Country: Аустралија
Језик: Енглески
Извор: Department of Health (Therapeutic Goods Administration)
thiopental sodium, Quantity: 470 mg
Omegapharm
thiopental sodium
Injection, powder for
Excipient Ingredients:
Intravenous
100 vials, 1 vial, 50 vials, 10 vials, 25 vials
(S4) Prescription Only Medicine
? As the sole anaesthetic agent for brief surgical procedures.,? Induction of anaesthesia prior to the administration of other anaesthetic agents.,? Short-term control of convulsive states.,? Supplement to regional anaesthesia or low potency agents such as nitrous oxide.
Visual Identification: Yellowish, white powder; Container Type: Vial; Container Material: Glass Type III Clear; Container Life Time: 24 Months; Container Temperature: Store below 25 degrees Celsius; Container Closure: Neither child resistant closure nor restricted flow insert
Licence status A
2015-11-10
Omegapharm Thiopental sodium powder for injection 1/6 CMI v1.1 Oct 19 OMEGAPHARM THIOPENTAL SODIUM 470 MG POWDER FOR INJECTION thiopental sodium _(thye-oh-PEN-tal)_ _ _ CONSUMER MEDICINE INFORMATION WHAT IS IN THIS LEAFLET This leaflet answers some common questions about Omegapharm Thiopental sodium powder for injection It does not contain all the available information. It does not take the place of talking with your doctor or pharmacist. All medicines have risks and benefits. Your doctor has weighed the risks of your treatment using Omegapharm Thiopental sodium powder for injection against the benefits they expect it will have for you. IF YOU HAVE ANY CONCERNS ABOUT TAKING THIS MEDICINE, ASK YOUR DOCTOR OR PHARMACIST. KEEP THIS LEAFLET WITH THE MEDICINE. You may need to read it again. WHAT OMEGAPHARM THIOPENTAL SODIUM POWDER FOR INJECTION IS USED FOR Omegapharm Thiopental sodium powder for injection is used as a general anaesthetic, or to make you sleepy before using another anaesthetic agent, or to control seizures. This medicine belongs to a group of medicines called barbiturates. This medicine works as a short acting depressant of the nervous system, which is composed of the brain and spinal cord. It creates a sleep like state and loss of consciousness to prevent pain and discomfort during surgery. ASK YOUR DOCTOR IF YOU HAVE ANY QUESTIONS ABOUT WHY THIS MEDICINE HAS BEEN PRESCRIBED FOR YOU. Your doctor may have prescribed it for another reason. THIOPENTAL IS ADDICTIVE. This medicine is available only with a doctor's prescription. BEFORE OMEGAPHARM THIOPENTAL SODIUM POWDER FOR INJECTION IS GIVEN _WHEN OMEGAPHARM THIOPENTAL SODIUM POWDER FOR INJECTION SHOULD NOT BE USED _ _ _ YOU SHOULD NOT BE GIVEN OMEGAPHARM THIOPENTAL SODIUM POWDER FOR INJECTION IF YOU HAVE AN ALLERGY TO: • any other barbiturates; • any medicine containing thiopental sodium; or • any of the ingredients listed at the end of this leaflet. Symptoms of an allergic reaction may include: • shortness of breath; • wheezing or difficulty b Прочитајте комплетан документ
Omegapharm Thiopental Sodium 470 mg powder for Injection 1/11 PRODUCT INFORMATION OMEGAPHARM THIOPENTAL SODIUM 470 MG POWDER FOR INJECTION NAME OF THE MEDICINE Thiopental sodium Chemical name: sodium 5-ethyl-5-(1-methylbutyl)-2- thiobarbiturate. Thiopental sodium is a thiobarbiturate, the sulfur analogue of pentobarbitone sodium. It has a pKa of 7.4. The empirical formula of thiopental sodium is C11H17N2NaO2S and its molecular weight is 264.32. CAS Number: 71-73-8. ATC Code: N01AF03 DESCRIPTION Thiopental sodium is a yellowish hygroscopic powder stabilised with 30 mg anhydrous sodium carbonate per 470 mg of thiopental sodium _, equivalent to 500mg of thiopental _ _sodium and sodium carbonate._ The product is presented as a sterile powder for injection. There are no excipients in the product. PHARMACOLOGY Thiopental sodium is an ultra short-acting depressant of the central nervous system, which induces hypnosis and anaesthesia, but not analgesia. It produces hypnosis within 30 to 40 seconds of intravenous injection. Consciousness returns after 20 to 30 minutes of a single induction dose. Recovery after a small dose is rapid, with some somnolence and retrograde amnesia. The mechanism by which barbiturate anaesthetics produce general anaesthesia is not completely understood. It has been proposed that they act by enhancing responses to gamma-aminobutyric acid (GABA), diminishing glutamate responses, and directly OMEGAPHARM THIOPENTAL SODIUM 470 MG POWDER FOR INJECTION PRODUCT INFORMATION Omegapharm Thiopental sodium 470 mg powder for Injection 2/11 depressing excitability by increasing membrane conductance, thereby producing a net decrease in neuronal excitability to provide anaesthetic action. As sedative hypnotics, the barbiturates appear to act at the level of the thalamus where they inhibit ascending conduction in the reticular formation, thus interfering with the transmission of impulses to the cortex. Thiopental sodium reduces intracranial pressure. It has a dose related depression of respiratory and laryngeal Прочитајте комплетан документ