Држава: Аустралија
Језик: Енглески
Извор: Department of Health (Therapeutic Goods Administration)
metoclopramide hydrochloride, Quantity: 10 mg
GM Pharma International Pty Ltd
metoclopramide hydrochloride
Tablet, film coated
Excipient Ingredients: purified talc; stearic acid; macrogol 6000; pregelatinised maize starch; hypromellose; titanium dioxide; colloidal anhydrous silica; maize starch; microcrystalline cellulose
Oral
30, 50, 60, 100, 125, 150, 10, 20, 25
(S4) Prescription Only Medicine
In Adults (20 years and over): As an adjunct to X-ray examination of the stomach and duodenum. To assist in intestinal intubation. To control nausea and vomiting associated with the following conditions: intolerance to essential drugs possessing emetic properties; uraemia; radiation sickness; malignant disease; postoperative vomiting; labour; infectious diseases. There is no clear benefit in motion sickness or other labyrinth disturbances. Metoclopramide hydrochloride has been found useful in the management of gastric retention after gastric surgery. Metoclopramide hydrochloride may be useful in the treatment of diabetic gastroparesis of mild to moderate severity. Once control of diabetes has been established by diet and/or insulin, metoclopramide hydrochloride should be discontinued.,Young Adults: The use of metoclopramide hydrochloride in patients under 20 years should be restricted to the following situations: Severe intractable vomiting of known cause. Vomiting associated with radiotherapy and intolerance to cytotoxic drugs. As an aid to gastrointestinal intubation
Visual Identification: White to off-white, circular, biconvex film-coated tablets with breakline on both sides.; Container Type: Blister Pack; Container Material: PVC/PVDC/Al; Container Life Time: 36 Months; Container Temperature: Store below 25 degrees Celsius
Licence status A
2015-12-17
PCA-METOCLOPRAMIDE CMI, Version 00 Page 1 of 7 PCA-METOCLOPRAMIDE _Metoclopramide hydrochloride anhydrous _ CONSUMER MEDICINE INFORMATION WHAT IS IN THIS LEAFLET This leaflet answers some common questions about PCA-Metoclopramide. It does not contain all the available information. It does not take the place of talking to your doctor or pharmacist. All medicines have risks and benefits. Your doctor has weighed the risks of you taking PCA-Metoclopramide against the benefits they expect it will have for you. IF YOU HAVE ANY CONCERNS ABOUT TAKING THIS MEDICINE, ASK YOUR DOCTOR OR PHARMACIST. KEEP THIS LEAFLET WITH THE MEDICINE. You may need to read it again. WHAT PCA-METOCLOPRAMIDE IS USED FOR In adults over 20 years this medicine is used to: treat nausea and vomiting caused by infectious diseases, kidney disease, child birth, other medications, cancer, or following surgery, chemotherapy or radiation treatment. activate stomach contractions in conditions where there is a need to encourage normal passage of food through the stomach and intestines. with X-rays to help diagnose problems of the stomach and/or intestines. help with passing tubes into the intestine. In young adults and children over 1 year of age this medicine is used to: treat severe vomiting of known cause or following chemotherapy or radiation treatment. help with passing tubes into the intestine. This medicine works by blocking the action of a chemical in the brain which causes nausea and vomiting. It also acts in the stomach and upper intestine to increase muscle contractions ASK YOUR DOCTOR IF YOU HAVE ANY QUESTIONS ABOUT WHY THIS MEDICINE HAS BEEN PRESCRIBED FOR YOU. Your doctor may have prescribed it for another reason. BEFORE YOU TAKE PCA-METOCLOPRAMIDE _ _ _WHEN YOU MUST NOT TAKE IT _ DO NOT TAKE PCA-METOCLOPRAMIDE IF YOU HAVE AN ALLERGY TO: any medicine containing Metoclopramide any of the ingredients listed at the end of this leaflet. Some of the symptoms of an allergic reaction may include: shortness of brea Прочитајте комплетан документ
PCA-Metoclopramide tablets PCA-Metoclopramide PI, Version 00 Page 1 of 8 PRODUCT INFORMATION PCA-METOCLOPRAMIDE NAME OF MEDICINE:_ _ Metoclopramide hydrochloride anhydrous. C 14 H 22 ClN 3 O 2 , HCl, H 2 O CAS number: 54143 -57-6 Molecular weight: 354.3 _ _ DESCRIPTION: Chemical name: N-(diethyl-aminoethyl)-2-methoxy-4-amino-5-chlorbenzamide monohydrochloride monohydrate. PCA-Metoclopramide tablets also contain the excipients cellulose microcrystalline, colloidal anhydrous silica, maize starch, stearic acid and pregelatinised maize starch. The coating for the tablets consists of hypromellose , macrogol 6000, titanium dioxide and purified talc. _ _ PHARMACOLOGY: Metoclopramide hydrochloride stimulates motility of the upper gastrointestinal tract without stimulating gastric, biliary, or pancreatic secretions. Its mode of action is unclear. It seems to sensitise tissues to the action of acetylcholine. The effect of metoclopramide hydrochloride on motility is not dependent on intact vagal innervation, but it can be abolished by anticholinergic drugs. Metoclopramide hydrochloride increases the tone and amplitude of gastric (especially antral) contractions, relaxes the pyloric sphincter and the duodenal bulb, and increases peristalsis of the duodenum and jejunum resulting in accelerated gastric emptying and intestinal transit. It increases the resting tone of the lower oesophageal sphincter. It has little, if any effect on the motility of the colon or gall bladder. Metoclopramide hydrochloride has dopamine antagonist activity. Like the phenothiazines and related drugs, which are also dopamine antagonists, metoclopramide hydrochloride produces sedation and may produce extra-pyramidal reactions (see PRECAUTIONS). PCA-Metoclopramide tablets PCA-Metoclopramide PI, Version 00 Page 2 of 8 Metoclopramide hydrochloride inhibits the central and peripheral effects of apomorphine, induces release of prolactin and causes a transient increase in circulating aldosterone levels. PHARMACOKINETICS _ABSORPTION: _The onset of pharmacolog Прочитајте комплетан документ