Desowen

Држава: Аустралија

Језик: Енглески

Извор: Department of Health (Therapeutic Goods Administration)

Активни састојак:

Desonide

Доступно од:

Galderma Australia Pty Ltd

Класа:

Medicine Registered

Информативни летак

1 
DESOWEN 
Desonide 0.05% 

CONSUMER MEDICINE INFORMATION 

This  leaflet  answers  some  common  questions  about  DESOWEN.  Please  read  this  leaflet  carefully 
before you start using the product. It does not contain all the information available on this medicine. It 
does not take the place of talking to your doctor or pharmacist. 

All  medicines  have  risks  and  benefits.  Your  doctor  has  weighed  the  risks  of  you  using  DESOWEN 
against  the  benefits  it might  have for  you.  If  you  have  concerns  about  using  this  medicine  ask  your 
doctor or pharmacist. 

Keep this leaflet with your DESOWEN. You may wish to read it again later. 

BEFORE YOU USE DESOWEN 

WHEN YOU MUST NOT USE DESOWEN 

Do not use DESOWEN if you have ever had an allergic reaction to any of the ingredients listed in the 
section labelled ‘Ingredients’. 

Do not use DESOWEN if you have a viral skin infection (such as cold sores, shingles or chicken pox), 
a fungal skin infection (such as ringworm, thrush or tinea), or acne or rosacea unless your doctor tells 
you to. Check with your doctor to make sure you do not have any of these conditions. 

Do  not  use  DESOWEN  just  before  having  a  bath,  shower  or  going  swimming.  If  you  do  you  may 
reduce the effectiveness of this product. 

Do not apply to children under 2 years of age. 

Do not use DESOWEN after the expiry date printed on the pack. If you use it after the expiry date has 
passed it may not work as well. 

Do not use DESOWEN if the container or its seal has been damaged. 

BEFORE YOU START USING DESOWEN 

Tell your doctor if you are allergic to any other medicines, foods, dy

Карактеристике производа

PRODUCT INFORMATION 

DESOWEN 
_Desonide 0.05% _

TYPE OF APPLICATION 
DESOWEN
®
 Cream, Ointment, Lotion contains the topical corticosteroid
desonide, a nonfluorinated 
corticosteroid. 

CHEMICAL STRUCTURE_:_  
11
β, 16α, 17, 21-tetrahydroxypregna-1, 4-diene-3, 20-dione-cyclic-
16, 17-acetonide. 
MOLECULAR FORMULA:  
C
24
H
32
O
6 
, molecular weight : 416.52 

CHEMICAL ABSTRACTS NUMBER: 638-94-8 

STRUCTURAL FORMULA: 

C
O
CH2OH
HO
O
CH3
CH3
H
H
H
O
O
C
CH3
CH3
H

DESCRIPTION 

CREAM contains 0.5 mg of desonide dispersed in 1g of vehicle
buffered to the pH range of normal 
skin. It contains propylene glycol, polysorbate 60, emulsifying wax,
isopropyl palmitate, stearic acid, 
synthetic beeswax, propyl gallate, citric acid, sodium hydroxide and
purified water. It is preserved with 
sorbic acid and potassium sorbate. 

OINTMENT contains 0.5 mg of desonide in a 1g of base consisting of
liquid paraffin and polyethylene. 

LOTION contains 0.5 mg of desonide in 1 g of lotion vehicle
consisting of sodium lauryl sulfate, light 
liquid paraffin, cetyl alcohol, stearyl alcohol, propylene glycol,
methyl hydroxybenzoate, propyl 
hydroxybenzoate, sorbitan monostearate, self emulsifying
glyceryl monostearate, edetate sodium and 
purified water. The lotion may contain citric acid and/or sodium
hydroxide for pH adjustment. 

PHARMACOLOGY 

_Pharmacodynamic Properties _

Topical corticosteroids share anti-inflammatory, anti-pruritic and
vasoconstrictive actions. The 
mechanism of anti-inflammatory activity is unclear. There is evidence
to suggest a correlation 
between vasoconstriction and therapeutic efficacy in man. The
McKenzie-Stoughton vasoconstrictor 
assay yields a ranking on a seven-point scale in which the first rank
is the most potent. This assay 
method has been used to compare and predict potencies and/or clinical
efficacies of the topical 
corticosteroids. Desonide 0.05% is a group VI corticosteroid when
assessed in this way. The