FUROSEMIDE 1%- furosemide syrup

Nchi: Marekani

Lugha: Kiingereza

Chanzo: NLM (National Library of Medicine)

Viambatanisho vya kazi:

FUROSEMIDE (UNII: 7LXU5N7ZO5) (FUROSEMIDE - UNII:7LXU5N7ZO5)

Inapatikana kutoka:

FIRST PRIORITY INCORPORATED

INN (Jina la Kimataifa):

FUROSEMIDE

Tungo:

FUROSEMIDE 10 mg in 1 mL

Njia ya uendeshaji:

ORAL

Dawa ya aina:

PRESCRIPTION

Matibabu dalili:

A diuretic-saluretic for prompt relief of edema. Furosemide Syrup 1% is an effective diuretic possessing a wide therapeutic range. Pharmacologically it promotes the rapid removal of abnormally retained extracellular fluids. The rationale for the efficacious use of diuretic therapy is determined by the clinical pathology producing the edema. Furosemide Syrup 1% is indicated for the treatment of edema (pulmonary congestion, ascites) associated with cardiac insufficiency and acute noninflammatory tissue edema. The continued USB of heart stimulants, such as digitalis or its glycosides, is indicated in cases of edema involving cardiac insufficiency. Furosemide Syrup 1% is a highly effective diureticsaluretic which if given in excessive amounts may result in dehydration and electrolyte imbalance. Therefore, the dosage and schedule may have to be adjusted to the patients' needs. The animal should be observed for early signs of electrolyte imbalance, and corrective measures administered. Early signs of electrolyte im

Bidhaa muhtasari:

Furosemide Syrup 1% (10 mg/mL), available in 60 mL bottles with calibrated safety dropper.

Idhini hali ya:

Abbreviated New Animal Drug Application

Tabia za bidhaa

FUROSEMIDE 1%- FUROSEMIDE SYRUP
FIRST PRIORITY INCORPORATED
----------
FUROSEMIDE SYRUP 1 % (10 MG/ML)
WITH CALIBRATED SAFETY DROPPER
FOR USE IN DOGS ONLY
CAUTION: Federal law restricts this drug to use by or on the order of
a licensed
veterinarian.
NOT FOR USE IN HUMANS • KEEP OUT OF REACH OF CHILDREN
Approved by FDA under ANADA # 200-373
A DIURETIC-SALURETIC FOR PROMPT RELIEF OF EDEMA.
DESCRIPTION:
Furosemide Syrup 1% is a chemically distinct diuretic and saluretic
pharmacodynamically
characterized by the following:
1) A high degree of efficacy, low-inherent toxicity and a high
therapeutic index.
2) A rapid onset of action of comparatively short duration.
3) A pharmacologic action in the functional area of the nephron, i.e.,
proximal and distal
tubules and the ascending limb of the loop Henle.
4) A dose-response relationship and a ratio of minimum to maximum
effective dose
range greater than ten fold.
5) It is administered orally. It is readily absorbed from the
intestinal tract and well
tolerated.
The CAS Registry Number is: 54-31-9. This product contains alcohol
11.5% USP as a
preservative, and FD&C Yellow #6 and D&C Yellow #10 as color
additives.
Furosemide Syrup 1%, a diuretic, is an anthranilic acid derivative
with the following
structural formula:
Generic name: Furosemide (except in United Kingdomfrusemide). Chemical
name: 4-
chloro-N-furfuryl-5- sulfamoylanthranilic acid.
ACTIONS
The therapeutic efficacy of Furosemide Syrup 1 % is from the activity
of the intact and
unaltered molecule throughout the nephron, inhibiting the reabsorption
of sodium not
1,2
2,4
1,2
only in the proximal and distal tubule, but also in the ascending limb
of the loop of Henle.
The prompt onset of action is a result of the drug's rapid absorption
and a poor lipid
solubility. The low lipid solubility and a rapid renal excretion
minimizes the possibility of
lipid accumulation in tissues and organs or of crystalluria.
Furosemide Syrup 1 % has no
inhibitory effect on carbonic anhydrase or aldosterone activity in the
distal tubule.