Country: Малезија
Језик: Енглески
Извор: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)
Paracetamol; Phenylephrine HCl; CHLORPHENIRAMINE MALEATE
GLAXOSMITHKLINE CONSUMER HEALTHCARE SDN. BHD.
Paracetamol; Phenylephrine HCl; CHLORPHENIRAMINE MALEATE
12 Tablets
GLAXOSMITHKLINE AUSTRALIA PTY LTD
_CONSUMER MEDICATION INFORMATION LEAFLET (RIMUP) _ PANADOL COLD+FLU-D CAPLET Paracetamol/Phenylephrine Hydrochloride/Chlorpheniramine maleate (500mg/5mg/2mg) 1 WHAT IS IN THIS LEAFLET 1. What Panadol Cold+Flu-D Caplet is used for 2. How Panadol Cold+Flu-D Caplet works 3. Before you use Panadol Cold+Flu-D Caplet 4. How to use Panadol Cold+Flu-D Caplet 5. While you are using it 6. Side effects 7. Storage and Disposal of Panadol Cold+Flu-D Caplet 8. Product Description 9. Manufacturer & Product Registration Holder 10. Date of revision WHAT PANADOL COLD+FLU-D CAPLET IS USED FOR Effective relief of runny nose, sneezing, sinus congestion and pain, itching and watery eyes. HOW PANADOL COLD+FLU-D CAPLET WORKS Paracetamol in Panadol Cold+Flu-D Caplet works to stop the pain message from getting through the brain. Paracetamol also works in the brain to reduce fever. Phenylephrine hydrochloride in Panadol Cold+Flu-D Caplet is a decongestant which unblocks your nose and sinuses helping you breathe more easily. Chlorphenamine maleate in Panadol Cold+Flu-D is an antihistamine which can help to relieve the symptoms of allergies. BEFORE YOU USE PANADOL COLD+FLU-D CAPLET _- When you must not use it _ Do not use if you are: • allergic to paracetamol, phenylephrine, chlorpheniramine, other antihistamines or any of the other ingredients in the product • taking or have taken in the past two weeks drugs called monoamine oxidase inhibitors (MAOI’s) • taking other medicines for the relief of colds and flu, congestion or blocked nose, stimulant drugs called amphetamines (sometimes used to treat attention deficit disorders), or appetite suppressants, or other medicines containing antihistamines (sometimes used to treat allergy) Do not take Panadol Cold+Flu- D Caplet if you are pregnant, trying to get pregnant or think you may be pregnant. Ask your doctor or pharmacist for advice before taking any medicine. _- Before you start to use it _ Check with your doctor before use if: • you have liver or kidney problems. • are underweigh Прочитајте комплетан документ
984630 AAAW-900 FRONT PHARMA CODE REF. NO. 1266 PRODUCT DESCRIPTION Green capsule shaped caplet with flat edges 17.7mm x 7.1mm. One face embossed with “ ” within an oval. PHARMACOLOGICAL PROPERTIES _PHARMACODYNAMICS_ This is a combination of an analgesic (paracetamol), a nasal decongestant (phenylephrine hydrochloride) and an antihistamine (chlorpheniramine maleate) for the treatment of symptoms of colds and influenza. PARACETAMOL is an analgesic and antipyretic. Its mechanism of action is believed to include inhibition of prostaglandin synthesis, primarily within the central nervous system. PHENYLEPHRINE HYDROCHLORIDE is a sympathomimetic agent with mainly direct effects on adrenergic receptors (predominantly alpha-adrenergic activity) producing nasal decongestion. CHLORPHENAMINE MALEATE is a potent antihistamine (H1-antagonist). Antihistamines diminish or abolish the actions of histamine in the body by competitive reversible blockade of histamine H1-receptor sites on tissues. Chlorpheniramine also has anticholinergic activity. _PHARMACODYNAMIC EFFECTS_ PARACETAMOL: The lack of peripheral prostaglandin inhibition confers important pharmacological properties such as the maintenance of the protective prostaglandins within the gastrointestinal tract. Paracetamol is, therefore, particularly suitable for patients with a history of disease or on concomitant medication, where peripheral prostaglandin inhibition would be undesirable (such as, for example, those with a history of gastrointestinal bleeding or the elderly) PHENYLEPHRINE HYDROCHLORIDE: Phenylephrine hydrochloride is a sympathomimetic agent with mainly direct effects on adrenergic receptors (predominantly alpha-adrenergic activity) producing nasal decongestion. CHLORPHENIRAMINE MALEATE: Antihistamines act to prevent the release of histamine, prostaglandins and leukotrienes, and have been shown to prevent the migration of inflammatory mediators. The actions of chlorpheniramine include inhibition of histamine on smooth muscle, capillary permeability and he Прочитајте комплетан документ