Nchi: Marekani
Lugha: Kiingereza
Chanzo: NLM (National Library of Medicine)
ISOLEUCINE (UNII: 04Y7590D77) (ISOLEUCINE - UNII:04Y7590D77), LEUCINE (UNII: GMW67QNF9C) (LEUCINE - UNII:GMW67QNF9C), LYSINE ACETATE (UNII: TTL6G7LIWZ) (LYSINE - UNII:K3Z4F929H6), METHIONINE (UNII: AE28F7PNPL) (METHIONINE - UNII:AE28F7PNPL), PHENYLALANINE (UNII: 47E5O17Y3R) (PHENYLALANINE - UNII:47E5O17Y3R), THREONINE (UNII: 2ZD004190S) (THREONINE - UNII:2ZD004190S), TRYPTOPHAN (UNII: 8DUH1N11BX) (TRYPTOPHAN - UNII:8DUH1N11BX), VALINE (UNII: HG18B9YRS7) (VALINE - UNII:HG18B9YRS7), ALANINE (UNII: OF5
Hospira, Inc.
INTRAVENOUS
PRESCRIPTION DRUG
Aminosyn-PF 10%, Sulfite-Free, (an amino acid injection — pediatric formula) is indicated for the nutritional support of infants (including those of low birth weight) and young children requiring TPN via either central or peripheral infusion routes. Parenteral nutrition with Aminosyn-PF 10% is indicated to prevent nitrogen and weight loss or treat negative nitrogen balance in infants and young children where (1) the alimentary tract by the oral gastrostomy, or jejunostomy route, cannot or should not be used or adequate protein intake is not feasible by these routes; (2) gastrointestinal absorption of protein is impaired; or (3) protein requirements are substantially increased as with extensive burns. Dosage, route of administration, and concomitant infusion of non-protein calories are dependent on various factors, such as nutritional and metabolic status of the patient, anticipated duration of parenteral nutrition support, and vein tolerance. See DOSAGE AND ADMINISTRATION for additional information. Centr
Aminosyn -PF 10%, Sulfite-Free, (an amino acid injection — pediatric formula) is supplied as a Pharmacy Bulk Package in 1000 mL flexible plastic containers NDC 0409-4179-05. Store at 20 to 25°C (68 to 77°F). [See USP Controlled Room Temperature.] Protect from freezing. It is recommended that the product be stored at room temperature (25°C). Avoid exposure to light. Revised: June, 2008 Printed in USA EN-1817 Hospira, Inc., Lake Forest, IL 60045 USA
New Drug Application
AMINOSYN-PF- ISOLEUCINE, LEUCINE, LYSINE ACETATE, METHIONINE, PHENYLALANINE, THREONINE, TRYPTOPHAN, VALINE, ALANINE, ARGININE, ASPARTIC ACID, GLUTAMIC ACID, GLYCINE, HISTIDINE, PROLINE, SERINE, TAURINE, AND TYROSINE INJECTION, SOLUTION HOSPIRA, INC. ---------- AMINOSYN -PF 10% SULFITE-FREE _AN AMINO ACID INJECTION - PEDIATRIC FORMULA_ PHARMACY BULK PACKAGE − NOT FOR DIRECT INFUSION. Flexible Plastic Container R only DESCRIPTION Aminosyn -PF 10%, Sulfite-Free, (an amino acid injection — pediatric formula) is a sterile, nonpyrogenic solution for intravenous infusion. Aminosyn-PF 10% is oxygen sensitive. The Pharmacy Bulk Package is a sterile dosage form which contains multiple single doses for use only in a pharmacy bulk admixture program. The formulation is described below: AMINOSYN-PF 10% AN AMINO ACID INJECTION — PEDIATRIC FORMULA ESSENTIAL AMINO ACIDS (MG/100 ML) Isoleucine 760 Leucine 1200 Lysine (acetate)* 677 Methionine 180 Phenylalanine 427 Threonine 512 Tryptophan 180 Valine 673 * Amount cited is for lysine alone and does not include the acetate salt. NONESSENTIAL AMINO ACIDS (MG/100 ML) Alanine 698 Arginine 1227 Aspartic Acid 527 Glutamic Acid 820 Glycine 385 Histidine 312 Proline 812 Serine 495 Taurine 70 Tyrosine 44 ® x ® ELECTROLYTES (MEQ/L) Sodium (Na ) None Potassium (K ) None Chloride (Cl ) None Acetate (C H O ) 46 PRODUCT CHARACTERISTICS Protein Equivalent (Approx. grams/L) 100 Total Nitrogen (grams/L) 15.2 Osmolarity (mOsmol/L) 788 pH (range) 5.5 (5.0 to 6.5) Specific Gravity 1.03 From lysine acetate. The formulas for the individual amino acids present in Aminosyn-PF 10% are as follows: ESSENTIAL AMINO ACIDS Isoleucine CH CH CH(CH )CH(NH )COOH Leucine (CH ) CHCH CH(NH )COOH Lysine Acetate H N(CH ) CH(NH )COOH • CH COOH Methionine CH S(CH ) CH(NH )COOH Phenylalanine Threonine CH CH(OH)CH(NH )COOH Tryptophan Valine (CH ) CHCH(NH )COOH NONESSENTIAL AMINO ACIDS Alanine CH CH(NH )COOH Arginine H NC(NH)NH(CH ) CH(NH )COOH L-Aspartic Acid HOOCCH CH(NH )COOH L-Glutamic Acid HOOC(CH ) CH(NH )COOH Soma hati kamili