOU MUST NOT BE GIVEN HOSPIRA™ CEFAZOLIN SODIUM POWDER FOR INJECTION IF YOU HAVE AN ALLERGY TO: • any medicine containing cefazolin • any other cephalosporin antibiotics. Some of the symptoms of an allergic reaction may include shortness of breath, wheezing or difficulty breathing; swelling of the face, lips, tongue or other parts of the body; rash, itching or Soma hati kamili
Product Information - Australia_ _ Version 1.0 Page 1 HOSPIRA™ CEFAZOLIN SODIUM POWDER FOR INJECTION NAME OF THE MEDICINE Cefazolin sodium Chemical Name: Sodium (6 _R, _ 7 _R_ )-3-[[(5-methyl-1, 3, 4-thiadiazol-2-yl)sulphanyl]methyl]-8-oxo-7- [(1 _H_ -tetrazol-1-ylacetyl) amino]-5-thia-1-azabicyclo[4.2.0] oct-2-ene-2-carboxylate Molecular formula: C 14 H 13 N 8 NaO 4 S 3 Molecular weight: 476.5 CAS: 27164-46-1 DESCRIPTION Cefazolin sodium is a white to off white crystalline powder with a solubility in water of greater than or equal to 100 mg/mL. Hospira™ Cefazolin Sodium Powder for Injection contains cefazolin sodium as a single ingredient. Hospira™ Cefazolin Sodium Powder for Injection is a powder for parenteral administration following reconstitution. Each vial contains 1.05 _ _ g of cefazolin sodium which is approximately equivalent to 1 _ _ g of cefazolin. Each gram of cefazolin sodium contains 48.3 _ _ mg of sodium. PHARMACOLOGY MICROBIOLOGY _In vitro_ tests demonstrate that the bactericidal action of cephalosporins results from inhibition of cell wall synthesis. Cefazolin sodium is active against the following organisms _in vitro_ : _Staphylococcus aureus_ (penicillin-sensitive and penicillin-resistant). Group A beta-haemolytic streptococci and other strains of streptococci (many strains of enterococci are resistant). _Streptococcus pneumoniae _ _ _ _Klebsiella species_ _Escherichia coli _ _ _ _ _ _Enterobacter aerogenes_ Product Information - Australia_ _ Version 1.0 Page 2 _Proteus mirabilis _ _ _ _ _ _Haemophilus influenzae _ Most strains of _Enterobacter cloacae_ and indole-positive _Proteus (Pr. vulgaris, Pr. morganii, Pr. _ _rettgeri)_ are resistant. Methicillin-resistant Staphylococci, _Serratia, Pseudomonas, Acinetobacter _ _calcoaceticus _ (formerly _Mima_ and _Herellea_ species) are almost uniformly resistant to cefazolin. _Disc Susceptibility tests _ Quantitative methods that require measurements of zone diameters give the most precise estimates of antibiotic susceptibility. One such proced Soma hati kamili