Nchi: Nyuzilandi
Lugha: Kiingereza
Chanzo: Medsafe (Medicines Safety Authority)
Atropine sulfate monohydrate 1.2 mg/mL
Juno Pharmaceuticals NZ Limited
Atropine sulfate monohydrate 1.2 mg/mL
1.2 mg/mL
Solution for injection
Active: Atropine sulfate monohydrate 1.2 mg/mL Excipient: Hydrochloric acid Sodium chloride Water for injection
Ampoule, glass, 50x1mL, 50 mL
Prescription
Prescription
Boehringer Ingelheim Pharma GmbH & Co KG
Package - Contents - Shelf Life: Ampoule, glass, 50x1mL - 50 mL - 18 months from date of manufacture stored at or below 25°C - Polyamp, Duofit 50x1mL - 50 mL - 18 months from date of manufacture stored at or below 25°C
1984-11-29
NEW ZEALAND DATA SHEET Page 1 of 11 1. NAME OF MEDICINE Atropine Sulfate Injection, atropine sulfate 600 mcg/mL solution for injection. 2. QUALITATIVE AND QUANTITATIVE COMPOSITION Atropine Sulfate 0.06% w/v For the full list of excipients, see section 6.1. 3. PHARMACEUTICAL FORM Solution for injection. 4. CLINICAL PARTICULARS 4.1 THERAPEUTIC INDICATIONS Surgery Atropine may be given as a pre-anaesthetic medication to inhibit excessive salivary and bronchial secretions and to diminish the risk of vagal inhibition of the heart. The use of Atropine as an antisialagogue is rarely necessary since the introduction of halothane and similar anaesthetics in place of ether anaesthesia. Atropine may be administered concurrently with anticholinesterase agents (e.g. neostigmine, physostigmine) to block the adverse muscarinic effects when they are used after surgery to terminate curarisation. Cardiopulmonary Resuscitation It may be used in the management of patients with acute myocardial infarction and sinus bradycardia who have associated hypotension and increased ventricular irritability. Anticholinesterase Poisoning It is also used concomitantly with a cholinesterase reactivator (e.g. pralidoxime) to reverse muscarinic effects associated with toxic exposure to anticholinesterase compounds (e.g. organophosphate pesticides). Atropine may be used in conjunction with morphine or other agents for the relief of biliary or renal colic. 4.2 DOSAGE AND ADMINISTRATION Atropine may be administered by subcutaneous (SC), intramuscular (IM) or direct intravenous (IV) injection. The product contains no antimicrobial agent. It should be used only once and any residue discarded. Atropine sulfate should not be added to any IV infusion solution. SURGERY Adults: 300 to 600 mcg IM or SC, approximately 1 hour before anaesthesia, usually in conjunction with a narcotic. Alternatively, 300 to600 mcg may be given IV immediately prior to induction Page 2 of 11 of anaesthesia. To reverse the effects of non depolarising muscle relaxants, 600 mcg to 1.2 Soma hati kamili