Gantin

Држава: Аустралија

Језик: Енглески

Извор: Department of Health (Therapeutic Goods Administration)

Активни састојак:

Gabapentin

Доступно од:

Pfizer Australia Pty Ltd

Класа:

Medicine Registered

Информативни летак

GANTIN
®

(GAN-TIN)
_gabapentin (gab-a-pen-tin)_
CONSUMER MEDICINE INFORMATION

WHAT IS IN THIS LEAFLET
This leaflet answers some common
questions about Gantin.
It does not contain all the available
information.
It does not take the place of talking to
your doctor or pharmacist.
All medicines have risks and
benefits. Your doctor has weighed
the risks of you taking Gantin against
the benefits it is expected to have for
you.
IF YOU HAVE ANY CONCERNS ABOUT
TAKING THIS MEDICINE, ASK YOUR
DOCTOR OR PHARMACIST.
KEEP THIS LEAFLET WITH THE MEDICINE.
You may need to read it again.
WHAT GANTIN IS USED
FOR
_WHAT GANTIN DOES_
Gantin is used to control epilepsy.
Epilepsy is a condition where you
have repeated seizures (fits). There
are many different types of seizures,
ranging from mild to severe.
Gantin is also used to treat
neuropathic pain, a type of pain
caused by damage to the nerves.
This medicine belongs to a group of
medicines called anticonvulsants.
_HOW GANTIN WORKS_
This medicine is thought to work by
controlling brain chemicals which
send signals to nerves to help control
seizures or neuropathic pain.
Gantin also has pain relieving effects.
ASK YOUR DOCTOR IF YOU HAVE ANY
QUESTIONS ABOUT WHY THIS MEDICINE
HAS BEEN PRESCRIBED FOR YOU.
Your doctor may have prescribed it
in addition to your current therapy
when your current treatment is no
longer working as well.
Your doctor may have prescribed it
for another reason.
There is no evidence that this
medicine is addictive.
This medicine is available only with
a doctor's prescription.
_USE IN CHILDREN_
There is not enough information to
recommend the use of this medicine
to control epilepsy in children under
the age of 3 years.
There is not enough information to
recommend the use of this medicine
to treat neuropathic pain in children
under the age of 18 years.
BEFORE YOU TAKE
GANTIN
_WHEN YOU MUST NOT TAKE IT_
DO NOT TAKE GANTIN IF YOU HAVE AN
ALLERGY TO:
•
any medicine containing
gabapentin, the active ingredient
in Gantin
•
any of the ingredients lis

Карактеристике производа

Version: pfpganta10413 

Supersedes:  pfpganta10711 

Page 1 of 17 
PRODUCT INFORMATION 
GANTIN
®
 (GABAPENTIN)

NAME OF THE MEDICINE 
GANTIN (gabapentin) 100 mg, 300 mg and 400 mg capsules. 
GANTIN (gabapentin) 800 mg tablets. 
GANTIN contains the active
ingredient gabapentin.  The structural formula of gabapentin
is shown 
below: 
CH
2
NH
2
C H
2
C O
2
H

Chemical name: 

1-(aminomethyl) cyclohexaneacetic acid 
Molecular formula: 

C
9
H
17
NO
2 
Molecular weight: 

171.24 
CAS Registry Number: 
60142-96-3. 
DESCRIPTION 
Gabapentin is a white to off-white crystalline solid.  It
is freely soluble in water and both basic and 
acidic aqueous solutions. 
GANTIN capsules  also  contain the inactive ingredients:
lactose, purified talc, maize  starch, gelatin 
and  titanium
dioxide.    The 300 mg capsule shell  contains  the
dye iron oxide  yellow.  The  400 mg 
capsule shell contains the dyes iron oxide yellow and iron
oxide red. 
GANTIN  tablets  also  contain  the  inactive ingredients: poloxamer,
copovidone, maize  starch, 
magnesium stearate, candelilla wax and Opadry white YS-1-18111.

PHARMACOLOGY 
PHARMACODYNAMICS 
The mechanism by which gabapentin
exerts its anticonvulsant action is unknown.  Gabapentin is 
structurally related to the neurotransmitter GABA (gamma-aminobutyric acid) but its mechanism of 
action
is different from that of several other medications that
interact with GABA synapses including 
valproate, barbiturates, benzodiazepines,
GABA transaminase inhibitors, GABA uptake inhibitors, 
GABA agonists, and GABA prodrugs.  _In vitro_  studies with
radiolabelled gabapentin have 
characterised a novel peptide binding site in rat brain
tissues including neocortex and hippocampus 
that may relate to anticonvulsant activity of gabapentin and
its structural derivatives.  Ho