PHARMANIAGA CIPROFLOXACIN TABLET 500MG

Country: Малезија

Језик: Енглески

Извор: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)

Активни састојак:

CIPROFLOXACIN HYDROCHLORIDE

Доступно од:

PHARMANIAGA MANUFACTURING BERHAD

INN (Међународно име):

CIPROFLOXACIN HYDROCHLORIDE

Јединице у пакету:

100 Tablets; 30 Tablets; 20 Tablets; 10 Tablets

Произведен од:

PHARMANIAGA MANUFACTURING BERHAD

Информативни летак

PHARMANIAGA CIPROFLOXACIN TABLET
Ciprofloxacin Hydrochloride (500mg)
1
_CONSUMER MEDICATION INFORMATION LEAFLET (RIMUP)_
WHAT IS IN THIS LEAFLET
1.
What
Pharmaniaga
Ciprofloxacin
Tablet is used for
2.
How
Pharmaniaga
Ciprofloxacin
Tablet works
3.
Before
you
use
Pharmaniaga
Ciprofloxacin Tablet
4.
How
to
use
Pharmaniaga
Ciprofloxacin Tablet
5.
While you are using it
6.
Side effects
7.
Storage and Disposal of Pharmaniaga
Ciprofloxacin Tablet
8.
Product Description
9.
Manufacturer
and
Product
Registration Holder
10.
Date of revision
WHAT
PHARMANIAGA
CIPROFLOXACIN
TABLET IS USED FOR
Pharmaniaga Ciprofloxacin Tablet is used
to
treat
certain
infections
caused
by
bacteria: infections of the: -
•
respiratory tract
•
ear, sinus cavity, eyes
•
kidney/urinary tract
•
genital
organs,
including
inflammation
of
uterus,
sexually
transmitted infection, inflammation of
the prostate
•
gastrointestinal tract, inflammation of
the inner wall of the abdomen
•
skin and soft tissues
•
bones and joints
•
bacteria in the blood
•
infection in individuals with reduced
immunity
Treatment
should be
initiated
only by
physicians who are experienced in the
treatment of severe infections.
HOW
PHARMANIAGA
CIPROFLOXACIN
TABLET WORKS
Pharmaniaga Ciprofloxacin Tablet is an
antibiotic
belonging
to
the
fluoroquinolone
family.
The
active
substance is ciprofloxacin.
Ciprofloxacin works by killing bacteria
that cause infections. It only works with
specific strains of bacteria.
BEFORE
YOU
USE
PHARMANIAGA
CIPROFLOXACIN TABLET
_-When you must not use it _
Do not take Pharmaniaga Ciprofloxacin
Tablet if you are:
•
Allergic
(hypersensitive)
to
the
Ciprofloxacin hydrochloride, to other
quinolone drugs or to any of the other
ingredients
of
Pharmaniaga
Ciprofloxacin Tablet.
_Pregnancy and lactation _
It
is
preferable
to
avoid
the
use
of
Pharmaniaga Ciprofloxacin Tablet during
pregnancy. Tell your doctor if you are
planning to get pregnant.
Do not take Pharmaniaga Ciprofloxacin
Tablet
during
breast
feeding
because
ciprofloxacin is excreted in b

Карактеристике производа

IDEALPRINS INDUSTRIES SDN BHD
CIPROFLOXACIN TABLET 500MG LEAFLET (FRONT)
REV 12
DATE: 24-11-2021
SIZE: 210MM (W) X 200MM (H)
COLOR: BLACK
DESCRIPTION
White, oblong film-coated tablet with Pharmaniaga icon on one
side and scored on the other.
COMPOSITION
Each
film-coated
tablet
contains:
Ciprofloxacin
(as
hydrochloride) 500 mg.
PHARMACODYNAMICS
Ciprofloxacin
is
a
synthetic
broad
spectrum
quinolone
antibacterial agent.
Mechanism of Action: Ciprofloxacin has in-vitro against virtually
all
Gram-negative
and
Gram-positive
organisms.
The
bactericidal action of ciprofloxacin results from inhibition of
bacterial
type
II
topoisomerases
(DNA
gyrase
and
topoisomerase
IV),
which
are
required
for
bacterial
DNA
replication, transcription, repair, and recombination.
Mechanism of Resistance: In vitro resistance to ciprofloxacin is
commonly due to mutations in bacterial topoisomerases and
develops slowly through multiple-step mutations. Ciprofloxacin
resistance due to spontaneous mutations occurs at a frequency
of
between
<10-9
to
10-6.
Cross-resistance
among
fluoroquinolones may occur when resistance arises through
mutations. Single mutations may result in reduced susceptibility
rather than clinical resistance, but multiple mutations generally
result in clinical resistance to ciprofloxacin and cross-resistance
across the quinolone class. Bacterial impermeability and/or
expression
of
efflux
pumps
may
impact
ciprofloxacin
susceptibility. Plasmid-mediated resistance encoded by the qnr
gene has been reported. Resistance mechanisms that inactive
penicillins, cephalosporins, aminoglycosides, macrolides, and
tetracyclines do not interfere with the antibacterial activity of
ciprofloxacin and there is no known cross-resistance between
ciprofloxacin and other classes of antimicrobials. Organisms
resistant to these drugs may be susceptible to ciprofloxacin. The
minimal bactericidal concentration (MBC) generally does not
exceed the minimal inhibitory concentration (MIC) by more than
a factor of 2.
In vitro: _Susceptibility to Ciprofloxacin_